Histologic types of breast carcinoma in relation to international variation and breast cancer risk factors
Author
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Holck, S.
Author
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Stalsberg, H.
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Thomas, D. B.
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Noonan, E. A.
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Berry, G.
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Maclennan, R.
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Shearman, R.
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Jelihovsky, T.
Author
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Booth, J. Cooper
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Molina, R.
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Martinez, L.
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Salas, O.
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Dabancens, A.
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Zhiheng, Chen
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Yun, Tao
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Wei, Hu Yong
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Cuadros, A.
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Aristizabal, N.
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Ebeling, K.
Author
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Nishan, P.
Admission date
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2018-12-20T14:08:25Z
Available date
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2018-12-20T14:08:25Z
Publication date
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1989
Cita de ítem
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International Journal of Cancer, Volumen 44, Issue 3, 2018, Pages 399-409
Identifier
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10970215
Identifier
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00207136
Identifier
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10.1002/ijc.2910440304
Identifier
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https://repositorio.uchile.cl/handle/2250/154222
Abstract
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Associations between breast cancer risk factors and histologic types of invasive breast carcinoma were studied in 2,728 patients. Lobular and tubular carcinomas occurred with increased relative frequency in most high‐risk groups. The proportion of these types increased with age to a maximum at 45–49 years and decreased in the following decade. Significantly increased proportions of lobular and tubular carcinomas were also associated with high‐risk countries, prior benign breast biopsy, bilateral breast cancer, concurrent mammary dysplasia, high age at first live birth, never‐pregnant patients compared to those with a first live birth before age 20, private pay status, and length of education. Nonsignificant increases were associated with family history of breast cancer, less than 5 live births, less than 25 months total of breast feeding, use of oral contraceptives or IUD, and high occupational class. As a general trend, the higher the overall relative risk, the higher the proportion o