Browsing by Author "XX673163"
Now showing items 1-9 of 9
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Herrera, Andrea; Muñoz Tapia, Patricia; Paris Pizarro, Irmgard; Díaz Véliz, Gabriela; Mora Gutiérrez, Sergio; Inzunza, José; Hultenby, Kjell; Cárdenas Matus, Julio; Jaña Prado, Fabián; Raisman Vozari, Rita; Gysling, Katia; Abarca, Jorge; Steinbusch, Harry; Segura Aguilar, Juan (Springer, 2016)L-Dopa continues to be the gold drug in Parkinson's disease ( PD) treatment from 1967. The failure to translate successful results from preclinical to clinical studies can be explained by the use of preclinical models which ...
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Schmeda Hirschmann, Guillermo; Quispe, Cristina; Vargas-Arana, Gabriel; Theoduloz, Cristina; Urra Faúndez, Felix; Cárdenas Matus, Julio (Pergamon-Elsevier Science, 2016)Little is known on the composition of Peruvian Amazon toad venoms. The large toad Rhinella marina is common in the cleared tropical forests of the Iquitos region and is regarded as poisonous. The venom from two different ...
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Estrada Hormazábal, Manuel; Cárdenas Matus, Julio; Liberona Leppe, José; Carrasco, María Angélica; Mignery, Gregory A.; Allen, Paul D.; Jaimovich Pérez, Enrique (Amer Soc Biochemistry Molecular Biology, 2001)Potassium depolarization of skeletal myotubes evokes slow calcium waves that are unrelated to contraction and involve the cell nucleus (Jaimovich, E., Reyes, R., Liberona, J. L., and Powell, J. A. (2000) Am. J. Physiol. ...
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Araya, Roberto; Liberona Leppe, José; Cárdenas Matus, Julio; Riveros Keller, Nora; Estrada Hormazábal, Manuel; Powell, Jeanne A.; Carrasco, María Angélica; Jaimovich Pérez, Enrique (Rockefeller University Press, 2003)The dihydropyridine receptor (DHPR), normally a voltage-dependent calcium channel, functions in skeletal muscle essentially as a voltage sensor, triggering intracellular calcium release for excitation-contraction coupling. ...
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Bustos, Galdo; Cruz, Pablo; Lovy, Alenka; Cárdenas Matus, Julio (Frontiers media SA, 2017)Cancer is characterized by an uncontrolled cell proliferation rate even under low nutrient availability, which is sustained by a metabolic reprograming now recognized as a hallmark of cancer. Warburg was the first to ...
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Smith Cortínez, Natalia Francisca (Universidad de Chile, 2015)La mitocondria y el retículo endoplasmático (ER) se encuentran física y funcionalmente acoplados. Los receptores de inositol 1,4,5-trifosfato (IP3R) son los principales canales de Ca2+ responsables de la liberación de ...
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Jana, F.; Cruz, P.; Bustos, G.; Urra, F.; Basualto Alarcón, Carla; Rios, M.; Madesh, M.; Cárdenas Matus, Julio (American Society Cell Biology, 2017)
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Liberona Leppe, José; Cárdenas Matus, Julio; Reyes, Roberto; Hidalgo Tapia, Jorge; Molgó, Jordi; Jaimovich Pérez, Enrique (CHURCHILL LIVINGSTONE, 2008-09)Brevetoxin-3 (PbTx-3), described to increase the open probability of voltage-dependent sodium channels, caused trains of action potentials and fast oscillatory changes in fluorescence intensity of fluo-3-loaded rat skeletal ...
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Miller, Russell A.; Shi, Yuji; Lu, Wenyun; Pirman, David A.; Jatkar, Aditi; Blatnik, Matthew; Wu, Hong; Cárdenas Matus, Julio; Wan, Min; Foskett, J. Kevin; Park, Junyoung O.; Zhang, Yiyi; Holland, William L.; Rabinowitz, Joshua D.; Birnbaum, Morris J. (Nature Publishing Group, 2018)Glucagon levels increase under homeostatic, fasting conditions, promoting the release of glucose from the liver by accelerating the breakdown of glycogen (also known as glycogenolysis). Glucagon also enhances gluconeogenic ...