Group electrophilicity as a model of nucleofugality in nucleophilic substitution reactions
Author | dc.contributor.author | Campodónico, Paola R. | |
Author | dc.contributor.author | Aizman, Arie | es_CL |
Author | dc.contributor.author | Contreras Ramos, Renato | es_CL |
Admission date | dc.date.accessioned | 2008-12-15T16:01:03Z | |
Available date | dc.date.available | 2008-12-15T16:01:03Z | |
Publication date | dc.date.issued | 2006-05-10 | |
Cita de ítem | dc.identifier.citation | CHEMICAL PHYSICS LETTERS Volume: 422 Issue: 4-6 Pages: 340-344 Published: MAY 10 2006 | en |
Identifier | dc.identifier.issn | 0009-2614 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/118767 | |
Abstract | dc.description.abstract | We propose and test an empirical nucleofugality index to rank the leaving group ability of a series of molecular fragments present in nucleophilic substitution reactions of carbonyl and thiocarbonyl derivatives. The nucleofugality index is defined as the group electrophilicity of the leaving group embedded in the substrate that undergoes the nucleophilic attack. The reliability and usefulness of this new reactivity index is tested against experimental kinetic data. | en |
Lenguage | dc.language.iso | en | en |
Publisher | dc.publisher | ELSEVIER | en |
Keywords | dc.subject | STRUCTURE-REACTIVITY CORRELATIONS | en |
Título | dc.title | Group electrophilicity as a model of nucleofugality in nucleophilic substitution reactions | en |
Document type | dc.type | Artículo de revista |
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