Browsing by Author "201-0010590"
Now showing items 1-20 of 68
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(AMER CHEMICAL SOC, 2005-03)We report a new and specific mechanism for iron-mediated neurotoxicity using RCHT cells, which were derived from rat hypothalamus. RCHT cells exhibit immunofluorescent-positive markers for dopamine beta-hydroxylase and the ...
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(PERGAMON-ELSEVIER, 2008-11-15)The present study investigated the redox-consequences of the interaction between various endogenous thiols (RSH)-glutathione, cysteine, homocysteine, c-glutamyl-cysteine, and cysteinyl-glycine-and Cu2+ ions, in terms of ...
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(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2009-12)In the search of new therapeutic tools for the treatment of American Trypanosomiasis, the largest parasitic disease burden in the American continent, three series of novel ruthenium complexes of the formula [RuCl2(HL)(2)], ...
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(Wiley-VCH Verlag, 2014)Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major health problem worldwide. In this work, we report the development of palladium and platinum metal complexes with 5-nitrofuryl-containing ...
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(PERGAMON-ELSEVIER SCIENCE LTD, 2005-10)Cyclic voltammetry and electron spin resonance (ESR) techniques were used in the investigation of several potential antiprotozoal thiosemicarbazones nitrofurane derivatives. A self-protonation process involving the ...
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(PERGAMON-ELSEVIER SCIENCE LTD, 2003-01-01)The electron spin resonance (ESR) spectra of free radicals obtained by electrolytic or microsomal reduction of several potential antiprotozoal 1,2,5-oxadiazoles were characterized and analyzed. Ab initio molecular orbital ...
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(HARWOOD ACAD PUBL GMBH, 2000)This paper deals with the reactivity of the nitro radical anion electrochemically generated from nitrofurantoin with glutathione. Cyclic voltammetry (CV) and controlled potential electrolysis were used to generate the nitro ...
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(PERGAMON-ELSEVIER SCIENCE LTD, 2001-08)The ESR spectra of radicals obtained by electrolytic reduction of 4,4-dimethylanthracene- 1,9,10 (4H)-trione (1) and the regioisomeric quinones 8-acetyloxymethyl-4,4,5-trimethyl- (2), and 5-acetyloxy-methyl-4,4,8-trimeth ...
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(SOCIEDAD CHILENA DE QUIMICA, 2002-09)Acrylamide can be polymerized using new catalytic systems. These are based on rhenium complexes as photosensitizers with triethylamine (TEA). Electron Spin Resonance (ESR) was used for the detection of radicals species ...
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(PERGAMON-ELSEVIER SCIENCE LTD, 2005-07)The ESR spectra of radicals obtained by electrolytic reduction of 2-acylpyridines and 6,6'-diacyl-2,2'-bipyridines were measured in dimethylsulfoxide (DMSO) and analyzed by quantum chemical calculations. The electrochemistry ...
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(ELSEVIER, 2010)Two families of 5-nitroindazole derivatives were electrochemically studied in an aprotic solvent using cyclic voltammetry (CV) technique. The produced nitro-anion radical species were characterized using electron spin ...
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(PERGAMON-ELSEVIER SCIENCE LTD, 2006-01)The electrochemistry of 3-alkoxy- and 3-hydroxy-1-[(omega-(dialkylamino)alkyl]-5-nitroindazole derivatives were characterized using cyclic voltammetry in DMSO. The nitro reduction process was studied and this was affected ...
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(SOCIEDAD CHILENA DE QUIMICA, 2003-12)The Electron Spin Resonance (ESR) spectra of radicals obtained from two new potential antitrypanosomal drugs by Trypanosoma cruzi reduction were analyzed. DMPO Spin Trapping was used to investigate the possible formation ...
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(TAYLOR & FRANCIS LTD, 2003-08)Electron spin resonance (ESR) spectra of radicals obtained from two analogues of the antiprotozoal drug nifurtimox by electrolytic and Trypanosoma cruzi reduction were analyzed. The electrochemistry of these compounds was ...
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(Elsevier B.V., 2008-11)The electron spin resonance (ESR) spectra of free radicals obtained by electrolytic reduction of triazolopyridyl pyridyl ketones and dipyridyl ketones derivatives were measured in dimethylsulfoxide (DMSO). The hyperfine ...
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(Elsevier B.V., 2008-08)Cyclic voltammetry (CV) and electron spin resonance (ESR) techniques were used in the investigation of novel palladium complexes with bioactive thiosemicarbazones derived from 5-nitrofurane or 5-nitrofurylacroleine. Sixteen ...
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(PERGAMON-ELSEVIER SCIENCE LTD, 2011-03)Electrochemical and ESR studies were carried out in this work with the aim of characterizing the reduction mechanisms of 4-substituted and 1,4-disubstituted 7-nitroquinoxalin-2-ones by means of cyclic voltammetry in DMSO ...
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(Universidad de Chile, 2011)El estudio de la diferenciación enantiomérica de complejos diasteroisoméricos flavanona/ciclodextrina, formados específicamente por la mezcla racémica de (±)-flavanona, (±)-4’-hidroxiflavanona y (±)-2’-hidroxiflavanona, ...
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(Universidad de Chile, 2007)En esta tesis se estudiaron las características fisicoquímicas de los complejos de inclusión de cuatro flavonoides, quercetina, morina, catequina y galangina con diferentes ciclodextrinas, (βciclodextrina, 2-hidroxipro ...
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(Springer, 2018)To face the high costs of developing new drugs, researchers in both industry and academy are looking for ways to repurpose old drugs for new uses. In this sense, bisphosphonates that are clinically used for bone diseases ...
