The synthesis of C-2 symmetry diesters of (3R,4R)-TTFOL through a green and stereoselective (2R,3R)-TADDOL rearrangement
| Author | dc.contributor.author | Costantino, Andrea R. | |
| Author | dc.contributor.author | Montiel Schneider, María Gabriela | |
| Author | dc.contributor.author | Galdámez Silva, Antonio | |
| Author | dc.contributor.author | Ocampo, Romina A. | |
| Author | dc.contributor.author | Mandolesi, Sandra D. | |
| Author | dc.contributor.author | Koll, Liliana C. | |
| Admission date | dc.date.accessioned | 2016-01-12T15:15:27Z | |
| Available date | dc.date.available | 2016-01-12T15:15:27Z | |
| Publication date | dc.date.issued | 2015 | |
| Cita de ítem | dc.identifier.citation | Tetrahedron: Asymmetry 26 (2015) 1341–1347 | en_US |
| Identifier | dc.identifier.other | DOI: 10.1016/j.tetasy.2015.10.014 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/136400 | |
| General note | dc.description | Artículo de publicación ISI | en_US |
| Abstract | dc.description.abstract | An efficient, green, and atom economic methodology for the stereoselective synthesis of C-2 symmetry (3R,4R)-TTFOL diester derivatives has been developed. The procedure occurs through a (2R,3R)-TADDOL dioxolane cleavage and rearrangement under mild conditions by its reaction with a carboxylic acid in the presence of TFAA/H3PO4 without the need for an inert atmosphere to give generally high yields. | en_US |
| Patrocinador | dc.description.sponsorship | ANPCyT (Capital Federal, Argentina/BID, PICT project) 2644 CONICET (Buenos Aires, Argentina, PIP project) 112-201101-00828 Universidad Nacional del Sur (Bahia Blanca, Argentina) PGI 24/Q041 | en_US |
| Lenguage | dc.language.iso | en | en_US |
| Publisher | dc.publisher | Elsevier | en_US |
| Type of license | dc.rights | Atribución-NoComercial-SinDerivadas 3.0 Chile | * |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | * |
| Keywords | dc.subject | Integrase inhibitors | en_US |
| Keywords | dc.subject | Carboxylic-acids | en_US |
| Keywords | dc.subject | In-situ | en_US |
| Keywords | dc.subject | Taddol | en_US |
| Keywords | dc.subject | Derivatives | en_US |
| Keywords | dc.subject | Ligands | en_US |
| Keywords | dc.subject | Analogs | en_US |
| Keywords | dc.subject | Esters | en_US |
| Keywords | dc.subject | Esterification | en_US |
| Keywords | dc.subject | Anhydrides | en_US |
| Título | dc.title | The synthesis of C-2 symmetry diesters of (3R,4R)-TTFOL through a green and stereoselective (2R,3R)-TADDOL rearrangement | en_US |
| Document type | dc.type | Artículo de revista |
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Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 Chile