Browsing by Author "01d3cf37-f82b-429d-9bd7-e8d47201c92d"

Now showing items 1-7 of 7

    • Amphetamine derivatives as Monoamine Oxidase Inhibitors 
      Reyes Parada, Miguel; Iturriaga Vásquez, Patricio; Cassels Niven, Bruce (Frontiers Media, 2020)
      Amphetamine and its derivatives exhibit a wide range of pharmacological activities, including psychostimulant, hallucinogenic, entactogenic, anorectic, or antidepressant effects. The mechanisms of action underlying these ...
    • Editorial: celebrating 40 years of the chilean society of pharmacology 
      Yévenes, Gonzalo E.; Bravo, Javier A.; Díaz Araya, Guillermo; Sotomayor Zárate, Ramón; Fiedler Temer, Jenny; Reyes Parada, Miguel; Fuentealba, Jorge (Frontiers Media, 2020)
    • Monoamine Oxidase Inhibitory Properties of Some Methoxylated and Alkylthio Amphetamine Derivatives ... 
      Scorza, Ma. Cecilia; Carrau, Cecilia; Silveira, Rodolfo; Zapata-Torres, Gerald; Cassels Niven, Bruce; Reyes Parada, Miguel (Elsevier Science Inc., 1997)
      The monoamine oxidase (MAO) inhibitory propenies of a series of amphetamine derivatives with difTerent substituents at or around rhe para position of the aromaric ring were evaluateJ. i¡, in viero stuJies in which a crude ...
    • Nicotinic antagonist UFR2709 inhibits nicotine reward and decreases anxiety in zebrafish 
      Viscarra, Franco; González Gutiérrez, Juan; Esparza, Erica; Figueroa, Carla; Paillali, Pablo; Hödar Salazar, Martín; Céspedes, Camilo; Quiroz, Gabriel; Sotomayor Zárate, Ramón; Reyes Parada, Miguel; Bermúdez, Isabel; Iturriaga-Vásquez, Patricio (MDPI, 2020)
      Zebrafish is becoming a popular animal model in neuropharmacology and drug discovery, mainly due to its ease of handling and low costs involved in maintenance and experimental work. This animal displays a series of complex ...
    • PRELlMINARY VOLTAMMETRIC DATA FOR THE OXIDATION OF 4-METHYLAMINOPHENETHYLAMINE DERIVATIVES IN BUFFER AND ... 
      Rojas, Evelyn; Norambuena, Ester; Olea Azar, Claudio; Reyes Parada, Miguel; Cassels Niven, Bruce (Sociedad Chilena de Química, 1993-10-15)
      The electrochemistry 01 a series 01 monoamine oxidase-inhibitory 4-Nmethyl and N,N-dimethylaminophenethylamines was studied using cyclic voltammetry. Electron transler was irreversible both in aqueous buffer.(pH = 7.4) and ...
    • Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin ... 
      Cerda Cavieres, Christopher David; Quiroz, Gabriel; Iturriaga-Vásquez, Patricio; Rodríguez Lavado, Julio; Alarcón Espósito, Jazmín; Saitz Barría, Claudio; Pessoa Mahana, Carlos D.; Chung, Hery; Araya Maturana, Ramiro; Mella Raipán, Jaime A.; Cabezas, David; Ojeda Gómez, Claudia; Reyes Parada, Miguel; Pessoa Mahana, Hernán (MDPI, 2020)
      A series of 27 compounds of general structure 2,3-dihydro-benzo[1,4]oxazin-4-yl)-2-{4-[3-(1H-3indolyl)-propyl]-1-piperazinyl}-ethanamides, Series I: 7(a-o) and (2-{4-[3-(1H-3-indolyl)-propyl]-1-piperazinyl}-acetylamine)- ...
    • Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines ... 
      Rodríguez Lavado, Julio; Gallardo Garrido, Carlos; Mallea Catalán, Michael; Bustos, Víctor; Osorio, Rodrigo; Hödar Salazar, Martín; Chung, Hery; Araya Maturana, Ramiro; Lorca, Marcos; Pessoa Mahana, C. David; Mella Raipán, Jaime; Saitz Barría, Claudio; Jaque Olmedo, Pablo; Reyes Parada, Miguel; Iturriaga-Vásquez, Patricio; Pessoa Mahana, Hernán (Elsevier, 2020)
      During the last decade, the one drug-one target strategy has resulted to be inefficient in facing diseases with complex ethiology like Alzheimer's disease and many others. In this context, the multitarget paradigm has ...