Now showing items 1-19 of 19

    • Vera, Felipe; Cortés, Víctor D.; Iturrra, Gabriel; Velásquez Silva, Juan; Maldonado Arbogast, Pedro; Couve Correa, Andrés (IEEE, 2017)
      As the use of the Internet grows every year, ecommerce’s usage does as well. There is a tough competition between companies to be able to attract customers to use their services.The design of a website is crucial to ...
    • González Roca, Carolina; Couve Correa, Andrés (Elsevier, 2014)
      Neurons are responsible for the generation and propagation of electrical impulses, which constitute the central mechanism of information transfer between the nervous system and internal or external environments. Neurons ...
    • Lazo, Óscar M.; González, Andrés; Ascaño, María; Kuruvilla, Rejji; Couve Correa, Andrés; Bronfman, Francisca (2013)
      Dendritic arborization of neurons is regulated by brain-derived neurotrophic factor (BDNF) together with its receptor, TrkB. Endocytosis is required for dendritic branching and regulates TrkB signaling, but how postendocytic ...
    • Koenig-Robert Leiva, Alexis Roger (Universidad de Chile, 2006)
      En el sistema nervioso, la transmisión del impulso nervioso entre neuronas se efectúa a través de la sinapsis. Éstas pueden ser de dos tipo, eléctricas y químicas. En estas últimas existen diversas proteínas que se asocian ...
    • Loyola Heufemann, Pablo; Martínez Azócar, Gustavo Adolfo; Muñoz, Kristofher; Velásquez Silva, Juan; Maldonado Grunwald, Pedro; Couve Correa, Andrés (Elsevier, 2015)
      Identifying the salient zones from Web interfaces, namely the Website Key Objects, is an essential part of the personalization process that current Web systems perform to increase user engagement. While several techniques ...
    • Vidal Álvarez, Roberto; Caballero, B.; Couve Correa, Andrés; Hetz Flores, Claudio (Bentham Science Publishers Ltd., 2011)
      A variety of neurological diseases including Huntington’s disease (HD), Alzheimer’s disease and Parkinson’s disease share common neuropathology, primarily featuring the presence of abnormal protein inclusions containing ...
    • Vergara, Rodrigo C.; Jaramillo Riveri, Sebastián; Luarte, Alejandro; Moenne Loccoz, Cristóbal; Fuentes Flores, Rómulo; Couve Correa, Andrés Oscar; Maldonado Arbogast, Pedro (Frontiers Media, 2020)
    • De Gregorio, Cristián; Delgado Arriagada, Ricardo; Ibacache, Andrés; Sierralta Jara, Jimena; Couve Correa, Andrés (Company of Biologists Ltd., 2017)
      Hereditary spastic paraplegias (HSPs) are characterized by spasticity and weakness of the lower limbs, resulting from length-dependent axonopathy of the corticospinal tracts. In humans, the HSP-related atlastin genes ...
    • Urra, Hery; Henríquez, Daniel R.; Cánovas, José; Villarroel Campos, David; Carreras Sureda, Amado; Pulgar, Eduardo; Molina, Emiliano; Hazari, Younis M.; Limia, Celia M.; Álvarez Rojas, Sebastián; Figueroa, Ricardo; Vidal, René L.; Rodríguez, Diego A.; Rivera, Claudia A.; Court, Felipe A.; Couve Correa, Andrés; Qi, Ling; Chevet, Eric; Akai, Ryoko; Iwawaki, Takao; Concha, Miguel L.; Glavic Maurer, Álvaro; González Billault, Christian; Hetz Flores, Claudio (Nature, 2018)
      Maintenance of endoplasmic reticulum (ER) proteostasis is controlled by a signalling network known as the unfolded protein response (UPR). Here, we identified filamin A as a major binding partner of the ER stress transducer ...
    • Salech Morales, Felipe; Couve Correa, Andrés; Michea Acevedo, Luis; Alvo Abodovsky, Miriam (Hospital Clínico Universidad de Chile, 2010)
      Klotho, a recently described gene, is mainly expressed in the kidney, and encodes a proteinnecessary for the activity of fibroblast growth factor receptors (FGFR), especially FGFR1. TheKlotho protein has two variants, a ...
    • Ramírez, Omar A.; Härtel, Steffen; Couve Correa, Andrés (SOC BIOLGIA CHILE, 2011)
      Neurons are highly polarized, but the trafficking mechanisms that operate in these cells and the topological organization of their secretory organelles a re still poorly understood. Particularly incipient is our knowledge ...
    • Vidal, René L.; Ramírez, Omar A.; Sandoval, Lisette; Koenig Robert, Roger; Haertel, Steffen; Couve Correa, Andrés (2007)
      The cytoskeleton and cytoskeletal motors play a fundamental role in neurotransmitter receptor trafficking, but proteins that link GABA(B) receptors (GABA(B)Rs) to the cytoskeleton have not been described. We recently ...
    • Vidal, René L.; Ramírez, Alfredo; Castro, Maite; Concha, Ilona I.; Couve Correa, Andrés (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-02-15)
      Marlin-1 is a GABAB receptor and Jak tyrosine kinase-binding protein that also associates with RNA and microtubules. In humans and rodents, expression of Marlin-1 is predominantly restricted to the brain, but expression ...
    • Preface 
      Couve Correa, Andrés; Kittler, Josef T. (Elsevier, 2014)
    • Couve Correa, Andrés; Hetz Flores, Claudio (Wiley-VCH Verlag, 2014)
      © 2014 The Authors. The efficient folding of membrane and secreted proteins relies on the unfolded protein response (UPR) to buffer fluctuations in the load of misfolded proteins. Although the UPR is thought to operate on ...
    • Couve Correa, Andrés; Hetz Flores, Claudio (Wiley-VCH Verlag, 2014)
      © 2014 The Authors. The efficient folding of membrane and secreted proteins relies on the unfolded protein response (UPR) to buffer fluctuations in the load of misfolded proteins. Although the UPR is thought to operate on ...
    • Luarte, Alejandro; Cornejo, Victor Hugo; Bertin, Francisca; Gallardo, Javiera; Couve Correa, Andrés (Wiley, 2018)
      The endoplasmic reticulum (ER) is highly conserved in eukaryotes and neurons. Indeed, the localization of the organelle in axons has been known for nearly half a century. However, the relevance of the axonal ER is only ...
    • Ramírez, Omar A.; Couve Correa, Andrés (Elsevier, 2011-04)
      Neurons are highly polarized cells whose dendrites and axons extend long distances from the cell body to form synapses that mediate neuronal communication. The trafficking of membrane lipids and proteins throughout the ...
    • Cuitino, Loreto; Godoy, Juan A.; Farías, Ginny G.; Couve Correa, Andrés; Bonansco, Christian; Fuenzalida, Marco; Inestrosa, Nibaldo C. (2010-06-23)
      GABAA receptors (GABAA-Rs) play a significant role in mediating fast synaptic inhibition and it is the main inhibitory receptor in the CNS. The role of Wnt signaling in coordinating synapse structure and function in the ...