Now showing items 1-13 of 13

    • Santolaya de Pablo, María Elena; Alvarez, Ana M.; Avilés, Carmen L.; Becker, Ana; Mosso, Claudio; O'Ryan Gallardo, Miguel; Payá, Ernesto; Salgado, Carmen; Silva, Pamela; Topelberg, Santiago; Tordecilla, Juan; Varas, Mónica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marcela (2007)
      BACKGROUND: Early identification of children with cancer at risk for death during a febrile neutropenic (FN) episode may increase their possibility for survival. Our aim was to identify at the time of admission, clinical ...
    • Cortez, Daniela; Rodríguez, Natalie; Benadof, Dona; Zamorano, Agustín; Tordecilla, Juan (2012)
      The use of intensive chemotherapy has improved survival of children with cancer. However, this is associated to severe and maintained neutropenia, increasing risks of severe infections like bacteremia. Aim: To update ...
    • Ducasse, Karen; Fernández, José P.; Salgado, Carmen; Álvarez, Ana M.; Avilés, Carmen L.; Becker, Ana; Topelberg, Santiago; Tordecilla, Juan; Varas, Mónica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marcela; Santolaya de Pablo, María Elena (Sociedad Chilena de Infectologia, 2014)
      Introduction: Leukemia is the most common cancer in Chilean children. Acute lymphoblastic leukemia (ALL) is more prevalent and longer survival compared to acute myeloid leukemia (AML). Aims: To describe episodes of febrile ...
    • Santolaya de Pablo, María Elena; Farfán, Mauricio J.; Maza León, Verónica de la; Cociña, Manuela; Santelices, Felipe; Alvarez, Ana M.; Avilés, Carmen L.; Becker, Ana; O'Ryan Gallardo, Miguel; Román, Paulina; Salgado, Carmen; Silva, Pamela; Topelberg, Santiago; Tordecilla, Juan; Varas, Mónica; Vi (Lippincott Williams and Wilkins, 2011)
      Background: Bacterial isolation using conventional microbiologic techniques rarely surpasses 25% in children with clinical and laboratory findings indicative of an invasive bacterial infection. The aim of this study was ...
    • Torres, Juan P.; Labraña, Yenis; Ibañez, Carolina; Kasaneva, Pilar; Farfán, Mauricio J.; Maza León, Verónica de la; Villarroel, Milena; Vergara, Ivonne; Piemonte, Paula; Zubieta, Marcela; Salgado, Carmen; Tordecilla, Juan; Topelberg, Santiago; O'Ryan Gallardo, Miguel; Santolaya de Pablo, María Elena (Lippincott Williams and Wilkins, 2012)
      Background: The role of respiratory viral infections (RVIs) as a cause of overall fever and neutropenia (FN) episodes in children with cancer has been less characterized than bacterial infections. We conducted a study aimed ...
    • Joannon, Pilar; Oviedo, Iris; Campbell, Myriam; Tordecilla, Juan (2004)
      Background. The objectives of this study were: (1) to analyze the relation of serum methotrexate (MTX) concentration with creatinine clearance, (2) to compare the leucovorin rescue dose administered to the patients based ...
    • Lucero, Yalda; Brücher, Roberto; Alvarez, Ana María; Becker, Ana; Cofré, José; Enríquez, Nancy; Payá, Ernesto; Salgado, Carmen; Santolaya de Pablo, María Elena; Tordecilla, Juan; Varas, Mónica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marcela; O'Ryan Gallardo, Miguel (2002)
      BACKGROUND: Invasive fungal infections (IFI) cause prolonged hospitalizations and increase the possibility of death among patients with cancer and febrile neutropenia (FN). Up to 10% of febrile neutropenic episodes may be ...
    • Maldonado, M. Eliana; Acuña, Mirta; Álvarez, Ana M.; Avilés, Carmen L.; Maza León, Verónica de la; Salgado, Carmen; Tordecilla, Juan; Varas, Mònica; Venegas, Marcela; Villarroel, Milena; Zubieta, Marcela; Santolaya de Pablo, María Elena (Sociedad Chilena de Infectologia, 2018)
      © 2018, Sociedad Chilena de Infectologia. All rights reserved. Background: Microorganisms isolated from blood cultures (BC) in patients with febrile neutropenia (NF) vary over time, requiring systematic monitoring to guide ...
    • Santolaya de Pablo, María Elena; Alvarez, Ana M.; Aviles, Carmen L.; Becker, Ana; King, Alejandra; Mosso, Claudio; O'Ryan Gallardo, Miguel; Paya, Ernesto; Salgado, Carmen; Silva, Pamela; Topelberg, Santiago; Tordecilla, Juan; Varas, Monica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marc (Lippincott Williams and Wilkins, 2008)
      Background: Severe sepsis is not clinically apparent during the first 24 hours of hospitalization in most children with cancer and febrile neutropenia (FN), delaying targeted interventions that could impact mortality. The ...
    • Santolaya de Pablo, María Elena; Alvarez, Ana M.; Avilés, Carmen L.; Becker, Ana; Cofré, José; Enríquez, N.; O'Ryan Gallardo, Miguel; Payá, Ernesto; Salgado, Carmen; Silva, Pamela; Tordecilla, Juan; Varas P., Mónica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marcela (2002)
      A risk prediction model for invasive bacterial infection (IBI) was prospectively evaluated among children presenting with cancer, fever, and neutropenia. The model incorporated assessment of 5 previously identified risk ...
    • Loyola, Paula; Tordecilla, Juan; Benadof, Dona; Yohannessen, Karla; Acuña, Mirta (Sociedad Chilena de Infectologia, 2015)
      © 2015, Sociedad Chilena de Infectologia. All rights reserved. Background: The isolation of vancomycin-resistant Enterococcus spp (ERV) has increased significantly within the last few years, along with the risk of infection ...
    • Villarroel, Milena; Avilés, Carmen L.; Silva, Pamela; Guzmán, Ana M.; Poggi, Helena; Álvarez, Ana M.; Becker, Ana; O'Ryan Gallardo, Miguel; Salgado, Carmen; Topelberg, Santiago; Tordecilla, Juan; Varas, Mónica; Viviani, Tamara; Zubieta, Marcela; Santolaya de Pablo, María Elena (Lippincott Williams and Wilkins, 2010)
      Background: Empiric antifungal treatment has become standard of care in children with cancer and prolonged fever and febrile neutropenia (FN), with the downside that it leads to significant over treatment. We characterized ...
    • Abu-Arja, Mohammad H.; Rojas del Río, Nicolás; Morales la Madrid, Andrés; Lassaletta, Álvaro; Moreno, Rosita; Valero, Miguel; Pérez, Verónica; Espinoza, Felipe; Fernández, Eduardo; Díaz, José; Santander, José; Tordecilla, Juan; Oyarce, Verónica; Kopp, Katherine; Bartels, Ute; Qaddoumi, Ibrahim; Finlay, Jonathan L.; Cáceres, Adrián; Espinoza, Ximena; Osorio, Diana S. (Oxford University Press, 2020)