Browsing by Author "XX676972"

Now showing items 1-6 of 6

    • A synthetic peptide homologous to IL-10 functional domain induces monocyte differentiation to TGF-β+ ... 
      López, Mercedes N.; Pesce Reyes, Bárbara; Kurte, Mónica; Pérez Núñez, Claudio; Segal, Gabriela; Roa, Johanna; Aguillón Gutiérrez, Juan Carlos; Mendoza Naranjo, Ariadna; Gesser, Borbala; Larsen, Christian; Villablanca, Andrea; Choudhury, Aniruddha; Kiessling, Rolf; Salazar Onfray, Flavio (2011)
      We have previously demonstrated that IT9302, a nonameric peptide homologous to the C-terminal domain of human IL-10, mimics several effects of the cytokine including down-regulation of the antigen presentation machinery ...
    • Dexamethasone turns tumor antigen-presenting cells into tolerogenic dendritic cells with T cell inhibitory ... 
      Falcón Beas, Cristián; Tittarelli, Andrés; Mora-Bau, Gabriela; Tempio, Fabián; Pérez Núñez, Claudio; Hevia, Daniel; Behrens, Carolina; Flores, Iván; Falcón-Beas, Felipe; Garrido, Paola; Ascui, Gabriel; Pereda, Cristián; González, Fermín E.; Salazar Onfray, Flavio; López, Mer (Elsevier GmbH, 2019)
      Background: Dendritic cells (DCs) are usually immunogenic, but they are also capable of inducing tolerance under anti-inflammatory conditions. Immunotherapy based on autologous DCs loaded with an allogeneic melanoma cell ...
    • Pure platelet-rich plasma and supernatant of calcium-activated P-PRP induce different phenotypes of human ... 
      Escobar, Gisselle; Escobar Álvarez, Alejandro; Ascui, Gabriel; Tempio, Fabián I.; Ortiz, María C.; Pérez Núñez, Claudio; López, Mercedes N. (Future Medicine, 2018)
      Aim: This study aimed to evaluate the effect of two platelet preparations used in the clinic, pure platelet-rich plasma (P-PRP) and the supernatant of calcium-activated P-PRP (S-PRP), on the phenotype of human macrophages. ...
    • Respuesta inmune contra antígenos menores de histocompatibilidad en el trasplante alogénico de progenitores ... 
      Rabanales T., Ramón; Larrondo Lillo, Milton; Alfaro Lucero, Jorge; Pérez Núñez, Claudio (Hospital Clínico Universidad de Chile, 2010)
      Patients who receive allo hematopoietic stem cell transplantation (SCT) could develop graft versus host disease and/or graft versus tumour effect. These immunological responses can happen even with perfect fully HLA matched ...
    • T-kininogen induces endothelial cell proliferation 
      Pérez, Viviana; Leiva Salcedo, Elías; Acuña Castillo, Claudio; Aravena, Mauricio; Gómez, Christian; Sabaj Diez, Valeria; Colombo, Alicia; Nishimura, Sumiyo; Pérez Núñez, Claudio; Walter, Robin Ann; Sierra, Felipe (ELSEVIER, 2006-03)
      Basal proliferation of endothelial cells increases with age, and this might play a role in the etiology of age-related vascular diseases, as well as angiogenesis. Serum kininogen levels increase during aging in rats and ...
    • The role of regulatory T lymphocytes in the induced immune response mediated by biological vaccines 
      López, Mercedes; Aguilera, Raquel; Pérez Núñez, Claudio; Mendoza Naranjo, Ariadna; Pereda, Cristian; Ramirez, Marcos; Ferrada, Carlos; Aguillón Gutiérrez, Juan Carlos; Salazar Onfray, Flavio (Elsevier GmbH, 2006)
      Immunotherapy has become a novel therapeutic alternative for various kinds of tumours. Recently, we have finalized the first phase I clinical study in Chile for the treatment of advanced malignant melanoma, using dendritic ...