Browsing by Author "XX575779"

Now showing items 1-18 of 18

    • 1,4-Dihydropyridines: Reactivity of nitrosoaryl and nitroaryl derivatives with alkylperoxyl radicals and ... 
      Valenzuela, V.; Santander, P.; Camargo Grandón, Rodrigo; Squella Serrano, Juan; López Alarcón, Camilo; Núñez Vergara, Luis (TAYLOR & FRANCIS, 2004-07)
      In the present paper, a direct quenching of radical species by a number of synthesized nitrosoaryl 1,4-dihydropyridines and their parent nitroaryl 1,4-dihydropyridines was determined in aqueous media at pH 7.4. These two ...
    • Analyses by GC-MS and GC-MS-MS of the hantzsch synthesis products using hydroxy- and methoxy-aromatic aldehydes 
      Núñez Vergara, Luis; Navarrete Encina, Patricio; Salas, S.; Conde, B.; Carbajo, J.; Squella Serrano, Juan; Camargo Grandón, Rodrigo (PERGAMON-ELSEVIER SCIENCE, 2007-05-09)
      El mass spectra of products of the dihydropyridine Hantzsch synthesis using hydroxy and methoxy aldehydes as starting materials are reported. The reaction products (C-4 hydroxy- and methoxyphenyl-1,4-dihydropyridines and ...
    • Analysis of 25 C NBOMe in Seized Blotters by HPTLC and GC–MS 
      Duffau, Boris; Camargo Grandón, Rodrigo; Kogan Bocian, Marcelo; Fuentes Pérez, Edwar; Cassels Niven, Bruce (Oxford University Press, 2016)
      Use of unauthorized synthetic drugs is a serious, forensic, regulatory and public health issue. In this scenario, consumption of drug-impregnated blotters is very frequent. For decades, blotters have been generally impregnated ...
    • Detection of tamoxifen metabolites by GC-MSD 
      Báez Guerrero, Hernán; Camargo Grandón, Rodrigo; Osorio, H,; Umpierrez, F. (PRESTON PUBLICATIONS INC, 2004-11)
      Tamoxifen is an antiestrogen used in the adjuvant endocrine therapy of early breast cancer and malignant breast disorders. It is also used in women with anovulatory infertility caused by its stimulating effect on the ...
    • Drugs in prehistory: chemical analysis of ancient human hair 
      Báez Guerrero, Hernán; Camargo Grandón, Rodrigo; Benavente, M. A.; Kintz, P.; Castro Domínguez, Mario; Cirimele, V.; Thomas, C. (ELSEVIER SCI IRELAND LTD, 2000-02-28)
      Concern about drug abuse in modem populations has led to the development of specific methods for identification of cocaine, opiates and cannabis in human hair. Drug use in prehistory can provide indirect evidence of ...
    • Electrochemical and EPR characterization of 1,4-dihydropyridines. Reactivity towards alkyl radicals 
      Núñez Vergara, Luis; López Alarcón, Camilo; Navarrete Encina, Patricio; Atria Salas, Ana María; Camargo Grandón, Rodrigo; Squella Serrano, Juan (TAYLOR & FRANCIS LTD, 2003)
      This work reports the electrochemical oxidation of a series of three synthesized 4-substituted-1,4-dihydropyridine derivatives in different electrolytic media. Also, an EPR characterization of intermediates and the reactivity ...
    • Electrochemical oxidation of C4-vanillin- and C4-isovanillin-1,4-dihydropyridines in aprotic medium: ... 
      Salazar González, Ricardo Andrés; Navarrete Encina, Patricio; Camargo Grandón, Rodrigo; Squella Serrano, Juan; Núñez Vergara, Luis (ELSEVIER SCIENCE SA, 2008-10-01)
      This work reports the electrochemical oxidation of two new synthetic C4-vanillin and -isovanillin-1,4-dihydropyridines in aprotic medium. Its reactivity with alkylperoxyl radicals ABAP-derived at pH 7.4 is also studied. ...
    • Electrolytic oxidation of C4-nitrofuryl 1,4-dihydropyridines in nonaqueous medium 
      Núñez Vergara, Luis; Salazar González, Ricardo Andrés; Navarrete Encina, Patricio; Camargo Grandón, Rodrigo; Yáñez Soto, Claudia; Squella Serrano, Juan (ELECTROCHEMICAL SOC, 2007)
      A study of the electrolytic oxidation of three new C-4 nitrofuryl 1,4-dihydropyridines in nonaqueous aprotic medium is presented. Controlled-potential electrolysis (CPE) in dimethylformamide +0.1 M tetrabutyl-ammonium ...
    • Gas chromatography/mass spectrometric study of non-commercial C-4-substituted 1,4-dihydropyridines and their ... 
      López Alarcón, Camilo; Squella Serrano, Juan; Núñez Vergara, Luis; Báez Guerrero, Hernán; Camargo Grandón, Rodrigo (JOHN WILEY, 2002)
      A gas chromatography/mass spectrometry (GC/MS) method for the qualitative and quantitative determination of the calcium-channel antagonists C-4-substituted 1,4-dihydropyridines, and their corresponding N-ethyl derivatives, ...
    • One- and Two-Dimensional NMR in the Structure Determination of 3B-Acetoxy-17B,21B-epoxyhopane from Centaurea ... 
      Hartmann, Rudolf; Breitmaier, Eberhard; Camargo Grandón, Rodrigo; Negrete Córdova, Rosa; Backhouse Erazo, Nadine; Delporte Vergara, Carla; Cassels Niven, Bruce (Johann Ambrosius Barth, 1992-03-27)
    • Oxidation of 4-(3-Indolyl)- and 4-(5-Indolyl)-1,4-dihydropyridines in Aprotic and Protic Media: Reactivity ... 
      Salazar González, Ricardo Andrés; Navarrete Encina, Patricio; Camargo Grandón, Rodrigo; Squella Serrano, Juan; Núñez Vergara, Luis (ELECTROCHEMICAL SOC INC, 2008)
      Electrochemical oxidation of 4-(3-indolyl)- and 4-(5-indolyl)-1,4-dihydropyridines (DHPs) in aprotic and protic media is reported. Also, the reactivity of compounds toward alkylperoxyl radicals 2,2'-azobis-(2-amidinopropane) ...
    • Oxidation of Hantzsch 1,4-dihydropyridines of pharmacological significance by electrogenerated superoxide 
      Ortíz Yáñez, María Eugenia; Núñez Vergara, Luis; Camargo Grandón, Rodrigo; Squella Serrano, Juan (KLUWER ACADEMIC/PLENUM PUBL, 2004-03)
      The final pyridine derivatives were separated and identified by gas chromatography/ mass spectrometry (GC-MS). The intermediates, anion dihydropyridine and the HO2./HO2- species, were observed from voltammetric studies and ...
    • Reactivity of 1,4-dihydropyridines toward alkyl, alkylperoxyl radicals, and ABTS radical cation 
      López Alarcón, Camilo; Navarrete Encina, Patricio; Camargo Grandón, Rodrigo; Squella Serrano, Juan; Núñez Vergara, Luis (AMER CHEMICAL SOC, 2003-02)
      A series of C4-substituted 1,4-dihydropyridines (DHP) with either secondary or tertiary nitrogen in the dihydropyridine ring were synthesized. All of these compounds together with some commercial DHP derivatives were tested ...
    • Reactivity of 1,4-dihydropyridines toward SIN-1-derived peroxynitrite 
      López Alarcón, Camilo; Speisky Cosoy, Hernán; Squella Serrano, Juan; Olea Azar, Claudio; Camargo Grandón, Rodrigo; Núñez Vergara, Luis (KLUWER ACADEMIC/PLENUM PUBL, 2004-10)
      Purpose. To study the reactivity of C4-substituted 1,4-dihydropyridines (1,4-DHP), with either secondary or tertiary nitrogen in the dihydropyridine ring, toward SIN-1-derived peroxynitrite in aqueous media at pH 7.4. Methods. ...
    • Reactivity of C4-indolyl substituted 1,4-dihydropyridines toward superoxide anion (O-2((center dot)under-bar)) ... 
      Salazar González, Ricardo Andrés; Navarrete Encina, Patricio; Squella Serrano, Juan; Camargo Grandón, Rodrigo; Núñez Vergara, Luis (JOHN WILEY & SONS LTD, 2009-06)
      Reactivity of two new C4-indolyl substituted 1,4-dihydropyridines (1,4-DHPs) toward superoxide anion (O-2) in dimethylsulfoxide (DMSO) is reported. Reactivity was followed by electrochemical and spectroscopic techniques. ...
    • Simultaneous determination of melatonin and pyridoxine in tablets by gas chromatography-mass spectrometry 
      Núñez Vergara, Luis; Squella Serrano, Juan; Sturm Schaub, Juan; Báez Guerrero, Hernán; Camargo Grandón, Rodrigo (PERGAMON-ELSEVIER SCIENCE, 2001-12)
      A gas chroma tographic-mass spectrometric (GC-MS) method for the qualitative and quantitative determination of melatonin plus pyridoxine commercial tablets is described. Melatonin and pyridoxine were simultaneously determined ...
    • Steroids, a lignam and a flavonoid from centaurea melitensis L. 
      Negrete Córdova, Rosa; Backhouse Erazo, Nadine; Prieto, P.; Menas, N.; Camargo Grandón, Rodrigo; Cassels Niven, Bruce; Brehmaier, E.; Hartmann, R. (Cêntre d'Etude des Plantes Médicinales, 1989)
      P.Sitoslerol 3-0·P.O-glucosidc. P.sitoslerol, stigmaSlcrol, th,' ligoan arcllln, and lit.: (lmelhoxylaled fiavone hispiculin wcre isolatcd from a chloroform c:~lra•.t "r (h •. aerial pans (Ir (','/IIcm't'a m.'lilt!n.fi~l.. ...
    • Structural effects on the reactivity 1,4-dihydropyridines with alkylperoxyl radicals and ABTS radical cation 
      Yáñez Soto, Claudia; Lápez Alarcón, Camilo Ignacio; Camargo Grandón, Rodrigo; Valenzuela, V.; Squella Serrano, Juan; Núñez Vergara, Luis (PERGAMON-ELSEVIER SCIENCE, 2004-05-01)
      A series of eight commercial C-4 substituted 1,4-dihydropyridines and other synthesized related compounds were tested for direct potential scavenger effect towards alkylperoxyl radicals and ABTS radical cation in aqueous ...