Browsing by Author "XX677307"

Now showing items 1-4 of 4

    • Diminished Acute Phase Response and Increased Hepatic Inflammation of Aged Rats in Response to Intraperitoneal ... 
      Gómez, Christian; Acuña Castillo, Claudio; Pérez Núñez, Claudio; Leiva Salcedo, Elías; Riquelme, Denise; Ordenes, Gamaliel; Oshima, Kiyoko; Aravena, Mauricio; Pérez, Viviana I.; Nishimura, Sumiyo; Sabaj Diez, Valeria; Walter, Robin Ann; Sierra, Felipe (GERONTOLOGICAL SOC AMER, 2008-12)
      Aging is associated with a deterioration of the acute phase response to inflammatory challenges. However, the nature of these defects remains poorly defined. We analyzed the hepatic inflammatory response after intraperitoneal ...
    • Serum from aged F344 rats conditions the activation of young macrophages 
      Gómez, Christian; Acuña Castillo, Claudio; Nishimura, Sumiyo; Pérez, Viviana; Escobar, Alejandro; Salazar Onfray, Flavio; Sabaj Diez, Valeria; Torres, Claudio; Walter, Robin Ann; Sierra, Felipe (ELSEVIER, 2006-03)
      There is considerable controversy about the molecular mechanisms responsible for the variations in innate immunity associated with age. While in vivo, aged animals and humans react to an inflammatory signal with ail excessive ...
    • T-kininogen induces endothelial cell proliferation 
      Pérez, Viviana; Leiva Salcedo, Elías; Acuña Castillo, Claudio; Aravena, Mauricio; Gómez, Christian; Sabaj Diez, Valeria; Colombo, Alicia; Nishimura, Sumiyo; Pérez Núñez, Claudio; Walter, Robin Ann; Sierra, Felipe (ELSEVIER, 2006-03)
      Basal proliferation of endothelial cells increases with age, and this might play a role in the etiology of age-related vascular diseases, as well as angiogenesis. Serum kininogen levels increase during aging in rats and ...
    • T-kininogen, a cystatin-like molecule, inhibits ERK-dependent lymphocyte proliferation 
      Acuña Castillo, Claudio; Aravena, Mauricio; Leiva Salcedo, Elías; Pérez, Viviana; Gómez, Christian; Sabaj Diez, Valeria; Nishimura, Sumiyo; Pérez Núñez, Claudio; Colombo, Alicia; Walter, Robin Ann; Sierra, Felipe (ELSEVIER, 2005-12)
      Plasma levels of kininogens increase with age in both rats and humans. Kininogens are inhibitors of cysteine proteinases, and filarial cysteine proteinase inhibitors (cystatins) reduce the proliferation of T cells. We ...