Browsing by Author "XX568981"

Now showing items 61-80 of 89

    • Metal Nanoparticles for the Treatment and Diagnosis of Neurodegenerative Brain Diseases 
      Vio, Valentina; Marchant, María José; Araya, Eyleen; Kogan Bocian, Marcelo (Bentham Science Publishers Ltd., 2017)
      This review focuses on the application of metal nanoparticles in the diagnosis and treatment of Alzheimer's and Parkinson's diseases. Metal nanoparticles present interesting physicochemical properties that can be applied ...
    • Multifunctionalized gold nanoparticles with peptides targeted to gastrin-releasing peptide receptor of a ... 
      Hosta-Rigau, Leticia; Olmedo, Ivonne; Arbiol, Jordi; Cruz, Luis J.; Kogan Bocian, Marcelo; Albericio, Fernando (2010)
      Functionalization of gold nanoparticles (AuNPs) with both a targeting peptide (an analogue of the peptide Bombesin) and a drug peptide ligand (an analogue of the RAF peptide) with the aim of improving selectivity in the ...
    • Nanoparticle-mediated local and remote manipulation of protein aggregation 
      Kogan Bocian, Marcelo; Bastus, Neus G.; Amigo, Roger; Grillo-Bosch, Dolors; Araya, Eyleen; Turiel, Antonio; Labarta, Amilcar; Giralt, Ernest; Puntes, Víctor F. (AMER CHEMICAL SOC, 2006-01)
      The local heat delivered by metallic nanoparticles selectively attached to their target can be used as a molecular surgery to safely remove toxic and clogging aggregates. We apply this principle to protein aggregates, in ...
    • Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: Evolution toward ... 
      Bejarano, Julian; Navarro Márquez, Mario F.; Morales Zavala, Francisco; Morales, Javier O.; García Carvajal, Ivonne; Araya Fuentes, Eyleen; Flores, Yvo; Verdejo, Hugo E.; Castro, Pablo F.; Lavandero González, Sergio; Kogan Bocian, Marcelo (Ivyspring International Publisher, 2018)
      © Ivyspring International Publisher. Cardiovascular diseases are the leading cause of death worldwide. Despite preventive efforts, early detection of atherosclerosis, the common pathophysiological mechanism underlying ...
    • Nanopartículas de oro administradas en cerebro de rata : biodistribución y efectos sobre tejido 
      Riquelme Serey, Sebastián Andrés (Universidad de Chile, 2014)
      El uso de las nanopartículas de oro (NpO) ha adquirido importancia en los últimos años en la industria farmacéutica debido a que se han convertido en una herramienta promisoria para el diagnóstico y tratamiento de ...
    • Ni/Ni oxides nanoparticles with potential biomedical applications obtained by displacement of a ... 
      Rodríguez Llamazares, Saddys; Merchán, Juan; Olmedo, Ivonne; Marambio, Héctor; Muñoz, Juan; Jara, Paul; Sturm, Juan; Chornik, Boris; Peña, Octavio; Yutronic Sáez, Nicolás; Kogan Bocian, Marcelo (2008)
      A new synthesis and stabilization method was developed for paramagnetic nanoparticles composed of nickel and nickel oxides. Nickel/nickel oxides nanoparticles were synthesized by a method based on ligand displacement of ...
    • Obtención de conjugados de péptidos nanopartículas metálicas con potenciales aplicaciones biomédicas 
      Olmedo Alegría, Ivonne Odette (Universidad de Chile, 2007)
      Uno de los avances de la nanotecnología es la aplicación de nanopartículas metálicas (NPs) en el campo de la biomedicina. Estas NPs en presencia de campos magnéticos oscilantes (CMO) pueden absorber energía en forma ...
    • Occurrence of cadaverine in hairy roots of Brugmansia candida 
      Carrizo, Carla N.; Pitta Alvarez, Sandra I.; Kogan Bocian, Marcelo; Giulietti, Ana M.; Tomaro, María L. (PERGAMON-ELSEVIER SCIENCE LTD, 2001-07)
      The polyamine, cadaverine, was detected in transformed root cultures of Brugmansia candida (syn. Datuira candida), a Solanaceae which produces the tropane alkaloids scopolamine and hyoscyamine. To the best of our knowledge, ...
    • Organic and Inorganic Nanoparticles for Prevention and Diagnosis of Gastric Cancer 
      Oyarzún Ampuero, Felipe; Guerrero Hernández, Ariel; Hassan López, Natalia; Morales Valenzuela, Javier; Bollo Dragnic, Soledad; Corvalán Rodríguez, Alejandro; Quest, Andrew F. G.; Kogan Bocian, Marcelo (Bentham, 2015)
      Organic and inorganic nanoparticles show great potential for cancer diagnosis and treatment. Because gastric cancer (GC) represents the second most deadly type of neoplasia worldwide, continued research efforts by scientists ...
    • Peptide multifunctionalized gold nanorods decrease toxicity of beta-amyloid peptide in a Caenorhabditis ... 
      Morales Zavala, Francisco; Arriagada, Hector; Hassan, Natalia; Velasco, Carolina; Riveros Salvatierra, Ana; Álvarez, Alejandra R.; Minniti, Alicia N.; Rojas Silva, Ximena; Munoz, Luis L.; Vásquez Salfate, Rodrigo; Rodríguez, Katherine; Sánchez Navarro, Macarena; Giralt, Ernest; Araya, Eyleen; Aldunate, Rebeca; Kogan Bocian, Marcelo (Elsevier, 2017)
      The properties of nanometric materials make nanotechnology a promising platform for tackling problems of contemporary medicine. In this work, gold nanorods were synthetized and stabilized with polyethylene glycols and ...
    • Peptides and metallic nanoparticles for biomedical applications 
      Kogan Bocian, Marcelo; Olmedo, Ivonne; Hosta, Leticia; Guerrero, Ariel; Cruz, Luis; Albericio, Fernando (2007)
      In this review, we describe the contribution of peptides to the biomedical applications of metallic nanoparticles. We also discuss strategies for the preparation of peptide-nanoparticle conjugates and the synthesis of the ...
    • Péptido [beta]-amiloide (1-42): estudio de potenciales inhibidores y desarrollo de un nuevo método de ... 
      Fuente Salvat, Elizabeth de la (Universidad de Chile, 2012)
      La polimerización y agregación del péptido Aβ1-42 son procesos poco dilucidados hasta el momento, sin embargo, están fuertemente relacionados al desarrollo de la Enfermedad de Alzheimer, trastorno ...
    • Photothermal conversion efficiency and cytotoxic effect of gold nanorods stabilized with chitosan, alginate ... 
      Almada, M.; Leal Martínez, B. H.; Hassan, N.; Kogan Bocian, Marcelo; Burboa, M. G.; Topete, A.; Valdez, M. A.; Juarez, J. (Elsevier, 2017)
      Gold nanorods (GNR) use has been proposed in medical applications because of their intrinsic photothermal properties. However, the presence of CTAB molecules adsorbed onto the surface of GNRs results in a highly cytotoxic ...
    • Preparation and antibacterial properties of hybrid-zirconia films with silver nanoparticles 
      Azócar, Ignacio; Vargas, Esteban; Durán, Nicole; Arrieta, Abel; González, Evelyn; Pavez, Jorge; Kogan Bocian, Marcelo; Zagal Moya, José H.; Páez, Maritza (2012)
      The antimicrobial effect of incorporating silver nanoparticles (AgNps) into zirconia matrix-polyether glycol was studied. AgNps of 4-6 nm in size were synthesized using the inverse micelles method, and different doses of ...
    • Recubrimiento de nanoesferas de oro conjugadas al péptido CLPFFD-NH2 con poloxámeros para mejorar la ... 
      Miranda Rojas, Gustavo Adolfo (Universidad de Chile, 2014)
      En la actualidad existe gran interés en el uso de nanopartículas esféricas de oro (NPAu) para aplicaciones biomédicas. Éstas presentan propiedades ópticas que permiten la absorción y disipación de energía de manera local ...
    • Replacement of a proline with silaproline causes a 20-fold increase in the cellular uptake of a pro-rich peptide 
      Pujals, Sílvia; Fernández Carneado, Jimena; Kogan Bocian, Marcelo; Martínez, Jean; Cavelier, Florine; Giralt, Ernest (AMER CHEMICAL SOC, 2006-07-05)
      The results presented here show that elementary design enhancements have led to a 20-fold increase in the cellular uptake properties of a Pro-rich cell-penetrating peptide. These results are relevant not only due to the ...
    • Selective chemical etching for studying the frontside contact in thick film screen printedcrystalline p-type ... 
      Ferrada, P.; Portillo, C.; Cabrera, E.; Kopecek, R.; Poncebustos, M.; Kogan Bocian, Marcelo; Campo, V. del; Fuentealba, E. (Soc Chilena Quimica, 2015)
      Crystalline silicon solar cells are currently the leading technology in the photovoltaic market with no great expectable change in the shares. The scientific community works on the further development and improvements of ...
    • Selective nanodecoration of modified cyclodextrin crystals with gold nanorods 
      Herrera, Bárbara; Adura, Carolina; Yutronic Sáez, Nicolás; Kogan Bocian, Marcelo; Jara Vergara, Paul (Elsevier, 2013)
      Gold nanorods (AuNRs) stabilized by cetyltrimethylammonium bromide (CTAB) were deposited onto crystals of a-cyclodextrin (a-CD) inclusion compounds (ICs) that contained octanethiol (OT) as guest molecules. The nanodecoration ...
    • Sensing immobilized molecules of streptavidin on a silicon surface by maldi-tof mass spectrometry and ... 
      Araya, Eyleen; Kogan Bocian, Marcelo; Guell, Aleix G.; Escobar, Carlos A.; Sanz, Fausto (2014)
      A hydrogen-terminated Si (111) surface was modified to form an aminoterminated monolayer for immobilization of streptavidin. Cleavage of an N-(ω- undecylenyl)-phthalimide covered surface using hidrazine yields an amino ...
    • Smart polyaniline nanoparticles with thermal and photothermal sensitivity 
      Bongiovanni Abel, Silvestre; Molina, María A.; Rivarola, Claudia R.; Kogan Bocian, Marcelo; Barbero, César A. (IOP, 2014)
      Conductive polyaniline nanoparticles (PANI NPs) are synthesized by oxidation of aniline with persulfate in acid media, in the presence of polymeric stabilizers: polyvinilpyrrolidone (PVP), poly(N-isopropylacrylamide) ...