SARS-CoV-2-mediated inflammatory response in lungs: should we look at RAGE?
Artículo
![Thumbnail](/themes/Mirage2/images/cubierta.jpg)
Open/ Download
Access note
Acceso Abierto
Publication date
2020Metadata
Show full item record
Cómo citar
Rojas, Armando
Cómo citar
SARS-CoV-2-mediated inflammatory response in lungs: should we look at RAGE?
Abstract
The novel coronavirus disease (COVID-19) pandemic is placing significant strains on health systems, scientific communities, essential public services, and economies all over the world. In this context, the world ' s scientific biomedical establishment is unleashing an unprecedented response to the COVID-19 pandemic. This is a battle against time, considering the thousands of human lives are lost every day. In this commentary, based on a very recent research report, we intend to highlight how a new mechanism describing the RAGE transactivation produced by Ang II-mediated ATR1 activation can run continuously and thus, reinforcing a sustained inflammation in lungs, due to the SARS-Cov-2-mediated imbalance of the ACE/And II/ATR1 pathway.
Indexation
Artículo de publicación ISI Artículo de publicación SCOPUS
Quote Item
Inflammation Research (Jul 2020) 69(7) : 641-643
Collections
The following license files are associated with this item: