Browsing by Author "201-0432762"
Now showing items 1-20 of 49
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(American Association of Immunologists, 2004)Tumor cells treated with IL-10 were shown to have decreased, but peptide-inducible expression of MHC class I, decreased sensitivity to MHC class I-restricted CTL, and increased NK sensitivity. These findings could be ...
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(2011)We have previously demonstrated that IT9302, a nonameric peptide homologous to the C-terminal domain of human IL-10, mimics several effects of the cytokine including down-regulation of the antigen presentation machinery ...
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(Lippicott Williams & Wilkins, 2016-04)
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(2011)The aim of this work was to study the effect of anti-TNF treatment on CD4+ Th1, Th17 and regulatory T cells (Tregs), together with CD8+ T cells and NK cells from rheumatoid arthritis (RA) patients. For this purpose, 18 RA ...
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(2005)Objective. To assess the enzymatic activity and biochemical status of dipeptidyl peptidase IV (DPP IV), an enzyme that participates in the degradation of proinflammatory molecules, in sera from a group of patients with ...
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(Nature, 2020)Large genome-wide association studies (GWAS) have increased our knowledge of the genetic risk factors of rheumatoid arthritis (RA). However, little is known about genetic susceptibility in populations with a large admixture ...
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(American College of Rheumatology, 2013)Objective. Dendritic cells (DCs) modulated with lipopolysaccharide (LPS) are able to reduce inflammation when therapeutically administered into mice with collagen-induced arthritis (CIA). The aim of this study was to ...
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(2013)Objective Dendritic cells (DCs) modulated with lipopolysaccharide (LPS) are able to reduce inflammation when therapeutically administered into mice with collagen-induced arthritis (CIA). The aim of this study was to uncover ...
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(Blackwell, 2008)Background and aims: Periodontitis is an infection with an episodic nature of tissue support destruction. The aim of this work was to determine the levels of chemokines, cytokines, matrix metalloproteinase-13, periodontal ...
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Clinical parameters and biomarkers for anti-TNF treatment prognosis in rheumatoid arthritis patients (International League of Associations for Rheumatology (ILAR), 2014)Tumor necrosis factor (TNF) plays a pivotal role in the pathogenesis of rheumatoid arthritis (RA). This finding has led to the development of TNF blockers for RA treatment. However, response to these therapies is ...
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(ELSEVIER, 2006)Tumour necrosis factor (TNF), a cytokine mainly produced by macrophages, is associated with a broad spectrum of biological effects, mainly associated with the host defense against microbes. The TNF gene Is located on ...
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(Universidad de Chile, 2011)La biotecnología ha adquirido un rol fundamental en la industria de producción de biofármacos, la cual ofrece nuevas alternativas para el tratamiento de diversas enfermedades. Entre los más utilizados están los anticuerpos ...
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(Frontiers Media SA, 2017)There is growing interest in the use of tolerogenic dendritic cells (tolDCs) as a potential target for immunotherapy. However, the molecular bases that drive the differentiation of monocyte-derived DCs (moDCs) toward a ...
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(Frontiers Media, 2016)Tolerogenic dendritic cells (DCs) are a promising tool to control T cell-mediated autoimmunity. Here, we evaluate the ability of dexamethasone-modulated and monophosphoryl lipid A (MPLA)-activated DCs [MPLA-tolerogenic DCs ...
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(2013)Background. Pharmacologically modulated dendritic cells (DCs) have been shown to restore tolerance in type II collagen- (CII-) induced arthritis (CIA). We examined the effect of dexamethasone (DXM) administration as a ...
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(2013)A new paradigm has emerged relating the pathogenesis of rheumatoid arthritis (RA), focused on the balance between T helper type 17 cells and regulatory T cells (Tregs). In humans, both subpopulations depend on ...
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(Universidad de ChileCyberDocs, 2009)NKG2D (Natural Killer Group 2, type D) es un receptor de activación de las células Natural Killer de sangre periférica (NK), uterinas (uNK) y TCD8+ humanos. Son ligandos de NKG2D (NKG2DL), las proteínas relacionadas ...
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(Frontiers Media, 2015)The ability of dendritic cells (DCs) to initiate and modulate antigen-specific immune responses has made them attractive targets for immunotherapy. Since DC research in humans is limited by the scarcity of DC populations ...
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(Universidad de Chile, 2008)La artritis reumatoide (AR) es una enfermedad sistémica autoinmune que se caracteriza por la inflamación crónica y progresiva de las articulaciones sinoviales llevando a la destrucción del cartílago y hueso articular. En ...
