Now showing items 1-14 of 14

    • Maya Arango, Juan; Rodríguez, Andrés; Pino, Laura; Pabón, Adriana; Ferreira, Jorge; Pavani, Mario; Repetto Scaramelli, Yolanda; Morello Casté, Antonio (Society of Biology of Chile, 2004)
      Proteins rich in sulfhydryl groups, such as metallothionein, are present in several strains of the parasite Trypanosoma cruzi, the etiological agent of Chagas' disease. Metallothionein-like protein concentrations ranged ...
    • Maya Arango, Juan; Repetto Scaramelli, Yolanda; Agosín, Moisés; Ojeda, José Manuel; Tellez, Rowena; Gaule, Carlos; Morello Casté, Antonio (1997)
    • Rivas, Pilar; Cassels Niven, Bruce; Morello Casté, Antonio; Repetto Scaramelli, Yolanda (1999)
      Several β-carboline (9H-pyrido-[3,4-b]-indole) alkaloids were evaluated for in vitro trypanosomicidal activity against Trypanosoma cruzi epimastigotes belonging to two different strains (Tulahuen and LQ) showing different ...
    • Lemus, David; Illanes, Julio; Fuenzalida, Marcela; Repetto Scaramelli, Yolanda; De La Vega, Yolanda Paz; Blańquez, Maria José (1987)
      The developmental processes related to odontogenesis are similar in all vertebrates and they occur during embryogenesis. The dental papilla can exercises directive morphogenetic role on epithelia of different phylogenetic ...
    • Olea Azar, Claudio; Rigol Olsen, Carolina; Opazo, L.; Morello Casté, Antonio; Maya Arango, Juan; Repetto Scaramelli, Yolanda; Aguirre, G.; Cerecetto, Hugo; Di Maio, R.; González, M.; Porcal, Williams (SOCIEDAD CHILENA DE QUIMICA, 2003-12)
      The Electron Spin Resonance (ESR) spectra of radicals obtained from two new potential antitrypanosomal drugs by Trypanosoma cruzi reduction were analyzed. DMPO Spin Trapping was used to investigate the possible formation ...
    • Repetto Scaramelli, Yolanda; Opazo, Eduardo; Maya Arango, Juan; Agosin, Moises; Morello Casté, Antonio (Elsevier Inc., 1996)
      Glutathione (GSH), trypanothione (T(SH)2) and glutathionyl spermidine (GSH-SP) concentrations were determined in the Tulahuen and LQ strains and the DM 28c clone of Trypanosoma cruzi. The concentrations of GSH, T(SH)2 and ...
    • Núñez Vergara, Luis; Squella Serrano, Juan; Bollo Dragnic, Soledad; Morello Casté, Antonio; Repetto Scaramelli, Yolanda; Aldunate, Jorge; Letelier, María E. (1997)
      A series of nitro aryl 1,4-dihydropyridine derivatives produced inhibition of both cell growth and oxygen consumption on Tulahuen and LQ strains, and clone Dm 28c of epimastigotes of Trypanosoma cruzi. Nicardipine was found ...
    • Olea Azar, Claudio; Rigol Olsen, Carolina; Mendizábal Emaldía, Fernando; Cerecetto, Hugo; Di Maio, R.; González, Mercedes; Porcal, Williams; Morello Casté, Antonio; Repetto Scaramelli, Yolanda; Maya Arango, Juan (BENTHAM SCIENCE PUBL LTD., 2005-06)
      In order to gain inside the mechanism of action of a series of benzo[1,2-c]1,2,5-oxadiazole N-oxide derivatives with in vitro anti-trypanosomal activity, electrochemical and biological studies were performed. Cyclic ...
    • Agüero, Fernán; Repetto Scaramelli, Yolanda; Hellman, Ulf; Cazzulo, Juan José (1995)
    • Tapia, Ricardo A.; Prieto, Yolanda; Zamora, Gaston; Morello Casté, Antonio; Repetto Scaramelli, Yolanda (Freund Publishing House Ltd, 2000)
      A straightforward synthesis of a group of 4-alkylamino-6-nitroquinolines starting from a common intermediate, 5,8-dimethoxy-6-nitro-4(1H)quinolone 3, is described. These compounds were tested in vitro as potential ...
    • Tapia, Ricardo A.; Carrasco, Claudia; Ojeda, Scarlet; Salas, Cristian; Valderrama, Jaime A.; Morello Casté, Antonio; Repetto Scaramelli, Yolanda (2002)
      The synthesis of new indazol-4,7-dione derivatives via 1,3-dipolar cycloaddition of diazomethane with 2,3-dimethyl-1,4-benzoquinone (2) and 1,4-naphthoquinone (7) followed by N-alkylation of the pyrazol nitrogen atom of ...
    • Letelier, M. E.; Rodriguez, E.; Wallace, A.; Lorca, M.; Repetto Scaramelli, Yolanda; Morello Casté, Antonio; Aldunate, J. (1990)
      The following phenolic antioxidant food additives were evaluated against Trypanosoma cruzi epimastigotes: BHT, BHA, gallic acid and its methyl, propyl, octyl, and lauryl esters, 2,4-di-tert-butyl-6-(4-methoxybenzyl)-phenol, ...
    • Maya Arango, Juan; Bollo Dragnic, Soledad; Núñez Vergara, Luis; Squella Serrano, Juan; Repetto Scaramelli, Yolanda; Morello Casté, Antonio; Perie, J.; Chauviere, G. (PERGAMON-ELSEVIER SCIENCE, 2003-03-15)
      With the aim of determining the actual target(s) of nitro-group bearing compounds considered as possible leads for the development of drugs against Chagas' disease, we studied in parallel nitrofurans and nitroimidazoles. ...
    • Spadafora, Carmenza; Repetto Scaramelli, Yolanda; Torres, Cristina; Pino, Laura; Robello, Carlos; Morello Casté, Antonio; Gamarro, Francisco; Castanys, Santiago (2002)
      The cDNAs for two casein kinase 1 (CK1) homologues, TcCK1.1 and TcCK1.2, have been isolated from Trypanosoma cruzi. Both isoforms showed strong identity with other known CK1s. Their corresponding genes encode proteins of ...