| Author | dc.contributor.author | Gómez Jeria, Juan | |
| Author | dc.contributor.author | Sotomayor, P. | es_CL |
| Admission date | dc.date.accessioned | 2011-11-10T20:45:58Z | |
| Available date | dc.date.available | 2011-11-10T20:45:58Z | |
| Publication date | dc.date.issued | 1988 | |
| Cita de ítem | dc.identifier.citation | THEOCHEM-JOURNAL OF MOLECULAR STRUCTURE, Volume: 43, Pages: 493-498, 1988 | es_CL |
| Identifier | dc.identifier.issn | 0166-1280 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/119359 | |
| General note | dc.description | Artículo de publicación ISI | es_CL |
| Abstract | dc.description.abstract | A Quantitative Structure-Activity Relationship study for a group of opiates
interacting with the mu receptor was carried out. The study consisted in searching
a relationship between the drug-receptor equilibrium constant and steric/
electronic structure factors. Several equations were obtained and analyzed. It
is possible to conclude from this study that if all the experimental values correspond
only to the interaction with the mu receptor, then the hypothesis of a
comben skeleton interacting with the mu receptor cannot be supported. | es_CL |
| Patrocinador | dc.description.sponsorship | This work has received financial support from University of Chile (Project
Q-2442) and from UNESCO (Project 6267). We thank Dr.Julia Parra-Mouchet for
helpful comments. | es_CL |
| Lenguage | dc.language.iso | en | es_CL |
| Publisher | dc.publisher | ELSEVIER SCIENCE BV | es_CL |
| Título | dc.title | QUANTUM CHEMICAL STUDY OF ELECTRONIC-STRUCTURE AND RECEPTOR-BINDING IN OPIATES | es_CL |
| Document type | dc.type | Artículo de revista | |
