Browsing by Author "XX641759"
Now showing items 1-13 of 13
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Rojas Zúñiga, Gabriel Ignacio (2015)El carcinoma oral de células escamosas (COCE) es la neoplasia maligna más frecuente en cavidad oral. La literatura señala un posible rol etiológico del virus papiloma humano (VPH) en cánceres ...
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Meneses Aguilera, Sebastián Eduardo (Universidad de Chile, 2015)El carcinoma oral de células escamosas (COCE) es la neoplasia maligna más frecuente de cavidad oral. La presentación de COCE en individuos sin los factores de riesgo más fuertemente asociados, como el tabaquismo y consumo ...
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Reyes Rojas, Montserrat (Universidad de Chile, 2014)El virus papiloma humano (VPH), es el agente causal de cánceres de la región anogenital. Hasta la fecha se ha encontrado asociación entre la presencia del VPH y el desarrollo de un subconjunto de cánceres de la región ...
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Riquelme Díaz, Luis Alberto (Universidad de Chile, 2015)Introducción: El carcinoma de células escamosas en la zona de cabeza y cuello es la neoplasia más prevalente, representando aproximadamente el 90% de los casos. La hipótesis de que existe una relación entre el cáncer y ...
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Reyes Rojas, Montserrat; Rojas Alcayaga, Gonzalo; Pennacchiotti Vidal, Gina; Carrillo, Diego; Muñoz, Juan P.; Peña, Nelson; Montes, Rodrigo; Lobos Jaimes-Freyre, Nelson; Aguayo, Francisco (Elsevier, 2015)Human papillomavirus (HPV) is the causal agent of cervical, anogenital and a subset of oropharyngeal carcinomas. In addition, the role of HPV in oral carcinogenesis has been suggested, although the findings are inconclusive. ...
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González Bergas, Fermín; Ortiz, Carolina; Reyes Rojas, Montserrat; Dutzan Muñoz, Nicolás; Patel, Vyomesh; Pereda, Cristián; Gleisner Muñoz, María Alejandra; López Nitsche, Mercedes; Gutkind, J. Silvio; Salazar Onfray, Flavio (John Wiley & Sons Ltd,, 2014)We have previously reported a novel method for the production of tumour-antigen-presenting cells (referred to as TAPCells) that are currently being used in cancer therapy, using an allogeneic melanomaderived cell lysate ...
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Reyes Rojas, Montserrat; Peña Oyarzún, Daniel; Silva, Patricio; Venegas, Sebastián; Criollo Céspedes, Alfredo; Torres Gómez, Vicente (Wiley, 2020)Potentially malignant lesions, commonly referred to as dysplasia, are associated with malignant transformation by mechanisms that remain unclear. We recently reported that increased Wnt secretion promotes the nuclear ...
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Reyes Rojas, Montserrat; Peña Oyarzún, Daniel; Maturana Ramírez, Andrea; Torres Gómez, Vicente (Elsevier, 2019)Objectives: To evaluate the localization of β-catenin in oral dysplastic cells, the expression of target genes upregulated in oral dysplasia, and the role of Wnt ligands in these events. Materials and methods: Subcellular ...
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Peña Oyarzún, Daniel; Rodríguez Peña, Marcelo; Burgos Bravo, Francesca; Vergara, Ángelo; Kretschmar Montecinos, Catalina; Sotomayor Flores, Cristián; Ramírez Sarmiento, César A.; De Smedt, Humbert; Reyes Rojas, Montserrat; Pérez, William; Torres Gómez, Vicente; Morselli, Eugenia; Altamirano, Francisco; Wilson, Christian; Hill, Joseph A.; Lavandero González, Sergio; Criollo Céspedes, Alfredo (Taylor & Francis, 2020)Macroautophagy/autophagy is an intracellular process involved in the breakdown of macromolecules and organelles. Recent studies have shown that PKD2/PC2/TRPP2 (polycystin 2, transient receptor potential cation channel), a ...
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Bernhard Malbrich, María Teresa (Universidad de Chile, 2014)Introducción: La hipersensibilidad dentinaria es el efecto adverso más frecuente en los tratamientos de blanqueamiento dental. Este fenómeno depende de la concentración del agente blanqueador y del tiempo de aplicación, ...
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Peña Oyarzún, Daniel; Reyes Rojas, Montserrat; Hernández Cáceres, María Paz; Kretschmar, Catalina; Morselli, Eugenia; Ramírez Sarmiento, César; Lavandero González, Sergio; Torres Gómez, Vicente; Criollo, Alfredo (Frontiers Media, 2020)Oral squamous cell carcinoma, the most common type of oral cancer, affects more than 275,000 people per year worldwide. Oral squamous cell carcinoma is very aggressive, as most patients die after 3 to 5 years post-diagnosis. ...
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Rivas, Solange; Silva, Patricio; Reyes Rojas, Montserrat; Sepúlveda, Hugo; Solano, Luis; Acuña, Juan; Guerrero, Marisol; Varas Godoy, Manuel; Quest, Andrew F. G.; Montecino, Martín; Torres Gómez, Vicente (Nature, 2020)Tumor hypoxia and the hypoxia inducible factor-1, HIF-1, play critical roles in cancer progression and metastasis. We previously showed that hypoxia activates the endosomal GTPase Rab5, leading to tumor cell migration and ...
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Reyes Rojas, Montserrat; Flores Lillo, Tania; Betancur, Diego; Peña Oyarzún, Daniel; Torres Gómez, Vicente (MDPI, 2020)Oral carcinogenesis is a complex and multifactorial process that involves cumulative genetic and molecular alterations, leading to uncontrolled cell proliferation, impaired DNA repair and defective cell death. At the ...