Browsing by Author "2520111a-0682-4502-af4b-80205eb4155c"
Now showing items 1-20 of 28
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Reyna G, Sixto; Valenzuela Báez, Rodrigo; Villanueva, María Elena (Sociedad Chilena de Bromatología y Toxicología, 2018)Epidemiological and clinical studies have reported multiple benefits from the intake of Long Chain Polyunsaturated Fatty Acids n-3 (LC-PUFA n-3), EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid); however, ...
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Valenzuela Báez, Rodrigo; Espinosa Escalona, Alejandra; Llanos Vidal, Paola; Hernández Rodas, María Catalina; Barrera Ramírez, Cynthia; Vergara, Daniela; Romero Palacios, Nalda; Pérez, Francisco; Ruz Ortiz, Manuel; Videla Cabrera, Luis (Royal Soc Chemistry, 2016)Non-alcoholic fatty liver disease (NAFLD) is characterized by liver steatosis, oxidative stress, and drastic depletion of n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA), namely, eicosapentaenoic acid (C20:5 n-3, ...
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Rincón Cervera, Miguel Ángel; Villarreal Rubio, María Beatriz; Valenzuela Báez, Rodrigo; Valenzuela Bonomo, Carlos (Wiley, 2017)Fish by-products may become alternative sources of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). However, due to the high enzymatic activity in these biological tissues, special care must be taken to prevent ...
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Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (Elsevier, 2018-06)Normal liver function includes a number of metabolic processes, secretion of cellular mediators and its role in immunobiology; these require a high energy supply, which is further enhanced under adverse conditions triggering ...
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Chamorro Melo, Rodrigo; González, María F.; Aliaga Godoy, Rocío; Gengler Prieto, Valentina; Balladares, Constanza; Barrera Ramírez, Cynthia; Bascuñán Gamboa, Karla; Bazinet, Richard P.; Valenzuela Báez, Rodrigo (Wiley, 2020)There has been increasing interest in vegan diets, but how this dietary pattern regulates tissue fatty acids (FA), especially in men, is unclear. Our aim was to evaluate the effect of a vegan diet on plasma, erythrocyte, ...
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Echeverría González, Francisca; Valenzuela Báez, Rodrigo; Hernández Rodas, María Catalina; Valenzuela Bonomo, Carlos (Elsevier, 2017)Docosahexaenoic acid (C22: 6n-3, DHA) is a long-chain polyunsaturated fatty acid of marine origin fundamental for the formation and function of the nervous system, particularly the brain and the retina of humans. It has ...
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Orellana, Paula; Valenzuela Bonomo, Carlos; Morales, Gladys; Valenzuela Báez, Rodrigo (Sociedad Chilena de Nutrición, 2018)El estudio focalizado en dilucidar el rol neuroprotector del ARA y del DHA a lo largo del ciclo vital ha cobrado cada vez más interés puesto que se continúan descubriendo mecanismos mediante los cuales estos ácidos ...
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Castaño Moreno, Erika; Castillo, Valeska; Peñailillo, Reyna; Llanos Silva, Miguel; Valenzuela Báez, Rodrigo; Ronco Macchiavello, Ana (Elsevier, 2020)Micronutrients (folates and vitamin B12) and long chain polyunsaturated fatty acids (LC-PUFAs) are linked through the one carbon cycle. We studied the effects of pre and postnatal high FA/low B12 diets (HFLB12) on hepatic ...
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Hernández, María Catalina; Rojas Moncada, Pamela; Carrasco Naranjo, Fernando; Basfi-fer Obregón, Karen; Valenzuela Báez, Rodrigo; Codoceo, Juana; Inostroza Escobar, Jorge; Ruz Ortiz, Manuel (Elsevier, 2020)Background/Objective: Membrane flexibility can be a determining factor in pathophysiological mechanisms of type 2 diabetes (T2D). As a cofactor of delta-5 desaturase (D5D) and delta-6 desaturase (D6D), and gene expression ...
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Rincón Cervera, Miguel Ángel; Galleguillos Fernández, Raúl; González Barriga, Barriga; Valenzuela Báez, Rodrigo; Speisky Cosoy, Hernán; Fuentes, Jocelyn; Valenzuela, Alfonso (Wiley, 2020)
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Echeverría González, Francisca; Ortíz, Macarena; Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (MDPI AG, 2017)Hydroxytyrosol (HT) ((3,4-Dihydroxyphenyl) ethanol) is a polyphenol mainly present in extra virgin olive oil (EVOO) but also in red wine. It has a potent antioxidant effect related to hydrogen donation, and the ability to ...
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Valenzuela Báez, Rodrigo; Echeverría González, Francisca; Ortíz, Macarena; Rincón Cervera, Miguel Ángel; Espinosa Escalona, Berta; Hernández Rodas, María Catalina; Illesca, Paola; Valenzuela Bonomo, Carlos; Videla Cabrera, Luis (Biomed Central Ltd., 2017)Background: Eicosapentaenoic acid (EPA, C20:5n-3), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (AA, C20:4n-6) are long-chain polyunsaturated fatty acids (LCPUFAs) with relevant roles in the organism. EPA and ...
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Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (MDPI, 2020)Nonalcoholic fatty liver disease (NAFLD) is present in approximately 25% of the population worldwide. It is characterized by the accumulation of triacylglycerol in the liver, which can progress to steatohepatitis with ...
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Barrera Ramírez, Cynthia; Valenzuela Báez, Rodrigo; Rincón Cervera, Miguel Ángel; Espinosa, Alejandra; López Arana, Sandra; González Mañan, Daniel; Romero Palacios, Nalda; Vargas, Romina; Videla Cabrera, Luis (Elsevier, 2020)The administration of iron induces liver oxidative stress and depletion of long-chain polyunsaturated fatty acids (LCPUFAs), n-6/n-3 LCPUFA ratio enhancement and fat accumulation, which may be prevented by antioxidant-rich ...
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Carrasco Navarro, Gabriela; Valenzuela Báez, Rodrigo (Consorcio Lechero, 2020)El cáncer es un complejo proceso celular que implica múltiples y diversas alteraciones a nivel molecular, las cuales tienen como característica principal la pérdida en el control de la reproducción celular. Se considera ...
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Soto Alarcón, Sandra A.; Valenzuela Báez, Rodrigo; Valenzuela Bonomo, Carlos; Videla Cabrera, Luis (Bentham Science Publ LTD, 2018)Background and Objective: The liver is an organ susceptible to a multitude of injuries that causes liver damage, like steatosis, non-alcoholic steatohepatitis, cirrhosis, hepatocellular carcinoma, and ischemia-reperfusion ...
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Echeverría González, Francisca; Ortiz, Macarena; Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (Elsevier, 2016)Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that function as ligand-dependent transcription factors that can be activated by different types of fatty acids (FAs). Three isoforms of PPARs have ...
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Valenzuela Báez, Rodrigo; Bascuñán Gamboa, Karla; Chamorro Melo, Rodrigo; Barrera Ramírez, Cynthia; Sandoval Zamorano, Jorge; Puigrredón, Claudia; Parraguez, Gloria; Orellana, Paula; González, Valeria; Valenzuela Bonomo, Carlos (MDPI AG, 2015)alpha-Linolenic acid (ALA) is the precursor of docosahexaenoic acid (DHA) in humans, which is fundamental for brain and visual function. Western diet provides low ALA and DHA, which is reflected in low DHA in maternal milk. ...
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Ortiz, Macarena; Echeverría González, Francisca; Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (2019-03)
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Valenzuela Bonomo, Carlos; Rincón Cervera, Miguel Ángel; Valenzuela Báez, Rodrigo (Sociedad Chilena de Nutrición, 2016)The relationship of cholesterol to atherogenesis already fulfilled one hundred years. The merit of this important discovery is attributed to a Russian military doctor, Nikolai Anichkov, who using rabbits as experimental ...