Browsing by Author "XX669162"
Now showing items 1-20 of 94
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(Informa Healthcare, 1991)1. 2,2'Azo-bis-amidinopropane (ABAP) thermal decomposition produces free radicals that initiate the lipid peroxidation of erythrocyte ghost membranes. 2. Addition of 6-n-propyl-2-thiouracil decreases the rate of the process, ...
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(1993)The effect of daily doses of 0.1 mg 3,3',5-triiodothyronine (T3) kg for three consecutive days on hepatic O2 uptake was studied in the isolated perfused rat liver, in the absence and presence of the antioxidants desferrioxamine ...
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(Royal Society Chemistry, 2017)Liver preconditioning by a docosahexaenoic acid (DHA) and triiodothyronine (T-3) combined protocol underlies peroxisome-proliferator activated receptor alpha (PPAR alpha)-fibroblast growth factor 21 (FGF21) upregulation, ...
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(ELSEVIER, 2006-05-01)Recently, we reported that 3,3,5-triiodothyronine (T-3) induces the expression of redox-sensitive genes as a nongenomic mechanism of T3 action. In this study, we show that T3 administration to rats (daily doses of 0. 1 ...
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(1982)Data reviewed here indicate that acute and chronic ethanol ingestion induce a decrease in the concentration of GSH and an increase in lipoperoxidation in the liver both in experimental animals and in man, changes that are ...
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(Royal Society of Chemistry, 2018)© The Royal Society of Chemistry. Ischemia-reperfusion (IR) is a deleterious condition associated with liver transplantation or resection that involves pro-oxidant and pro-inflammatory mechanisms. Considering that Rosa ...
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(Royal Soc Chemistry, 2016)Non-alcoholic fatty liver disease (NAFLD) is characterized by liver steatosis, oxidative stress, and drastic depletion of n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA), namely, eicosapentaenoic acid (C20:5 n-3, ...
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(Pergamon Press, 1990-11-30)Boldine, in low micromolar concentrations, was able to prevent brain bomogenate autooxidatíon, the 2,2'·uobis(2·amidinopropane)(AAP)·induced Iipid peroxidation of red cell plasma rnembranes, and the AAP·induced inactivation ...
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(1996)Aerobic life is characterized by a steady generation of reactive oxygen species balanced by a similar rate of their consumption by antioxidants. To maintain homeostasis, there is a requirement for the continuous regeneration ...
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(1994)Oxidative stress-related parameters in rat brain and liver were evaluated following acute (60 mg/kg i.p., 2 and 24 h after dosing) or short-term (1000 ppm in the diet for 90 days) lindane administration. Both treatments ...
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(Universidad de Chile, 2013)Nrf2 es un factor de transcripción que estimula la expresión de genes citoprotectores frente al estrés oxidativo (EOX). En condiciones homeostáticas Nrf2 está en el citoplasma formando un complejo con su inhibidor Keap1. ...
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(ELSEVIER, 2008-05-01)Hepatic ischemia-reperfusion (R) injury, a major clinical drawback during surgery, is abolished by L-3,3',5-triiodothyronine (T-3) administration. Considering that the triggering mechanisms are unknown, the aim of this ...
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Causal role of oxidative stress in unfolded protein response development in the hyperthyroid state (Elsevier, 2015)L-3,3',5-Triiodothyronine (T-3) induced liver oxidative stress underlies significant protein oxidation, which may trigger the unfolded protein response (UPR). Administration of daily doses of 0.1 mg T-3 for three consecutive ...
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(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2005-08)Iron is an essential micronutrient promoting oxidative stress in the liver of overloaded animals and human, which may trigger the expression of redox-sensitive genes. We have tested the hypothesis that chronic iron overload ...
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(Elsevier, 2018-06)Normal liver function includes a number of metabolic processes, secretion of cellular mediators and its role in immunobiology; these require a high energy supply, which is further enhanced under adverse conditions triggering ...
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(1997)1. Twenty-four hours after lindane exposure (5-60 mg/kg) a dose-dependent increase in the serum and hepatic levels of the insecticide was observed. Both the basal rate of O2 consumption and the sinusoidal efflux of lactate ...
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(2005)Cu is an essential trace element capable of producing toxic effects in animals and man when ingested acutely or chronically in excess. Although chronic Cu exposure is increasingly recognized as a public health issue, its ...
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(1985)Data presented here indicate that iron exposure exacerbates the changes in the glutathione status of the liver cell and the lipid peroxidative response of the tissue induced by acute ethanol intoxication. In these conditions, ...
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(Informa Healthcare, 1991)1. Lindane administered to untreated rats or rats pretreated with phenobarbital (PB) or 3-methylcholanthrene (MC) increased liver lipid peroxidation, of the same magnitude in all groups. 2. PB pretreatment produced a 50% ...
