Browsing by Author "201-0535197"
Now showing items 1-20 of 21
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Donoso, M. V.; Carvajal, A.; Paredes Vargas, Alfonso; Tomic, A.; Koenig, Cecilia S.; Huidobro Toro, Juan Pablo (ELSEVIER SCIENCE INC, 2002-09)Neuropeptide Y (NPY) and noradrenaline (NA) are co-transmitters at many sympathetic synapses, but it is not yet clear if their release is independently regulated. To address this question, we quantified the electrically ...
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Jofré Romeo, Fabián J. (Universidad de ChileCyberDocs, 2010)El componente nervioso simpático regula la función ovárica y su actividad nerviosa aumenta al final del periodo reproductivo, lo que supone una relación entre envejecimiento ovárico y aumento del tono simpático. Este ...
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Bloqueo farmacológico de los receptores [beta]-adrenérgicos en ratas en el periodo de subfertilidad Fernandois Vicencio, Daniela del Pilar (Universidad de ChileCyberDocs, 2011)En la actualidad la mujer ha decido posponer la maternidad hasta después de los 30 años. El aplazar la maternidad hacia la ventana de subfertilidad (31 a 41 años), provoca una disminución de la fertilidad y en el éxito ...
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Heras, Violeta; Castellano, Juan Manuel; Fernandois, Daniela; Velasco, Inmaculada; Rodríguez Vázquez, Elvira; Roa, Juan; Vázquez, María Jesús; Ruiz Pino, Francisco; Rubio, Matías; Pineda, Rafael; Torres, Encarnación; Avendaño, María Soledad; Paredes Vargas, Alfonso; Pinilla, Leonor; Belsham, Denise; Dieguez, Carlos; Gaytan, Francisco; Casals, Nuria; López, Miguel; Tena Sempere, Manuel (Cell, 2020)Childhood obesity, especially in girls, is frequently bound to earlier puberty, which is linked to higher disease burden later in life. The mechanisms underlying this association remain elusive. Here we show that brain ...
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Bilger, Marie; Heger, Sabine; Brann, Darrell W.; Paredes Vargas, Alfonso; Ojeda, Sergio R. (ENDOCRINE SOC, 2001-05)Gamma amino butyric acid (GABA) is the main inhibitory neuro-transmitter controlling LH-releasing hormone (LHRH) secretion in the mammalian hypothalamus. Whether alterations in GABA homeostasis within discrete regions of ...
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Acuña Rodríguez, Eric M. (Universidad de ChileCyberDocs, 2008)El cese de la función ovárica está dado principalmente por la pérdida del número de folículos primordiales. Durante el envejecimiento, existe un decrecimiento en el número de folículos ováricos. En mujeres se ha establecido ...
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Gálvez, A.; Paredes Vargas, Alfonso; Fiedler Temer, Jenny; Venegas Santos, Mauricio; Lara Peñaloza, Hernán (HUMANA PRESS INC, 1999-04)A 3-wk period of stress promotes the development of ovarian cysts in rats apparently mediated by increased sympathetic nerve activity and ovarian steroid secretion. After 11 wk of stress, these parameters are indistinguishable ...
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Garrido Palma, Maritza; Fernandois, Daniela; Venegas Santos, Mauricio; Paredes Vargas, Alfonso (Bioscientifica Ltd., 2018)Recently, the influence of adrenergic activity over ovarian function, and thus fertility, has begun to gain importance. Previous studies have shown that adrenergic activity through norepinephrine (NE) participates in the ...
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Díaz Montecinos, Ariel Eduardo (Universidad de ChileCyberDocs, 2009)Debido a la demanda social, la mujer ha tenido que postergar la maternidad. Esto presenta el inconveniente de que con el aumento de la edad decrece el número y la calidad de los folículos, disminuyendo progresivamente la ...
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Lara Peñaloza, Hernán; Dissen, G. A.; Leyton Canales, Víctor; Paredes Vargas, Alfonso; Fuenzalida Cruz, Héctor; Fiedler Temer, Jenny; Ojeda, Sergio R. (ENDOCRINE SOC, 2000-03)A form of polycystic ovary (PCO) resembling some aspects of the human PCO syndrome can be induced in rats by a single injection of estradiol valerate (EV). An increase in sympathetic outflow to the ovary precedes, by several ...
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Dissen, G. A.; Lara Peñaloza, Hernán; Leyton Canales, Víctor; Paredes Vargas, Alfonso; Hill, D. F.; Costa, M. E.; Martínez Serrano, A.; Ojeda, Sergio R. (ENDOCRINE SOC, 2000-03)A single injection of estradiol valerate induces a form of cystic ovary resembling some aspects of the human polycystic ovarian syndrome. Preceding the development of follicular cysts, there is an increase in intraovarian ...
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Fernandois, D.; Na, E.; Cuevas, F.; Cruz, G.; Lara Peñaloza, Hernán; Paredes Vargas, Alfonso (Bioscientifica, 2016)We have previously reported that kisspeptin (KP) may be under the control of the sympathetic innervation of the ovary. Considering that the sympathetic activity of the ovary increases with aging, it is possible that ...
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Barra, Rafael; Cruz Neculpán, Gonzalo Andrés; Mayerhofer, Artur; Paredes Vargas, Alfonso; Lara Peñaloza, Hernán (Society for Reproduction and Fertility, 2014)Chronic cold stress applied to adult rats activates ovarian sympathetic innervation and develops polycystic ovary (PCO) phenotype. The PCO syndrome in humans originates during early development and is expressed before or ...
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Romero Osses, Carmen; Paredes Vargas, Alfonso; Dissen, G. A.; Ojeda, Sergio R. (ENDOCRINE SOC, 2002-04)The neurotrophin nerve growth factor (NGF) and its two membrane-anchored receptors are expressed in the developing ovary before the organization of the first primordial follicles. In the absence of NGF, the growth of ...
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Amweg, A. N.; Salvetti, N. R.; Stangaferro, M. L.; Paredes Vargas, Alfonso; Lara, H. H.; Rodríguez, F. M.; Ortega, H. H. (Elsevier, 2013)Cystic ovarian disease (COD) is an important cause of infertility in cattle, and ACTH has been involved in regulatory mechanisms related to ovarian function associated with ovulation, steroidogenesis, and luteal function. ...
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Ricu Moya, Manuel Alejandro (Universidad de Chile, 2013-01)Kisspeptina es un péptido de 145 aa. el cual juega un rol clave en la secreción de GnRH, participando en conjunto con las catecolaminas en la regulación de la ovulación a nivel hipotalámico. La mayoría de las neuronas ...
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Peripheral and Central Mechanisms Involved in the Hormonal Control of Male and Female Reproduction Rudolph, L. M.; Bentley, G.; Calandra, R.; Paredes Vargas, Alfonso; Tesone, M.; Wu, T. J.; Micevych, P. E. (Wiley, 2016)Reproduction involves the integration of hormonal signals acting across multiple systems to generate a synchronised physiological output. A critical component of reproduction is the luteinising hormone (LH) surge, which ...
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Rise in endothelium-derived NO after stimulation of rat perivascular sympathetic mesenteric nerves Boric, M. P.; Figueroa, X. F.; Donoso, M. V.; Paredes Vargas, Alfonso; Poblete, I.; Huidobro Toro, Juan Pablo (AMER PHYSIOLOGICAL SOC, 1999-09)To evaluate whether sympathetic activity induces nitric oxide (NO) production, we perfused the rat arterial mesenteric bed and measured luminally accessible norepinephrine (NE), NO, and cGMP before, during, and after ...
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Lacassie, Yves; Johnson, Britt; Lay-Son, Guillermo; Quintana, Rita; King, Andrew; Cortés, Fanny; Álvarez, Cecilia; Gómez, Ricardo; Vargas, Alfonso; Chalew, Stuart; King, Alejandra; Guardia, Sylvia; Sorensen, Ricardo U.; Aradhya, Swaroop (Wiley, 2020)Autosomal recessive SOPH syndrome was first described in the Yakuts population of Asia by Maksimova et al. in 2010. It arises from biallelic pathogenic variants in the NBAS gene and is characterized by severe postnatal ...
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Romero Osses, Carmen; Dissen, G. A.; DeChiara, T. M.; Reichardt, L.; Cornea, A.; Ojeda, Sergio R.; Paredes Vargas, Alfonso; Xu, B. J. (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004-03-15)Although it is well established that both follicular assembly and the initiation of follicle growth in the mammalian ovary occur independently of pituitary hormone support, the factors controlling these processes remain ...