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Synthesis and evaluation of the trypanocydal activity of 4- alkylamino-6-nitroquinolines

Authordc.contributor.authorTapia, Ricardo A. 
Authordc.contributor.authorPrieto, Yolanda 
Authordc.contributor.authorZamora, Gaston 
Authordc.contributor.authorMorello Casté, Antonio 
Authordc.contributor.authorRepetto Scaramelli, Yolanda 
Admission datedc.date.accessioned2018-12-20T15:04:40Z
Available datedc.date.available2018-12-20T15:04:40Z
Publication datedc.date.issued2000
Cita de ítemdc.identifier.citationHeterocyclic Communications, Volumen 6, Issue 6, 2018, Pages 539-544
Identifierdc.identifier.issn07930283
Identifierdc.identifier.other10.1515/HC.2000.6.6.539
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/157581
Abstractdc.description.abstractA straightforward synthesis of a group of 4-alkylamino-6-nitroquinolines starting from a common intermediate, 5,8-dimethoxy-6-nitro-4(1H)quinolone 3, is described. These compounds were tested in vitro as potential anti-trypanosomal agents. Some derivatives were found to have a significant activity, but less efficient than the control drug.
Lenguagedc.language.isoen
Publisherdc.publisherFreund Publishing House Ltd
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceHeterocyclic Communications
Keywordsdc.subjectOrganic Chemistry
Títulodc.titleSynthesis and evaluation of the trypanocydal activity of 4- alkylamino-6-nitroquinolines
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile