Browsing by Author "XX676280"

Now showing items 41-60 of 81

    • Growth hormone (GH) responses to GH-releasing peptide and to GH-releasing hormone in GH-deficient children 
      Mericq, Verónica; Cassorla Goluboff, Fernando; Garcia, Hernan; Avila, Alejandra; Bowers, Cyril Y.; Merriam, George R. (1995)
      The GH-releasing peptides (GHRPs) are a family of hexa- and heptapeptides that specifically stimulate GH secretion in normal adults and children. They would be an attractive potential form of therapy for GH deficiency (GHD) ...
    • Growth hormone and treatment outcomes: Expert review of current clinical practice 
      Cassorla Goluboff, Fernando; Cianfarani, Stefano; Haverkamp, Fritz; Labarta, Jose I.; Loche, Sandro; Luo, Xiaoping; Maghnie, Mohamad; Mericq, Verónica; Muzsnai, Agota; Norgren, Svante; Ojaniemi, Marja; Pribilincova, Zuzana; Quinteiro, Sofia; Savendahl, Lars; Spinola E Castro, A (2011)
      Although there are guidelines for treatment of short stature, open questions regarding optimal management of growth hormone therapy still exist. Experts attending six international meetings agree that successful therapy ...
    • Growth hormone signaling in fibroblasts from newborn boys and prepubertal boys 
      Ocaranza Osses, Paula; Morales, Fernanda; Matamala, Álvaro; Gaete, Ximena; Román, Rossana; Lammoglia, Juan Javier; Cassorla Goluboff, Fernando (Elsevier, 2016-04)
      Background/aim: Responsiveness to GH in target cells is mediated by its receptor, which activates the Janus kinase-2 (JAK2) and STAT5 (signal transducers and activators of transcription 5) leading to the expression of IGF-1 ...
    • Heavy prenatal alcohol exposure and risk of stillbirth and preterm delivery 
      Cornman-Homonoff, Joshua; Kuehn, Devon; Aros, Sofia; Carter, Tonia C.; Conley, Mary R.; Troendle, James; Cassorla Goluboff, Fernando; Mills, James L. (2012)
      We prospectively identified 96 women consuming at least 4 drinks/day during pregnancy by screening 9628 pregnant women. In these women with heavy prenatal alcohol use, there were three stillbirths and one preterm delivery; ...
    • Hipopituitarismo congénito: Experiencia en 23 casos 
      Lammoglia, Juan Javier; Eyzaguirre, Francisca; Unanue Morales, Nancy; Román, Rossana; Codner Dujovne, Ethel; Cassorla Goluboff, Fernando; Mericq, Verónica (SOC MEDICA SANTIAGO, 2008-08)
      Background: Congenital hypopituitarism is an uncommon cause of hypophyseal insufficiency. It is less common than growth hormone deficiency, which has an incidence of 1:4.000 to 1:8.000 live newborns. Early diagnosis of ...
    • Hyperandrogenism in Adolescent Girls: Relationship with the Somatotrophic Axis 
      Hernández Cárdenas, María Isabel; Gaete Vásquez, Ximena; López Cuevas, Patricia; Villarroel Quintana, Claudio; Cavada Chacón, Gabriel; Ávila Alarcón, Rebeca; Iñíguez Vila, Germán; Cassorla Goluboff, Fernando (Karger, 2016)
    • IGF-IR/ERK content and response to IGF-I and insulin in adipocytes from small for gestational age children 
      Iñíguez Vila, Germán; Ormazábal Leiva, Paulina Fernanda; López, Teresa; Maldonado, Diego; Avila, Alejandra; Román, Rossana; Cassorla Goluboff, Fernando (2009)
      Background/Aims: The GH-IGF-I axis plays an important role on pre/postnatal growth in humans, and IGF-I regulates cell proliferation, differentiation, and metabolic homeostasis. The adipose tissue has an important function ...
    • Increased Anti-Müllerian Hormone Serum Concentrations in Prepubertal Daughters of Women with Polycystic ... 
      Sir Petermann, Lidia; Codner Dujovne, Ethel; Maliqueo Yevilao, Manuel; Echiburú López, Bárbara; Hitchsfeld, Catalina; Crisosto King, Nicolás; Pérez Bravo, Francisco; Recabarren, Sergio E.; Cassorla Goluboff, Fernando (Oxford Press, 2006-10)
      CONTEXT: Anti-Müllerian hormone (AMH) is produced by the granulosa cells and reflects follicular development. Adult women with polycystic ovary syndrome (PCOS) have increased levels of AMH associated with an excessive ...
    • Increased anti-müllerian hormone serum concentrations in prepubertal daughters of women with polycystic ... 
      Sir Petermann, Teresa; Codner Dujovne, Ethel; Maliqueo Yevilao, Manuel; Echiburú López, Bárbara; Hitschfeld, Catalina; Crisosto King, Nicolás; Pérez Bravo, Francisco; Recabarren, Sergio E.; Cassorla Goluboff, Fernando (Endocrine Society, 2006)
      Context: Anti-Müllerian hormone (AMH) is produced by the granulosa cells and reflects follicular development. Adult women with polycystic ovary syndrome (PCOS) have increased levels of AMH associated with an excessive ...
    • Insulinoma, presentación y evolución de dos casos clínicos 
      Lammoglia H., Juan Javier; Hernández C., María Isabel; Unanue Morales, Nancy; Román R., Rossana; Villanueva B., Jorge; Avila A., Alejandra; Mericq, Verónica; Codner Dujovne, Ethel; Cassorla Goluboff, Fernando (2008)
      Insulinoma is a very uncommon tumor in children, with an incidence in adults of 2 per million inhabitants.Clinical manifestations include neuroglycopenic or autonomic manifestations due to hypoglycemia. Wedescribe 2 pediatric ...
    • Low Concentrations of Estradiol and High Concentrations of Testosterone Increase JAK2 Phosphorylation in a ... 
      Ocaranza Osses, Paula; Iñíguez Vila, Germán; Cassorla Goluboff, Fernando (Karger, 2016)
    • Lower Antimullerian Hormone Levels (AMH) in Postmenarcheal Adolescents Conceived after Assisted Reproductive ... 
      Merino Osorio, Paulina; Pastene, C.; Salinas, A.; López P., Sandra; Jesam Gaete, Cristian; Villarroel Quintana, Claudio; Céspedes Pino, Pablo; Cassorla Goluboff, Fernando; Codner Dujovne, Ethel (Karger, 2015)
    • MC albright syndrome: clinical, hormonal and molecular studies 
      Soto, Julio C.; Cassorla Goluboff, Fernando; Hernández Cárdenas, María Isabel (Karger, 2017)
    • Menstrual Cycle and Ovarian Function in Young Adolescents Conceived after Assisted Reproductive Techniques (AcART) 
      Merino Osorio, Paulina; Pastene, C.; Salinas Quero, Soledad; López Cuevas, Patricia; Céspedes Pino, Pablo; Cassorla Goluboff, Fernando; Codner Dujovne, Ethel (Karger, 2016)
    • Metabolic and reproductive features before and during puberty in daughters of women with polycystic ovary syndrome 
      Sir Petermann, Teresa; Codner Dujovne, Ethel; Pérez, Virginia; Echiburú López, Bárbara; Maliqueo Yevilao, Manuel; Ladrón de Guevara, Amanda; Preisler, Jessica; Crisosto King, Nicolás; Sánchez, Fernando; Cassorla Goluboff, Fernando; Bhasin, Shalender (Endocrine Society, 2009)
      Context: A significant proportion of the first-degree female relatives of women with polycystic ovary syndrome (PCOS) may be at risk for developing PCOS. However, it is not known at which stage of pubertal development the ...
    • Metabolic profile in sons of women with polycystic ovary syndrome 
      Recabarren, Sergio E.; Smith, Rosita; Rios, Rafael; Maliqueo Yevilao, Manuel; Echiburú López, Bárbara; Codner Dujovne, Ethel; Cassorla Goluboff, Fernando; Rojas, Pedro; Sir Petermann, Teresa (Endocrine Society, 2008)
      Context: Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disorder with strong familial aggregation. It has been demonstrated that parents and brothers of PCOS women exhibit insulin resistance and related ...
    • Molecular characterization of Chilean patients with a clinical diagnosis of Noonan syndrome 
      Rodríguez, Fernando A.; Unanue Morales, Nancy; Hernández Cárdenas, María Isabel; Heath, Karen E.; Cassorla Goluboff, Fernando (De Gruyter, 2014)
      Background: Noonan syndrome (NS) is an autosomal dominant syndrome characterized by typical dysmorphic features, cardiac anomalies as well as postnatal growth retardation, and is associated with Ras-MAPK pathway gene ...
    • Molecular study of RAS/ MAPK pathway genes in patients with cryptorchidism 
      Rodríguez, Fernando Adrián; Vallejos, Carla; Unanue, Nancy; Hernández Cárdenas, María Isabel; Celis Lagos, María Soledad; Martin Arenas, Rubén; Palomares Bralo, María; Heath, Karen E.; López Castillo, María Teresa; Cassorla Goluboff, Fernando (Karger, 2017)
    • Molecular Study of Rasopathies in Patients with Isolated Cryptorchidism 
      Rodríguez, Fernando A.; Vallejo, C.; Pastrián, M.; Poblete, D.; Unanue Morales, Nancy; Hernández, I.; Celis, S.; Arenas, R.; Palomares, M.; Heath, K.; López, M.; Cassorla Goluboff, Fernando (Karger, 2015)
    • Oestrogen activity of the serum in adolescents with Type 1 diabetes 
      Martínez, D.; Castro, A.; Merino Osorio, Paulina; López, P.; Lardone, María Cecilia; Iñíguez Vila, Germán; Cassorla Goluboff, Fernando; Codner Dujovne, Ethel (2016)
      AimsTo assess serum oestrogen levels and oestrogenic activity in adolescents with Type 1 diabetes compared with a healthy control group. MethodsWe conducted a cross-sectional study that evaluated adolescents with Type ...