Browsing by Author "XX577765"

Now showing items 1-20 of 21

    • A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis 
      Díaz Jiménez, David; Núñez, Lucía; Fuente, Marjorie de la; Dubois Camacho, Karen; Sepulveda, Hugo; Montecino, Martin; Torres Riquelme, Alejandro; García González, Paulina; Chnaiderman Figueroa, Jonás; Vossenkamper, Anna; MacDonald, Thomas T.; Simian, Daniela; González Burgos, María Julieta; Cidlowski, John A.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Nature Publishing Group, 2017)
      The ST2/IL33 signalling pathway has been associated with ulcerative colitis (UC). ST2, encoded by the IL1RL1 gene, is expressed as both a membrane-anchored receptor (ST2L) activated by IL33 and as a soluble receptor (sST2) ...
    • An update on the pathogenesis of celiac disease Enfermedad celíaca y su patogenia 
      Herrera, María José; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2009)
      Celiac disease (CD), with a 1% world-wide prevalence, is an enteropathy caused by an autoimmune reaction to gluten in genetically susceptible individuals, that codify for histocompatibility molecules HLA DQ-2/DQ-8. From ...
    • Análisis de polimorfismos genéticos del gen NOD2/CARD 15 y TLR4, asociados a enfermedades Inflamatorias ... 
      Peralta Bondi, Alexis Luis (Universidad de ChilePrograma Cybertesis, 2007)
      La Enfermedad de Crohn (EC) y la Colitis Ulcerosa (CU) enfermedades inflamatorias intestinales (EII) multifactoriales que presentan una relación genética importante. Recientemente se han descrito polimorfismos en los ...
    • Barostato rectal en el síndrome de intestino irritable 
      Defilippi Guerra, Claudia; Quera Pino, Rodrigo; Madrid Silva, Ana; Defilippi Cafri, Carlos; Valenzuela Escobar, Jorge (2006)
      Background: Many patients with irritable bowel syndrome (IBS) have lowered sensory thresholds to rectal distention when compared to control subjects, a phenomenon called visceral hypersensitivity. Aim: To investigate the ...
    • Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease 
      Beltrán, Caroll J.; Núñez, Lucía E.; Díaz Jiménez, David; Farfán, Nancy; Candia, Enzo; Heine, Claudio; López, Francisco; González Burgos, María Julieta; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (2010)
      Background: ST2 has been proposed to be a regulator of inflammation and Th1/Th2 balance. ST2L is the IL-33 membrane receptor and belongs to the IL-1R family. The soluble variant, ST2s, is identical to the extracellular ...
    • Dendritic Cells and Toll-Like Receptors 2 and 4 in the Ileum of Crohn's disease patients 
      Silva, Manuel A.; Quera Pino, Rodrigo; Valenzuela Escobar, Jorge; Salim, Sa’ad Y.; Söderholm, Johan D.; Perdue, Mary H. (SPRINGER, 2008-07)
      We investigated myeloid-dendritic cell (DC) marker and Toll-like receptor (TLR)-2 and 4 distributions in ileal samples from Crohn’s disease (CD) patients (n = 14) and controls (n = 13). In controls, no TLR-2+ cells ...
    • Enfermedad inflamatoria intestinal: Una mirada inmunológica 
      Sepúlveda, Sofía E.; Beltrán Muñoz, Caroll; Peralta, Alexis; Rivas, Paola; Rojas, Néstor; Figueroa, Carolina; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (SOC MEDICA SANTIAGO, 2008-03)
      Inflammatory bowel diseases (IBD) are inflammatory diseases with a multifactorial component that involve the intestinal tract. The two relevant IBD syndromes are Crohn’s disease (CD) and ulcerative colitis (UC). One ...
    • Enfermedades inflamatorias intestinales: Experiencia de dos centros chilenos 
      Figueroa C., Carolina; Quera Pino, Rodrigo; Valenzuela Escobar, Jorge; Jensen Benítez, Christian (Sociedad Médica de Santiago, 2005-10)
      The incidence of Inflammatory Bowel Disease (IBD) has increased, particularly in the developed world, and probably also in Chile. Aim: To report our experience with a large group of patients from two medical centers, ...
    • Glucocorticosteroid therapy in inflammatory bowel diseases: from clinical practice to molecular biology 
      Dubois Camacho, Karen; Ottum, Payton A.; Franco Muñoz, Daniel; Fuente, Marjorie de la; Torres Riquelme, Alejandro; Díaz Jiménez, David; Olivares Morales, Mauricio; Astudillo, Gonzalo; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Baishideng Publishing Group, 2017)
      Inflammatory bowel diseases (IBDs), such as ulcerative colitis and Crohn's disease, are chronic pathologies associated with a deregulated immune response in the intestinal mucosa, and they are triggered by environmental ...
    • IL-23R Arg381Gln polymorphism in Chilean patients with inflammatory bowel disease 
      Venegas Santos, Mauricio; Beltrán Muñoz, Caroll; Alvarez, Luis; Castro, Ariel; Torres, Tamara; Leal, Andrea D.; Lahsen, Francisca M.; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2008-12)
      Crohn’s disease (CD) and ulcerative colitis (UC) are multifactorial diseases with a genetic background. Recent results have shown that a non-synonymous, single nucleotide polymorphism (rs11209026, c.1142G>A, p.Arg381Gln) ...
    • Inflammatory bowel diseases: An immunological approach Enfermedad inflamatoria intestinal: Una mirada inmunológica 
      Sepúlveda, Sofía E.; Beltrán, Caroll J.; Peralta, Alexis; Rivas, Paola; Rojas, Néstor; Figueroa, Carolina; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (2008)
      Inflammatory bowel diseases (IBD) are inflammatory diseases with a multifactorial component that involve the intestinal tract. The two relevant IBD syndromes are Crohn's disease (CD) and ulcerative colitis (UC). One factor ...
    • NOD2/CARD15 and Toll-like 4 receptor gene polymorphism in Chilean patients with inflammatory bowel disease 
      Figueroa, Carolina; Peralta, Alexis; Herrera Cisterna, Luisa; Castro, Pedro; Gutiérrez, Andrea; Valenzuela Escobar, Jorge; Aguillón Gutiérrez, Juan Carlos; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (JOHN LIBBEY EUROTEXT LTD, 2006-06)
      Crohn's disease (CD) and ulcerative colitis (UC) are multifactorial diseases with a genetic background. Genes related to the innate immune response have been observed to be involved. Polymorphisms of Toll-like receptor 4 ...
    • Octreótido, tratamiento endoscópico o ambos en la hemorragia variceal activa en pacientes cirróticos: estudio ... 
      Silva P., Guillermo; Quera Pino, Rodrigo; Fluxá G., Fernando; Sanhueza B., Edgar; Segovia M., Roberto; Brahm Barril, Javier; Muñoz, Cristián; Morales Barria, Antonio; Muñoz Clavijo, Lorena; Urzúa F., Luis; Biagini A., Leandro (SOC MEDICA SANTIAGO, 2004-03)
      Acute variceal bleeding in cirrhotic patients is an emergency with a high risk of rebleeding and death. Endoscopic procedures such as sclerotherapy or banding, combined or not with drugs such as octreotide could be ...
    • Peripheral cytokine profile in Chilean patients with Crohn's disease and ulcerative colitis 
      Beltrán, Caroll J.; Candia, Enzo; Erranz, Benjamín; Figueroa, Carolina; Gonzalez, Maria J.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (2009)
      Crohn's disease (CD) and ulcerative colitis (UC) belong to the group of inflammatory bowel diseases (IBD), with complex ethiopathogenic factors that include an unbalanced immune and inflammatory response to commensal and ...
    • Peripheral cytokine profile in Chilean patients with Crohn's disease and ulcerative colitis (European ... 
      Beltrán, Caroll J.; Candia, Enzo; Erranz, Benjamín; Figueroa, Carolina; Gonzalez, Maria J.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (2009)
    • Polimorfismo del gen de la tiopurina S-metiltransferasa en donantes de sangre de un hospital universitario 
      Alvarez L., Luis; Venegas Santos, Mauricio; Larrondo Lillo, Milton; Becerra B., Natalia; Castro L., Ariel; Quera Pino, Rodrigo (2009)
      Background: Thiopurine S-methyltransferase (TPMT) is a cytosolic enzyme that catalyzes the S-methylation of 6-mercaptopurine and azathioprine. Lowactivity phenotypes are correlated with polymorphism in the TPMT gene. ...
    • Small Intestinal Clustered Contractions and Bacterial Overgrowth: A Frequent Finding in Obese Patients 
      Quera Pino, Rodrigo; Poniachik Teller, Jaime; Defilippi Cafri, Carlos; Madrid Silva, Ana (Springer, 2011)
      Background Small intestinal bacterial overgrowth (SIBO) has been observed in several disorders of the gastrointestinal tract. Studies have shown abnormalities of motor function in obese patients, and there is ...
    • Sobrecrecimiento bacteriano intestinal 
      Quera Pino, Rodrigo; Quigley, Eamonn M. M.; Madrid Silva, Ana (Sociedad Médica de Santiago, 2005-11)
      Small intestinal bacterial overgrowth (SIBO) is characterized by nutrient malabsorption, associated with an excessive number of bacteria in the proximal small intestine. Unfortunately, the diagnosis of bacterial overgrowth ...
    • Soluble ST2 is a sensitive clinical marker of ulcerative colitis evolution 
      Díaz Jiménez, David; De la Fuente, Marjorie; Dubois Camacho, Karen; Landskron, Glauben; Fuentes, Janitza; Pérez, Tamara; González Burgos, María Julieta; Simian, Daniela; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2016)
      Background: The ST2/IL-33 pathway has been related to ulcerative colitis (UC), and soluble ST2 (sST2), to disease severity. We tested the potential usefulness of sST2 as a predictive marker of treatment response and patients' ...
    • Soluble ST2: A new and promising activity marker in ulcerative colitis 
      Díaz Jiménez, David; Núñez, Lucía E.; Beltrán, Caroll J.; Candia, Enzo; Suazo, Cristóbal; Álvarez Lobos, Manuel; González Burgos, María Julieta; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2011)
      AIM: To correlate circulating soluble ST2 (sST2) levels with the severity of ulcerative colitis (UC) and serum levels of pro-inflammatory cytokines, and to demonstrate the predictive power of sST2 levels for differentiation ...