Browsing by Author "8a7914fb-4ac9-4d33-a2a7-a018fa0fa216"

Now showing items 1-6 of 6

    • A synthetic peptide homologous to functional domain of human IL-10 down-regulates expression of MHC class ... 
      Kurte, Mónica; López, Mercedes; Aguirre, Adam; Escobar, Alejandro; Aguillón Gutiérrez, Juan Carlos; Charo, Jehad; Larsen, Christian G.; Kiessling, Rolf; Salazar Onfray, Flavio (American Association of Immunologists, 2004)
      Tumor cells treated with IL-10 were shown to have decreased, but peptide-inducible expression of MHC class I, decreased sensitivity to MHC class I-restricted CTL, and increased NK sensitivity. These findings could be ...
    • Immunoglobulins concentration and B cell counts as severity markers in adult community-acquired pneumonia ... 
      Luchsinger, Vivian; Lizama, Luis; Garmendia, María Luisa; Tempio, Fabián; Ruiz, Mauricio; Pizarro, Rolando; Rossi, Patricio; Huenchur, Lucía; Moreno, Cristian; López, Mercedes; Ampuero, Sandra; Larrañaga, Carmen; Avendaño, Luis Fidel (Lippincott Williams & Wilkins, 2020)
      Community-acquired pneumonia (CAP) is a worldwide cause of morbidity and mortality. Immunoglobulins (Igs) and B cells quantification studies in CAP are few and show discrepancies. Serum IgA acts as a powerful natural ...
    • Melanocytes and melanin represent a first line of innate immunity against Candida albicans 
      Tapia, Cecilia; Falconer, Maryanne; Tempio, Fabián; Falcón, Felipe; López, Mercedes; Fuentes, Marisol; Alburquenque, Claudio; Amaro, José; Bucarey, Sergio A.; Nardo, Anna Di (Oxford University Press, 2014)
      Melanocytes are dendritic cells located in the skin and mucosae that synthesize melanin. Some infections induce hypo-or hyperpigmentation, which is associated with the activation of Toll-like receptors (TLRs), especially ...
    • Molecular signatures associated with tumor-specific immune response in melanoma patients treated with ... 
      García-Salum, Tamara; Villablanca, Andrea; Matthäus, Franziska; Tittarelli, Andrés; Baeza, Mauricio; Pereda, Cristián; Gleisner Muñoz, María Alejandra; González, Fermín; López, Mercedes; Hoheisel, Jörg; Norgauer, Johannes; Gebicke Haerter, Peter; Salazar Onfray, Flavio (Impact Journals LLC, 2018)
      Purpose: We previously showed that autologous dendritic cells (DCs) loaded with an allogeneic heat shock (HS)-conditioned melanoma cell-derived lysate, called TRIMEL, induce T-cell-mediated immune responses in stage IV ...
    • Targeting innate immune cells for immunotherapy 
      Carreño, Leandro J.; Prados Rosales, Rafael; López, Mercedes; Baena, Andrés; González, Pablo A. (Hindawi Limited, 2017)
    • The role of regulatory T lymphocytes in the induced immune response mediated by biological vaccines 
      López, Mercedes; Aguilera, Raquel; Pérez Núñez, Claudio; Mendoza Naranjo, Ariadna; Pereda, Cristian; Ramirez, Marcos; Ferrada, Carlos; Aguillón Gutiérrez, Juan Carlos; Salazar Onfray, Flavio (Elsevier GmbH, 2006)
      Immunotherapy has become a novel therapeutic alternative for various kinds of tumours. Recently, we have finalized the first phase I clinical study in Chile for the treatment of advanced malignant melanoma, using dendritic ...