Calcium & ROS: two orchestra directors for the requiem of death
| Author | dc.contributor.author | San Martín Rovirosa, Carol | |
| Author | dc.contributor.author | Böhme, Daniela | |
| Author | dc.contributor.author | Rojas Rivera, Diego | |
| Admission date | dc.date.accessioned | 2020-06-03T14:42:29Z | |
| Available date | dc.date.available | 2020-06-03T14:42:29Z | |
| Publication date | dc.date.issued | 2020 | |
| Cita de ítem | dc.identifier.citation | Cell Calcium 85 (2020) 102113 | es_ES |
| Identifier | dc.identifier.other | 10.1016/j.ceca.2019.102113 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/175168 | |
| Abstract | dc.description.abstract | Tumor necrosis factor alpha (TNF) triggers regulated necrosis of mycobacterium-infected macrophages through of mitochondrial reactive oxygen species (mitoROS) production in a RIPK1/3-dependent manner. To explain that, Roca and colleagues describe an inter-orgallenar circuit which involves the lysosomal ceramide production, mitoROS, BAX activation and RyR Ca2+ efflux from the endoplasmic reticulum into the mitochondrion. | es_ES |
| Patrocinador | dc.description.sponsorship | Comisión Nacional de Investigación Científica y Tecnológica (CONICYT), CONICYT FONDECYT: 11180546, 1191003, 11171061, 1190958. | es_ES |
| Lenguage | dc.language.iso | en | es_ES |
| Publisher | dc.publisher | Elsevier | es_ES |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | * |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | * |
| Source | dc.source | Cell Calcium | es_ES |
| Keywords | dc.subject | TNF | es_ES |
| Keywords | dc.subject | Mycobacterium tuberculosis | es_ES |
| Keywords | dc.subject | Calcium | es_ES |
| Keywords | dc.subject | ROS | es_ES |
| Keywords | dc.subject | Ryanodine receptor | es_ES |
| Keywords | dc.subject | Regulated necrosis | es_ES |
| Título | dc.title | Calcium & ROS: two orchestra directors for the requiem of death | es_ES |
| Document type | dc.type | Artículo de revista | es_ES |
| dcterms.accessRights | dcterms.accessRights | Acceso Abierto | |
| Cataloguer | uchile.catalogador | rvh | es_ES |
| Indexation | uchile.index | Artículo de publicación ISI | |
| Indexation | uchile.index | Artículo de publicación SCOPUS |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile