Browsing by Author "XX593555"
Now showing items 1-20 of 21
-
Cruz, Pamela; Epuñán, María José; Ramírez, María Eugenia; Torres, Cristian G.; Valladares Boasi, Luis; Sierralta, Walter D. (2012)The principal aim of this study was to analyze in estrogen receptor-positive MCF7 cells the response of three estrogen-dependent proteins to 27-hydroxycholesterol (27OHC), a major circulating cholesterol metabolite. ...
-
Torres, Cristian G.; Ramírez, María Eugenia; Cruz, Pamela; Epuñán, María José; Valladares Boasi, Luis; Sierralta, Walter D. (2011)A decrease in the expression of E-cadherin and β-catenin, paralleling the loss of adherens junction complex, was observed in MCF7 cells exposed for longer than 48 h to 2 μM27-hydroxycholesterol (27OHC), indicating an ...
-
Sierralta, Walter D.; Epuñán, María José; Reyes, José M.; Valladares Boasi, Luis; Andersen, Thomas T.; Bennett, James A.; Jacobson, Herbert I.; Pino, Ana M. (2008)This study was aimed to obtain additional information on the activity of a cyclized 9-amino acid peptide (cP) containing the active site of alpha fetoprotein, which inhibits the estrogen-stimulated proliferation of tumor ...
-
Sáez Briones, Patricio; Soto Moyano, Rubén; Burgos, Héctor; Castillo, Amparo; Valladares Boasi, Luis; Morgan Sabat, Carlos; Pérez, Hernán; Barra, Rafael; Constandil, Luis; Laurido, Claudio; Hernández, Alejandro (Elsevier, 2015)Moderate reduction in dietary protein composition of pregnant rats from 25% to 8% casein, calorically compensated by carbohydrates, has been described as a ‘‘hidden malnutrition’’ because it does not alter body and brain ...
-
Alvarado, Manuel; Serrano, Edison; Sánchez, Juan; Valladares Boasi, Luis (Universidad Católica de Valparaíso, 2015)A detailed study of gametes development and characterization of plasma sex steroid hormones during the maturation cycle was performed for the first time in the southern hake (Merluccius australis). Fish were caught in the ...
-
Opazo Salas, Rafael; Valladares Boasi, Luis; Romero Ormazábal, Jaime (Universidad Católica de Valparaíso, 2017)Variable individual growth rate is a phenomenon observed in fish cohorts that influences the aquaculture performance and fish cohort ecological viability. Our aim was to compare gene expression patterns of key growth genes ...
-
Plaza, F.; Gabler Neale, Fernando; Romero Osses, Carmen; Vantman Bretschneider, David; Valladares Boasi, Luis; Vega Blanco, María Margarita (ELSEVIER, 2010-12)The changes in endometrial homeostasis found in women with polycystic ovarian syndrome (PCOS) could be associated with alterations in the intracrine metabolism of steroid hormones. The uptake of dehydroepiandrosterone-sulphate ...
-
Torres, Crístian; Antileo, Elmer; Epuñán, María José; Pino, Ana María; Valladares Boasi, Luis; Sierralta, Walter (PROFESSOR D A SPANDIDOS, 2008-06)A cyclic peptide derived from the active domain of α-fetoprotein (AFP) significantly inhibited the proliferation of MCF7 cells stimulated with the epidermal growth factor (EGF) or estradiol (E2). The action of these ...
-
Muñoz, Y. C.; Gomez, G. I.; Moreno, M.; Solis, C. L.; Valladares Boasi, Luis; Velarde, V. (2012)The steroid hormone dehydroepiandrosterone (DHEA), suggested to be a cardioprotector, prevents platelet aggregation in healthy humans. This hormone is reduced in postmenopausal women by 60% of its normal value. Platelets ...
-
Plaza Parrochia, Francisca; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (Elsevier, 2017)Normal endometrial function requires of cell proliferation and differentiation; therefore, disturbances in these processes could lead to pathological entities such as hyperplasia and endometrial adenocarcinoma, where cell ...
-
Guerrero-Bosagna, Calos M.; Sabat Kirkwood, Alejandro Pablo; Valdovinos, Fernanda S.; Valladares Boasi, Luis; Clark, Susan J. (BioMed Central, 2008-09-15)Background: Developmental effects of exposure to endocrine disruptors can influence adult characters in mammals, but could also have evolutionary consequences. The aim of this study was to simulate an environmental ...
-
Plaza Parrochia, Francisca; Poblete, Cristian; Gabler Neale, Fernando; Carvajal Gavilán, Rodrigo; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (Elsevier, 2015)Intracrinology mechanism involves the metabolism of steroids in peripheral tissues, such as DHEA, to molecules with estrogenic or androgenic activity. Proliferation rate of endometria from Polycystic Ovary Syndrome women ...
-
Núñez, Héctor; Ruiz, Samuel; Soto Moyano, Rubén; Navarrete, Mario; Valladares Boasi, Luis; White Ortiz, Allan; Pérez, Hernán (ELSEVIER IRELAND LTD, 2008-12-19)Prenatal undernutrition induces a variety of cardiovascular alterations inmammalswhenadults, including hypertension and hypercortisolism, which are thought to be caused by decreased glucocorticoid feedback control of the ...
-
Estay, Francisco; Neira Roa, Roberto; Díaz, Nelon F.; Valladares Boasi, Luis; Torres, Alfredo (1998)The gametogenesis of a 2-year-old coho salmon broodstock population cultured in a fish farm in southern Chile was studied. Gonadosomatic index (GSI), microscopic gonadal traits, and serum levels of estradiol-17b(E2), ...
-
Bacallao, Ketty; León, L.; Gabler Neale, Fernando; Soto, E.; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (PERGAMON-ELSEVIER SCIENCE LTD, 2008-05)The aim of the present investigation was to study whether the endocrinological status of women bearing polycystic ovarian syndrome (PCOS) affects the endometrial in situ steroid metabolism. For this purpose, we evaluated ...
-
Soto Moyano, Rubén; Burgos, Héctor; Flores, Francisco; Valladares Boasi, Luis; Sierralta, Walter; Fernández Hidalgo, Víctor; Pérez, Hernán; Hernández, Paula; Hernández, Alejandro (PERGAMON-ELSEVIER SCIENCE LTD, 2006-10)Melatonin has been shown to inhibit long-term potentiation (LTP) in hippocampal slices of rats. Since LTP may be one of the main mechanisms by which memory traces are encoded and stored in the central nervous system, it ...
-
Soto Moyano, Rubén; Valladares Boasi, Luis; Sierralta, Walter; Pérez, Hernán; Mondaca, Mauricio; Fernández, Víctor; Burgos, Héctor; Hernández Hidalgo, Alejandro (BLACKWELL PUBLISHING LTD, 2005-06)Mild reduction in the protein content of the mother's diet from 25 to 8% casein, calorically compensated by carbohydrates, does not alter body and brain weights of rat pups at birth, but leads to significant enhancements ...
-
Sierralta, Walter; Hernández, Alejandro; Valladares Boasi, Luis; Pérez, Hernán; Mondaca, Mauricio; Soto Moyano, Rubén (PERGAMON-ELSEVIER SCIENCE LTD, 2006-05-15)Mild reduction in the protein content in the diet of pregnant rats from 25 to 8% casein, calorically compensated by carbohydrates, does not alter body and brain weights of rat pups at birth, but results in significant ...
-
Plaza Parrochia, Francisca; Oróstica Arévalo, María Lorena; García, Paula; Vera, Carolina; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (SAGE Publications Inc, 2017)Proliferation in endometria of women with polycystic ovarian syndrome (PCOS) is increased, similar to the biosynthesis of androstenediol (estrogenic metabolite). As previously shown, in human endometrial cells, androstenediol ...
-
Navarrete, Mario; Núñez, Héctor; Ruiz, Samuel; Soto Moyano, Rubén; Valladares Boasi, Luis; White Ortiz, Allan; Pérez, Hernán (ELSEVIER IRELAND LTD, ELSEVIER HOUSE, 2007-05)Prenatal undernutrition is known to disturb the hypothalamo-pituitary-adrenal (HPA) axis, possibly through the programming of decreased expression of hypothalamic and pituitary glucocorticoid receptors. To test this ...