| Author | dc.contributor.author | Cassels Niven, Bruce | es_CL |
| Author | dc.contributor.author | Herreros, S. | es_CL |
| Author | dc.contributor.author | Ibáñez, C. | es_CL |
| Author | dc.contributor.author | Rozende, M. C. | es_CL |
| Author | dc.contributor.author | Sebastián, C. | |
| Author | dc.contributor.author | Sepúlveda, S. | es_CL |
| Admission date | dc.date.accessioned | 2012-08-09T21:32:33Z | |
| Available date | dc.date.available | 2012-08-09T21:32:33Z | |
| Publication date | dc.date.issued | 1981-12 | |
| Cita de ítem | dc.identifier.citation | Anales Asoc. Quím. Argentina , 70, 283-288, 1982. | es_CL |
| Identifier | dc.identifier.issn | 0365-0375 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/119551 | |
| Abstract | dc.description.abstract | l-Aryl-2-nitroalkenes can. ba synthesized mest convéniently by refluxing
aromatic aidehydes with nitromethane 01' nitroethane in acetic acid using n-butyla
llIineas a catalyst •.{ In this way' seventeen nev cOIIl'PC'lmdosf this type aad seve-raI
known ana10gues withalkaxy andhalo ring substituents ware prepared. without the
CODcurrent production ol the corref5l'011dingly' substituted benzonitrii_. Moat of
thes!! compounds were- tested in theP-J88 murine 1ympbocytic leuk.emia aseay; {QUr
of them pc~s_sed reproducible antitumor activity, and another five gav& si~ficantiy
increased survival times wtri.ch _re not rept'Oduced | es_CL |
| Patrocinador | dc.description.sponsorship | Este trabajo se realizó con el financiamiento de DICYT (USACH). | es_CL |
| Lenguage | dc.language.iso | es | es_CL |
| Publisher | dc.publisher | Asoc. Quím. Argentina | es_CL |
| Título | dc.title | SINTESIS DE 1-ARIL-2-NITROALQUENOS ANTITUMORALES | es_CL |
| Document type | dc.type | Artículo de revista | |
