Browsing by Author "XX676809"
Now showing items 1-12 of 12
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(Universidad de Chile, 2009)Las enfermedades causadas por los péptidos amiloides son numerosas y heterogéneas, afectan a una gran cantidad de órganos y son de importancia tanto para el hombre como los animales. A pesar de que una característica común ...
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(2007)The CNh and CTb cell lines are derived from the cerebral cortex of normal and trisomy 16 mice, an animal model of human trisomy 21, Down syndrome (DS), and represent in vitro models to study cellular events associated with ...
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(Public Library Science, 2015)Glucose-stimulated insulin secretion (GSIS) from pancreatic beta-cells requires an increase in intracellular free Ca2+ concentration ([Ca2+]). Glucose uptake into beta-cells promotes Ca2+ influx and reactive oxygen species ...
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(Public Library of Science, 2015)© 2015, Public Library of Science. All rights reserved. This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for ...
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(ENDOCRINE SOC, 2010-10)Intracellular calcium levels ([Ca2+](i)) and glucose uptake are central to cardiomyocyte physiology, yet connections between them have not been studied. We investigated whether insulin regulates [Ca2+](i) in cultured ...
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(Universidad de Chile, 2008)La Diabetes Mellitus es una de las enfermedades crónicas no transmisibles más frecuentes del ser humano de cualquier edad. Se considera un problema de salud pública por su elevada morbilidad y mortalidad. La Diabetes ...
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(ELSEVIER, 2006-01)Incorporation of Alzheimer's disease amyloid beta-proteins (A beta Ps) across natural and artificial bilayer membranes leads to the formation of cation-selective channels. To study the peptide-membrane interactions involved ...
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(ELSEVIER, 2010)Islet transplantation is a potential cure for type 1 diabetes, but clinical results have been disappointing. Currently, islet isolation is by enzymatic digestion of the pancreas which has significant pitfalls: warm ...
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(2003)1 We have investigated the effects of loperamide on intracellular Ca2+ stores and membrane K+ channels in insulin-secreting hamster insulinoma (HIT-T15) cells. 2 In cell-attached patch-clamp mode, loperamide (3 – 250 mM) ...
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(SOCIEDAD BIOLGIA CHILE, 2006)We used the single-microelectrode voltage-clamp technique to record ionic currents from pancreatic beta-cells within intact mouse islets of Langerhans at 37 degrees C, the typical preparation for studies of glucose-induced ...
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(Society of Biology of Chile, 2006)We used the single-microelectrode voltage-clamp technique to record ionic currents from pancreatic β-cells within intact mouse islets of Langerhans at 37C, the typical preparation for studies of glucose-induced "bursting" ...
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(2012)Insulin secretion from the pancreatic β-cell is controlled by changes in membrane potential and intracellular Ca2+. The contribution of intracellular Ca2+ stores to this process is poorly understood. We have previously ...
