Browsing by Author "Santos, José Luis"

Now showing items 1-15 of 15

    • Asociación entre la conducta alimentaria y polimorfismos genéticos de la leptina y su receptor en niños ... 
      Valladares, Macarena; Obregón, Ana María; Weisstaub Nuta, Sergio; Burrows, Raquel; Patiño, Ana; Ho Urriola, Judith; Santos, José Luis (SENPE, 2015)
      Introducción: La leptina (LEP) se produce principalmente en el tejido adiposo y actúa en el hipotálamo regulando la ingesta energética. Mutaciones en el gen LEP o en su receptor (LEPR) que generen obesidad monogénica son ...
    • The association between HLA DQ genetic polymorphism and type 1 diabetes in a case-parent study conducted ... 
      Mimbacas, Adriana; Pérez Bravo, Fernando; Santos, José Luis; Pisciottano, Carmen; Grignola, Rosario; Javiel, Gerardo; Jorge, Ana María; Cardoso, Horacio (KLUWER ACADEMIC PUBL, 2004-10)
      Susceptibility to the type 1 diabetes is genetically controlled and there is an increased risk associated with the presence of some specific alleles of the human leukocyte antigens class II loci (DQA1 and DQB1 genes). The ...
    • Association between obesity and insulin resistance with UCP2–UCP3 gene variants in Spanish children and adolescents 
      Ochoa, María C.; Santos, José Luis; Azcona, Cristina; Moreno Aliaga, María J.; Martínez González, Miguel A.; Martínez, J. Alfredo; Marti, Amelia (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2007-12)
      A number of studies have yielded controversial results on the association between polymorphisms in UCP2 and UCP3 genes with obesity and its comorbidities. The discrepancy among studies might be partially explained by the ...
    • Indicadores antropométricos, composición corporal y limitaciones funcionales en ancianos 
      Arroyo Albala, Patricia; Lera Marques, Lydia; Sánchez, Hugo; Bunout Barnett, Daniel; Santos, José Luis; Albala Brevis, Cecilia (Sociedad Médica de Santiago, 2007-07)
      Functional limitations limit the independence and jeopardize the quality of life of elderly subjects. Aim: To assess the association between anthropometric measures and body composition with functional limitations in ...
    • Insulin secretion in women who have polycystic ovary syndrome and carry the Gly972Arg variant of insulin ... 
      Sir Petermann, Lidia; Ángel Badillo, Bárbara; Maliqueo Yevilao, Manuel; Santos, José Luis; Riesco, María Virginia; Toloza, Henry; Pérez Bravo, Francisco (ELSEVIER, 2004-10)
      OBJECTIVE: We evaluated metabolic parameters in Chilean women with polycystic ovary syndrome (PCOS) who were carriers and non-carriers of the glycine-to-arginine substitution at codon 972 (Gly972Arg) variant of insulin ...
    • Intestinal FABP2 A54T polymorphism: Association with insulin resistance and obesity in women 
      Albala Brevis, Cecilia; Santos, José Luis; Cifuentes, Mariana; Villarroel, Ana C.; Lera Marques, Lydia; Liberman Guendelman, Claudio; Ángel Badillo, Bárbara; Pérez Bravo, Francisco (NORTH AMER ASSOC STUDY OBESITY, 2004-02)
      Objective: To assess the association between the Ala54Thr genetic polymorphism of the fatty acid-binding protein 2 (FABP2) gene with insulin resistance and obesity. Research Methods and Procedures: According to a sampling ...
    • Melanocortin-4 receptor polymorphism rs17782313: Association with obesity and eating in the absence of ... 
      Ho Urriola, Judith; Guzmán Guzmán, Iris P; Smalley, Susan V.; González, Andrea; Weisstaub Nuta, Sergio; Domínguez Vásquez, Patricia; Valladares, Macarena; Amador, Paola; Hodgson, María Isabel; Obregón, Ana M.; Santos, José Luis (Elsevier, 2014)
      Objective: The aim of this study was to assess the association between melanocortin-4 receptor (MC4R) rs17782313 alleles with obesity and eating behavior scores in Chilean children. Methods: A case–control study was ...
    • Niveles plasmáticos de citoquinas IL-1, IL2 e IL-4 en niños diabéticos tipo 1 de diagnóstico reciente y su ... 
      Pérez Bravo, Francisco; Oyarzún, Amaya; Carrasco Piña, Elena; Ángel Badillo, Bárbara; Albala Brevis, Cecilia; Santos, José Luis (SOC MEDICA SANTIAGO, 2004-04)
      Background: Type 1 diabetes is an organ specific autoimmune disease whose incidence is increasing worldwide. A functional imbalance in cytokine production resulting in dominance of T helper (Th1) over Th2-type response has ...
    • No Evidence for an Association Between Genetic Polymorphisms of 
      Santos, José Luis; Pérez Bravo, Francisco; Martínez, J. A.; Montalvo, Domingo; Albala Brevis, Cecilia; Carrasco, Elena (Elsevier Science Inc., 2002)
      OBJECTIVE: We assessed the association between Gln27Glu and Trp64Arg genetic polymorphisms of the 2 (ADRB2) and 3 (ADRB3) adrenergic receptor genes with body mass index and other cardiovascular risk factors. METHODS: ...
    • No evidence of association between the serotonin 2A receptor 21438G/Apromoter polymorphism and childhood ... 
      Santos, José Luis; Ochoa, María C.; Patiño, A.; Azcona, C.; Martínez, J. A.; Marti, A. (TAYLOR & FRANCIS, 2005-08)
      Serotonin has been related to feeding behaviour and body weight control through its suppressive effect on appetite. Conflicting results have been published in the literature regarding the association between the -1438 G/A ...
    • Predictive equations for stature in the elderly: A study in three Latin American cities 
      Lera Marques, Lydia; Santos, José Luis; García Ghiringheli, Carola; Arroyo Albala, Patricia; Albala Brevis, Cecilia (TAYLOR & FRANCIS LTD, 2005-11)
      Aim: The aim of this study was to develop predictive equations based on anthropometric data to estimate stature in people 60 years and older in Latin America. Design: Population-based cross-sectional study in three Latin ...
    • Prevalence of metabolic syndrome in obese Chilean children and association with gene variants of the ... 
      Suazo, José; Hodgson, María Isabel; Obregón, Ana María; Valladares, Macarena; Weisstaub Nuta, Sergio; Amador, Paola; Santos, José Luis (2013)
      Metabolic syndrome (MS) related to adult type 2 diabetes mellitus and cardiovascular disease is prevalent among obese children/adolescents. Genetic variants of the leptin-melanocortin system have been associated ...
    • Prevalence of type 2 diabetes and obesity in two Chilean aboriginal populations living in urban zones 
      Carrasco Piña, Elena; Pérez Bravo, Francisco; Ángel Badillo, Bárbara; Albala Brevis, Cecilia; Santos, José Luis; Larenas Y., Gladys; Montalvo V., Domingo (SOC MEDICA SANTIAGO, 2004-10)
      Background: The prevalence of cardiovascular risk factors is increasing in aboriginal populations in Chile. Aim: To study the prevalence of obesity, type 2 diabetes and serum lipids in two aboriginal populations, Mapuche ...
    • VDR polymorphisms influence the immune response in type 1 diabetic children from Santiago, Chile 
      García, Diego; Ángel Badillo, Bárbara; Carrasco, Elena; Albala Brevis, Cecilia; Santos, José Luis; Pérez Bravo, Francisco (ELSEVIER IRELAND LTD, 2007-07)
      Objective: To evaluate the influence of ApaI, BsmI and TaqI polymorphisms of the VDR gene and HLA-DQB1* alleles in type 1 diabetic children and to assess their possible relationship with circulating levels of 25-hydroxyvitamin ...
    • Vitamin D receptor polymorphism and susceptibility to type 1 diabetes in chilean subjects: A case-parent study 
      Ángel Badillo, Bárbara; Santos, José Luis; Carrasco Piña, Elena; Albala Brevis, Cecilia; Pérez Bravo, Francisco (SPRINGER, 2004)
      Several reports have found a relation between polymorphisms of the vitamin D receptor gene (VDR) and the development of type I diabetes. We have examined the association of three VDR polymorphism with type I diabetes in ...