Now showing items 1-18 of 18

    • Vial, Clarisa; Armas Portela, Rosario; Avila, Jesús; González, Mauricio; Maccioni Baraona, Ricardo (Kluwer Academic Publishers, 1995)
      Microtubule-associated proteins (MAPs) interact with tubulin in vitro and in vivo. Despite that there is a large amount of information on the roles of these proteins in neurons, the data on non-neuronal MAPs or MAPs-related ...
    • Ruiz, Lina María; Jensen, Erik L.; Bustos, Rodrigo I.; Argüelloa, Graciela; Gutierrez-Garcia, Ricardo; González, Mauricio; Hernández, Claudia; Paredes, Rodolfo; Simon, Felipe; Riedel, Claudia; Ferrick, David; Elorza, Alvaro A. (Wiley-Liss Inc., 2014)
      Copper is an essential cofactor of complex IV of the electron transfer chain, and it is directly involved in the generation of mitochondrial membrane potential. Its deficiency induces the formation of ROS, large mitochondria ...
    • Araya, Magdalena; Núñez, Héctor; Pavez, Leonardo; Arredondo, Miguel; Méndez, Marco; Cisternas, Felipe; Pizarro Aguirre, Fernando; Sierralta, Walter; Uauy Dagach-Imbarack, Ricardo; González, Mauricio (2012)
      Liver cells respond to copper loading upregulating protective mechanisms. However, to date, except for liver content, there are no good indicators that identify individuals with excess liver copper. We hypothesized that ...
    • Vázquez, Mary C.; del Pozo, Talía; Robledo, Fermín; Carrasco, Gonzalo; Pavez, Leonardo; Olivares, Felipe; González, Mauricio; Zanlungo, Silvana (2011)
      Background: Niemann-Pick type C disease (NPC) is a neurovisceral lipid storage disorder mainly characterized by unesterified cholesterol accumulation in lysosomal/late endosomal compartments, although there is also an ...
    • Fernández Gómez, Beatriz; Maldonado, Jonathan; Mandakovic, Dinka; Gaete, Alexis; Gutiérrez, Rodrigo A.; Maass Sepúlveda, Alejandro; Cambiazo, Veronica; González, Mauricio (Nature Publishing Group, 2019)
      The rhizosphere is considered the primary place for soil microbiome differentiation and plays a key role in plant survival, especially for those subjected to environmental stress. Using high-throughput sequencing of the ...
    • Arrázola, Macarena S.; Varela Nallar, Lorena; Colombres, Marcela; Toledo, Enrique M.; Cruzat, Fernando; Pavez, Leonardo; Assar, Rodrigo; Aravena, Andrés; González, Mauricio; Montecino, Martín; Maass Sepúlveda, Alejandro; Martínez Aguilera, Servet; Inestrosa, Nibaldo C. (2009)
      Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory ...
    • Latorre, Mauricio; Burkhead, Jason L.; Hodar, Christian; Arredondo, Miguel; González, Mauricio; Araya, Magdalena (Elsevier GmbH, 2019)
      The independent toxic effects of copper and acetaminophen are among the most studied topics in liver toxicity. Here, in an animal model of Cebus capucinus chronically exposed to high dietary copper, we assessed clinical ...
    • Del Pozo, Talía; Miranda, Simón; Latorre, Mauricio; Olivares, Felipe; Pavez, Leonardo; Gutiérrez, Ricardo; Maldonado, Jonathan; Hinrichsen, Patricio; Defilippi, Bruno G.; Orellana, Ariel; González, Mauricio (American Chemical Society, 2019)
      Cold storage of fruit is one of the methods most commonly employed to extend the postharvest lifespan of peaches (Prunus persica (L.) Batsch). However, fruit quality in this species is affected negatively by mealiness, a ...
    • Cambiazo Ayala, Verónica; González, Mauricio; Maccioni Baraona, Ricardo (1995)
      Abstract: Microtubule‐associated proteins (MAPs) play major regulatory roles in the organization and integrity of the cytoskeletal network. Our main interest in this study was the identification and the analysis of structural ...
    • Zúñiga, Alejandro; Hödar Quiroga, Christian; Hanna, Patricia; Ibáñez, Freddy; Moreno, Pablo; Pulgar Tejo, Rodrigo; Pastenes, Luis; González, Mauricio; Cambiazo Ayala, Verónica (2009)
      Background: Morphogenetic events that shape the Drosophila melanogaster embryo are tightly controlled by a genetic program in which specific sets of genes are up-regulated. We used a suppressive subtractive hybridization ...
    • Mandakovic, Dinka; Glasner, Benjamín; Maldonado, Jonathan; Aravena, Pamela; González, Mauricio; Cambiazo Ayala, Verónica; Pulgar Tejo, Rodrigo (Frontiers Media, 2016)
      The gram negative facultative bacterium P. salmonis is the etiological agent of Salmonid Rickettsial Septicaemia (SRS), a severe disease that causes important economic losses in the global salmon farmer industry. Despite ...
    • González, Mauricio; Tapia, Lucía; Alvarado, Milton; Tornero, Jesús D.; Fernández, Ramón (Royal Soc of Chemistry, 1999)
      TXRF (total reflection X-ray fluorescence spectrometry), a rapid and reliable multi-element method, was applied to quantify intracellular concentrations of trace and non-trace elements in different mammalian cell lines. ...
    • Miranda, Simón; Vilches, Paulina; Suazo, Miriam; Pavez, Leonardo; García, Katherine; Méndez, Marco; González, Mauricio; Meisel, Lee; Defilippi, Bruno G.; Pozo, Talia del (Elsevier, 2020)
      Sweet cherry is a valuable non-climacteric fruit with elevated phytonutrients, whose fruit quality attributes are prone to rapid deterioration after harvest, especially peel damage and water loss of stem. Here the metabolic ...
    • Vásquez Dean, Javiera; Maza, Felipe; Morel, Isidora; Pulgar Tejo, Rodrigo; González, Mauricio (Soc Biolgia Chile, 2020)
      Arid environments are defined by the lack of water availability, which is directly related to the mean annual precipitation (MAP), and high values of solar irradiation, which impacts the community composition of animals, ...
    • Mandakovic, Dinka; Maldonado, Jonathan; Pulgar Tejo, Rodrigo; Cabrera, Pablo; Gaete, Alexis; Urtuvia, Viviana; Seeger, Michael; Cambiazo Ayala, Verónica; González, Mauricio (Springer Tokyo, 2018)
      © 2018, Springer Japan KK, part of Springer Nature.As a consequence of the severe climatic change affecting our entire world, many lakes in the Andes Cordillera are likely to disappear within a few decades. One of these ...
    • Domínguez, Calixto; Zúñiga, Alejandro; Hanna, Patricia; Hödar Quiroga, Christian; González, Mauricio; Cambiazo Ayala, Verónica (Elsevier Science BV., 2016)
      In the early Drosophilamelanogaster embryo, the gene regulatory network controlled by Dpp signaling is involved in the subdivision of dorsal ectoderm into the presumptive dorsal epidermis and amnioserosa. In this work, ...
    • Quesille-Villalobos, Ana María; Parra, Angel; Maza, Felipe; Navarrete, Paola; González, Mauricio; Latorre, Mauricio; Toro, Magaly; Reyes-Jara, Angélica (Frontiers Media S.A., 2019)
      Listeria monocytogenes is a foodborne pathogen that can cause severe disease in susceptible humans. This microorganism has the ability to adapt to hostile environmental conditions such as the low temperatures used by the ...
    • Cambiazo Ayala, Verónica; González, Mauricio; Isamit, Cristián; Maccioni Baraona, Ricardo (1999)
      Through major research advances in the study of cytoskeletal organization, an integrated view of the complexity of this system has emerged. Recent findings on the microtubule-interacting protein Mip-90, which associates ...