Browsing by Author "cd2f48e3-516e-4658-a73a-952a9b58ae6c"

Now showing items 1-9 of 9

    • ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans 
      Boekstegers, Félix; Marcelain Cubillos, Katherine; Barahona Ponce, Carol; Báez Benavides, Pablo F.; Müller, Bettina; Toro, Gonzalo de; Retamales, Javier; Barajas Barajas, Olga; Ahumada Olea, Mónica; Morales, Erik; Rojas, Armando; Sanhueza, Verónica; Loader, Denisse; Rivera, María Teresa; Gutiérrez, Lorena; Bernal, Giuliano; Ortega, Alejandro; Montalvo, Domingo; Portiño, Sergio; Bertrán, María Enriqueta; Gabler, Fernando; Spencer, Loreto; Olloquequi, Jordi; González Silos, Rosa; Fischer, Christine; Scherer, Dominique; Jenab, Mazda; Aleksandrova, Krasimira; Katzke, Verena; Weiderpass, Elisabete; Moradi, Tahereh; Fischer, Krista; Bossers, Willem; Brenner, Hermann; Hveem, Kristian; Eklund, Niina; Völker, Uwe; Waldenberger, Melanie; Fuentes Guajardo, Macarena; González-José, Rolando; Bedoya, Gabriel; Bortolini, María C.; Canizales, Samuel; Gallo, Carla; Ruiz Linares, Andrés; Rothhammer, Francisco; Bermejo, Justo Lorenzo (Elsevier, 2020)
      Background: The first large-scale genome-wide association study of gallbladder cancer (GBC) recently identified and validated three susceptibility variants in the ABCB1 and ABCB4 genes for individuals of Indian descent. ...
    • Acute and subchronic toxicological study of senna in rodents Toxicología aguda y subcrónica de una pasta ... 
      Hancke, Juan; Cáceres, Dante; Burgos, Rafael A.; Hernández, Doris; Rojas, Armando; Morales, Miguel A. (2009)
      Senna crude herbal paste, CIRUELAX®, laxative used in America and Spain, was administered by oral gavage to mice and rats once daily in doses from 2 to 10 g/kg for 7 days. LD50 was rated as higher than 10 g/kg. To determine ...
    • Advanced glycation and ROS: A link between diabetes and heart failure 
      Rojas, Armando; Mercadal, Enrique; Figueroa, Hector; Morales, Miguel A. (2008)
      Despite many advances achieved to date, heart failure (HF) remains a leading cause of morbidity and mortality. There is a widely-accepted consensus that HF and diabetes are strongly linked by at least 3 mechanisms: associated ...
    • Facing up the ROS labyrinth - Where to go? 
      Rojas, Armando; Figueroa, Hector; Morales, Miguel A.; Re, Lamberto (2006)
      Evidence indicates that oxidative stress refers to a condition where cells are subjected to excessive levels of reactive oxygen species (ROS). Overall vascular function is dependent upon a fine balance between oxidant and ...
    • Inhibition of RAGE axis signaling: A pharmacological challenge 
      Rojas, Armando; Morales, Miguel; Gonzalez, Ileana; Araya, Paulina (Bentham Science Publishers B.V., 2019)
      The Receptor for Advanced Glycation End Products (RAGE) is an important cell surface receptor, which belongs to the IgG super family and is now considered as a pattern recognition receptor. Because of its relevance in many ...
    • Is ozone pre-conditioning effect linked to Nrf2/EpRE activation pathway in vivo? A preliminary result 
      Re, Lamberto; Martínez Sánchez, Gregorio; Bordicchia, Marica; Malcangi, Giuseppe; Pocognoli, Antonella; Morales Segura, Miguel Ángel; Rothchild, John; Rojas, Armando (Elsevier, 2014)
      The present preliminary study has been focused on verifying whether ozone preconditioning may be linked to Nrf2/EpRE (nuclear factor erythroid 2/electrophile-responsive element) activation pathway in vivo. Healthy volunteers ...
    • Polyphenols and AGEs/RAGE axis. Trends and challenges 
      González, Ileana; Morales Segura, Miguel; Rojas, Armando (Elsevier, 2020)
      The formation of advanced glycation end-products (AGEs) is a key pathophysiological event linked not only to the onset and progression of diabetic complications, but also to neurodegeneration, cardiovascular diseases, ...
    • Receptor for advanced glycation end-products axis and coronavirus disease 2019 in inflammatory bowel diseases: ... 
      Rojas, Armando; Schneider, Iván; Lindner, Cristian; González, Ileana; Morales Segura, Miguel Ángel (Baishideng Publishing Group, 2021)
      Compelling evidence supports the crucial role of the receptor for advanced glycation end-products (RAGE) axis activation in many clinical entities. Since the beginning of the coronavirus disease 2019 pandemic, there is ...
    • SARS-CoV-2-mediated inflammatory response in lungs: should we look at RAGE? 
      Rojas, Armando; González, Ileana; Morales Segura, Miguel (Springer, 2020)
      The novel coronavirus disease (COVID-19) pandemic is placing significant strains on health systems, scientific communities, essential public services, and economies all over the world. In this context, the world ' s ...