Browsing by Author "XX580402"

Now showing items 1-7 of 7

    • Chromosomal size conservation through the cell cycle supports karyotype stability in Trypanosoma cruzi 
      Galindo Díaz, Mario; Sabaj Diez, Valeria; Espinoza, Ingrid; Toro, Gabriela Cecilia; Búa, Jaqueline; Grenet, Jose; López Solís, Remigio; Ruiz, Andres Mariano; Galanti Garrone, Norbel (ELSEVIER SCIENCE BV, 2007-05)
      The Trypanosoma cruzi karyotype shows an extensive chromosomal size polymorphism. Absence of condensed mitotic chromosomes and chromatin fragility are characteristic features of T. cruzi which would allow DNA breaks and ...
    • Echinococcus granulosus: Cellular territories and morphological regions in mature protoscoleces 
      Galindo Díaz, Mario; Schadebrodt, Gloria; Galanti Garrone, Norbel (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008-08)
      Basic aspects of the generation, structure and function of Echinococcus granulosus protoscoleces are unknown. We review the work done on the structure and ultrastructure of the E. granulosus protoscolex and provide new ...
    • Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and ... 
      Araya López, Héctor; Sepulveda, Hugo; Lizama, Carlos O.; Vega Villa, Oscar; Jerez, Sofia; Briceño, Pedro F.; Thaler, Roman; Riester, Scott M.; Antonelli Anativia, Marcelo; Salazar Onfray, Flavio; Rodríguez Vives, Juan Pablo; Moreno, Ricardo D.; Montecino, Martín; Charbonneau, Martine; Dubois, Claire; Galindo Díaz, Mario; Stein, Gary; van Wijnen, Andre (Wiley-Liss Inc., 2018)
      Osteoblast differentiation is controlled by transcription factor RUNX2 which temporally activates or represses several bone-related genes, including those encoding extracellular matrix proteins or factors that control ...
    • Genomic Promoter Occupancy of Runt-related Transcription Factor RUNX2 in Osteosarcoma Cells Identifies Genes ... 
      van der Deen, Margaretha; Akech, Jacqueline; Lapointe, David; Gupta, Sneha; Young, Daniel W.; Montecino, Martín A.; Galindo Díaz, Mario; Lian, Jane B.; Stein, Janet L.; Stein, Gary S.; van Wijnen, Andre J. (2012-02-10)
      Runt-related transcription factors (RUNX1, RUNX2, and RUNX3) are key lineage-specific regulators of progenitor cell growth and differentiation but also function pathologically as cancer genes that contribute to tumorigenesis. ...
    • Mitotic Inheritance of mRNA Facilitates Translational Activation of the Osteogenic-Lineage Commitment Factor ... 
      Varela Figueroa, Nelson; Aránguiz Quezada, Katherine Alejandra; Lizama, Carlos; Sepúlveda, Hugo; Antonelli Anativia, Juan; Thaler, Román; Moreno, Ricardo D.; Montecino, Martín; Stein, Gary S.; Van Wijnen, Andre; Galindo Díaz, Mario (Wiley-Blackwell, 2016)
      Epigenetic mechanisms mediate the acquisition of specialized cellular phenotypes during tissue development, maintenance and repair. When phenotype-committed cells transit through mitosis, chromosomal condensation counteracts ...
    • Transactivation activity and nucleocytoplasmic transport of β-catenin are independently regulated by its ... 
      Maturana, J.; Niechi, I.; Silva, E.; Huerta, H.; Cataldo, R.; Härtel, Steffen; Barros, L.; Galindo Díaz, Mario; Tapia Pineda, Julio (Elsevier, 2015)
      The key protein in the canonicalWnt pathway is β-catenin, which is phosphorylated both in absence and presence ofWnt signals by different kinases. Upon activation in the cytoplasm, β-catenin can enter into the nucleus ...
    • Wnt/β catenin signaling activates expression of the bone-related transcription factor RUNX2 in select human ... 
      Vega, Oscar A.; Lucero, Claudia M. J.; Araya, Héctor F.; Jerez, Sofía; Tapia Pineda, Julio; Antonelli Anativia, Juan; Salazar Onfray, Flavio; Heras Aliciardi, Facundo las; Thaler, Roman; Riester, Scott M.; Stein, Gary S.; van Wijnen, Andre J.; Galindo Díaz, Mario (Wiley, 2017)
      Osteosarcoma is the most common malignant bone tumor in children and adolescents. Metastasis and poor responsiveness to chemotherapy in osteosarcoma correlates with over-expression of the runt-related transcription factor ...