Browsing by Author "4f41c161-af51-4028-85d1-ae02e3188a0c"

Now showing items 1-5 of 5

    • Cellular and molecular mechanisms regulating neuronal growth by brain-derived neurotrophic factor 
      González, Andrés; Moya Alvarado, Guillermo; González Billault, Christian; Bronfman, Francisca (Wiley, 2016)
      Brain-derived neurotrophic factor (BDNF) and its receptors TrkB and p75 regulate dendritic and axonal growth during development and maintenance of the mature nervous system; however, the cellular and molecular mechanisms ...
    • Cholinergic abnormalities, endosomal alterations and up-regulation of nerve growth factor signaling in ... 
      Cabeza, Carolina; Figueroa, Alicia; Lazo, Oscar M.; Galleguillos, Carolina; Pissani, Claudia; Klein, Andrés; González Billault, Christian; Inestrosa, Nibaldo C.; Alvarez, Alejandra R.; Zanlungo, Silvana; Bronfman, Francisca (2012)
      Background: Neurotrophins and their receptors regulate several aspects of the developing and mature nervous system, including neuronal morphology and survival. Neurotrophin receptors are active in signaling endosomes, which ...
    • Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production 
      Langjahr, Patricia; Díaz Jiménez, David; De La Fuente, Marjorie; Rubio, Estefhany; Golenbock, Douglas; Bronfman, Francisca; Quera, Rodrigo; Lez, María Julieta Gonzá; Hermoso, Marcela A.; Benjamim, Claudia Farias (Public Library of Science, 2014)
      © 2014 Langjahr et al.Toll-like receptor (TLR) 2, a type I membrane receptor that plays a key role in innate immunity, recognizes conserved molecules in pathogens, and triggering an inflammatory response. It has been ...
    • Rab GTPase signaling in neurite outgrowth and axon specification 
      Villarroel Campos, David Leonardo; Bronfman, Francisca; González Billault, Christian (John Wiley and Sons Inc., 2016)
      © 2016 Wiley Periodicals, Inc. Neurons are highly polarized cells that contain specialized subcellular domains involved in information transmission in the nervous system. Specifically, the somatodendritic compartment ...
    • Rab35 functions in axon elongation are regulated by P53-related protein kinase in a mechanism that involves ... 
      Villarroel Campos, David Leonardo; Henríquez, Daniel R.; Bodaleo, Felipe J.; Oguchi, Mai E.; Bronfman, Francisca; Fukuda, Mitsunori; González Billault, Christian (Society for Neuroscience, 2016)
      © 2016 the authors. Rab35 is a key protein for cargo loading in the recycling endosome. In neuronal immortalized cells, Rab35 promotes neurite differentiation. Here we describe that Rab35 favors axon elongation in rat ...