| Author | dc.contributor.author | Pessoa Mahana, David | |
| Author | dc.contributor.author | Núñez, Andrés | es_CL |
| Author | dc.contributor.author | Espinosa Bustos, Christian | es_CL |
| Author | dc.contributor.author | Mella Raipán, Jaime A. | es_CL |
| Author | dc.contributor.author | Pessoa Mahana, Hernán | es_CL |
| Admission date | dc.date.accessioned | 2010-06-30T19:02:02Z | |
| Available date | dc.date.available | 2010-06-30T19:02:02Z | |
| Publication date | dc.date.issued | 2010 | |
| Cita de ítem | dc.identifier.citation | J. Braz. Chem. Soc., Vol. 21, No. 1, 63-70, 2010. | en_US |
| Identifier | dc.identifier.issn | 0103 - 5053 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/121015 | |
| Abstract | dc.description.abstract | The synthesis of a series of substituted arylpiperazines linked to a 2-(pyridin-3-yl)-1H-benzo[d]imidazole scaffold through an alkylic linker is reported. The novel 1-(2-(4-arylpiperazin-1-yl)alkyl)-2-(pyridin-3-yl)-1H-benzimidazole derivatives are structurally related to the anti-HIV-1 drug Delavirdine and belong to the bis(heteroaryl)piperazines family (BHAPs), a well known HIV-1 reverse transcriptase inhibitors group. | en_US |
| Patrocinador | dc.description.sponsorship | This work was supported by VRAID (grant No. 01/2008). | en_US |
| Lenguage | dc.language.iso | en | en_US |
| Keywords | dc.subject | arylpiperazinyl derivatives | en_US |
| Título | dc.title | Synthesis of a Novel Series of 4-Arylpiperazinyl Derivatives Linked to a 2-(Pyridin-3-yl)-1H-benzimidazole as New Delavirdine Analogues | en_US |
| Document type | dc.type | Artículo de revista | |
