Browsing by Author "2882fd7a-b480-41c1-bddc-4d213131c50e"
Now showing items 1-12 of 12
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Muñoz, Aira; Lavandero González, Sergio; Donoso, Eduardo; Puente Piccardo, Javier; Sapag Hagar, Mario (1985)The effect on lactose production of several external modulators of intracellular cyclic AMP was studied in rat mammary gland tissue slices and explants. Adrenaline, a β-adrenergic receptor effector, forskolin, a direct ...
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Alberti, Carolina; Gonzalez, Juan; Maldonado, Horacio; Medina, Fernando; Barriga, Andrés; García Nannig, Lorena; Kettlun, Ana; Collados, Lucía; Puente, Javier; Cartier Rovirosa, Luis; Valenzuela, Maria (2009)HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive CNS disease leading to corticospinal tract degeneration. Various degenerative diseases have increased neurofilament subunit concentration ...
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Puente, Javier; Maturana, Patricio; Miranda, Dante; Navarro, Carlos; Wolf, Marion E.; Mosnaim, Aron D. (1992)We studied the effect of methionine-enkephalin (MET) and β-endorphin upon human peripheral blood lymphocyte natural killer cell (NKC) activity in a group of healthy volunteers (n = 27; 17 male and 10 female, age ± SD and ...
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Mosnaim, Aron D.; Puente, Javier; Saavedra, Rolando; Diamond, Seymour; Wolf, Marion E. (2003)A number of drugs with the phenothiazine molecule in their chemical structure inhibit in a dose-dependent manner human plasmatic aminopeptidase leucine5-enkephalin (LEU) metabolism. Half-life peptide degradation was ...
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Maldonado, Horacio; Ramírez, Eugenio; Utreras Puratich, Elías; Pando, María E.; Kettlun, Ana M.; Chiong Lay, Mario; Kulkarni, Ashok B.; Collados, Lucía; Puente, Javier; Cartier Rovirosa, Luis; Valenzuela, María A. (2011)Human T-cell leukemia virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neurodegenerative disease characterized by selective loss of axons and myelin in the corticospinal tracts. This ...
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Navarrete, Mariely; García, Jocelyn; Dutzan, Nicolás; Henríquez, Leslie; Puente, Javier; Carvajal, Paola; Hernandez, Marcela; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2014)Macrophages account for 5% to 30% of the inflammatory infiltrate in periodontitis and are activated by the classic and alternative pathways. These pathways are identified by indirect markers, among which interferon (IFN)-γ ...
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Vernal Astudillo, Rolando; Chaparro, Alejandra; Graumann, Rebecca; Puente, Javier; Valenzuela, Maria Antonieta; Gamonal Aravena, Jorge Antonio (2004)Background: Receptor activator of nuclear factor κB ligand (RANK-L) is a cytokine involved in the regulation of osteoclastogenesis in bone remodeling and inflammatory osteolysis. One of the major causes of tooth loss in ...
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Alberti, Carolina; Cartier Rovirosa, Luis; Valenzuela, María A.; Puente, Javier; Tanaka, Yuetsu; Ramirez, Eugenio (2011)There is no effective therapy for human T-cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Glucocorticoids are effective to reduce the motor disability in these patients, ...
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Maturana, Patricio; Puente, Javier; Miranda, Dante; Sepulveda, Cecilia; Wolf, Marion E.; Mosnaim, Aron D. (1991)Natural killer cell activity (NKCA) was studied in a group of patients (n = 11) with septic shock. When compared with controls (n = 10), these individuals showed a statistically significant reduction in NKCA at each of the ...
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Puente, Javier; Miranda, Dante; Blanco, Luz; Wolf, Marion E.; Mosnaim, Aron D. (1998)The increase in human natural killer cell activity (NKCA) in samples of peripheral blood mononuclear cells (PBMC) elicited by their incubation with bacterial lipopolysaccharide (LPS), appears to result from an indirect ...
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Mosnaim, Aron D.; Ranade, Vasant V.; Wolf, Marion E.; Puente, Javier; Antonieta Valenzuela, M. (2006)The chemical structure of phenothiazine provides a most valuable molecular template for the development of agents able to interact with a wide variety of biological processes. Synthetic phenothiazines (with aliphatic, ...
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Medina, Fernando; Quintremil, Sebastian; Alberti, Carolina; Barriga, Andres; Cartier Rovirosa, Luis; Puente, Javier; Ramírez, Eugenio; Ferreira, Arturo; Tanaka, Yuetsu; Valenzuela, Maria Antonieta (Mary Ann Liebert Inc., 2014)The human retrovirus human T cell lymphotropic virus type-I (HTLV-1) is the etiologic agent of HTLV-1-Associated myelopathy/tropical spastic paraparesis (HAM/TSP). Axonal degeneration in HAM/TSP patients occurs without ...