Browsing by Author "Martínez Winkler, Jorge"

Now showing items 1-6 of 6

    • Adipogenic effect of calcium sensing receptor activation 
      Villarroel, Pia; Reyes Jedlicki, Marcela; Fuentes, Cecilia; Segovia, María Pia; Tobar, Nicolás; Villalobos, Elisa; Martínez Winkler, Jorge; Hugo, Eric; Ben-Jonathan, Nira; Cifuentes, Mariana (Springer, 2013)
      We established that human adipose cells and the human adipose cell line LS14 express the calciumsensing receptor (CaSR) and that its activation induces inflammatory cytokine production. Also, its expression is enhanced ...
    • BONE EXTRACELLULAR MATRIX STIMULATES INVASIVENESS OF ESTROGEN-RESPONSIVE HUMAN MAMMARY MCF-7 CELLS 
      Martínez Winkler, Jorge; Fuentes, Mauricio; Cambiazo Ayala, Liliana; Santibáñez, J. Francisco (WILEY-LISS, DIV JOHN WILEY & SONS INC, 1999-10-08)
      Bone is the most frequent site of metastasis in breast cancer. This causes destructive osteolytic lesions. To achieve metastasis to bone, breast cancer cells must proliferate in a new microenvironment, arrest on ...
    • Effects of platelet-rich and -poor plasma on the reparative response of gingival fibroblasts 
      Cáceres, Mónica; Martínez, Constanza; Martínez Winkler, Jorge; Smith, Patricio (2012)
      Objectives: Although platelet-rich plasma (PRP) has been proposed as a therapeutic tool to enhance wound repair, the cellular and molecular mechanisms stimulated by this agent are still not completely understood. The ...
    • EGF receptor transactivation by urokinase receptor stimulus through a mechanism involving Src and matrix ... 
      Guerrero, Javier; Santibáñez, Juan Francisco; González, Alfonso; Martínez Winkler, Jorge (Elsevier Inc., 2004)
      Urokinase-type plasminogen activator receptor (uPAR) and epidermal growth factor receptor (EGFR) are ubiquitous receptors involved in the control of a variety of cellular processes frequently found altered in cancer cells. ...
    • Prostate-Derived Soluble Factors Block Osteoblast Differentiation in Culture 
      Martínez Winkler, Jorge; Silva, Sofía; Santibáñez, Juan Francisco (WILEY-LISS, DIV JOHN WILEY & SONS INC, 1996-04)
      Bone metastasis is a common event and a major cause of morbidity in prostate cancer patients. After colonization of bone, prostate cells induce an osteoblastic reaction which is not associated with marrow fibrosis ...
    • Soluble factors derived from tumor mammary cell lines induce a stromal mammary adipose reversion in human ... 
      Guerrero, Javier; Tobar, Nicolás; Cáceres, Mónica; Espinoza, Lorena; Escobar Oliva, Paula; Dotor, Javier; Smith, Patricio C.; Martínez Winkler, Jorge (Springer Science+Business Media, 2011)
      In carcinomas such as those of breast, pancreas, stomach, and colon, cancer cells support the expansion of molecular and cellular stroma in a phenomenon termed desmoplasia, which is characterized by a strong fibrotic response. ...