Determination of nitrendipine with β-cyclodextrin modified carbon paste electrode

Abstract

Carbon paste electrodes modified with β-cyclodextrin have been investigated for voltammetric determination of nitrendipine. The immobilization of the β-cyclodextrin on the carbon paste leads to a modification of the electrode surface that causes a significant increase in the peak current of the nitrendipine reduction, probably due to formation of an inclusion complex between β-cyclodextrin and nitrendipine. This property was used with analytical purposes by developing a stripping differential pulse voltammetric (SDPV) method to determine nitrendipine.