Now showing items 1-13 of 13

    • Boekstegers, Félix; Marcelain Cubillos, Katherine; Barahona Ponce, Carol; Báez Benavides, Pablo F.; Müller, Bettina; Toro, Gonzalo de; Retamales, Javier; Barajas Barajas, Olga; Ahumada Olea, Mónica; Morales, Erik; Rojas, Armando; Sanhueza, Verónica; Loader, Denisse; Rivera, María Teresa; Gutiérrez, Lorena; Bernal, Giuliano; Ortega, Alejandro; Montalvo, Domingo; Portiño, Sergio; Bertrán, María Enriqueta; Gabler, Fernando; Spencer, Loreto; Olloquequi, Jordi; González Silos, Rosa; Fischer, Christine; Scherer, Dominique; Jenab, Mazda; Aleksandrova, Krasimira; Katzke, Verena; Weiderpass, Elisabete; Moradi, Tahereh; Fischer, Krista; Bossers, Willem; Brenner, Hermann; Hveem, Kristian; Eklund, Niina; Völker, Uwe; Waldenberger, Melanie; Fuentes Guajardo, Macarena; González-José, Rolando; Bedoya, Gabriel; Bortolini, María C.; Canizales, Samuel; Gallo, Carla; Ruiz Linares, Andrés; Rothhammer, Francisco; Bermejo, Justo Lorenzo (Elsevier, 2020)
      Background: The first large-scale genome-wide association study of gallbladder cancer (GBC) recently identified and validated three susceptibility variants in the ABCB1 and ABCB4 genes for individuals of Indian descent. ...
    • Sagredo, Eduardo A.; Sagredo, Alfredo I.; Blanco, Alejandro; Rojas De Santiago, Pamela; Rivas, Solange; Assar Cuevas, Rodrigo; Pérez, Paola; Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo (Elsevier, 2020)
      RNA editing has emerged as a novel mechanism in cancer progression. The double stranded RNA-specific adenosine deaminase (ADAR) modifies the expression of an important proportion of genes involved in cell cycle control, ...
    • Dagnino Subiabre, Alexies; Marcelain Cubillos, Katherine; Arriagada, Christian; Paris Pizarro, Irmgard; Caviedes Fernández, Pablo; Caviedes, R.; Segura Aguilar, Juan (2000)
      Angiotensin receptor II mRNA was found to be expressed in dopaminergic neuronal cell line RCSN3 of rat substantia nigra using RT-PCR reaction. Aminochrome (150 μM), a metabolite of the dopamine oxidative pathway, was found ...
    • Jain, J.; Moreno, J.; Andaur, R.; Armisen Yáñez, Ricardo; Morales D., Ignacio; Marcelain Cubillos, Katherine; Avaria, G.; Bora, B.; Davis, S.; Pavez, C.; Soto, L. (American Institute of Physics, 2017)
      Plasma focus devices may arise as useful source to perform experiments aimed to study the effects of pulsed radiation on human cells in vitro. In the present work, a table top hundred joules plasma focus device, namely ...
    • Signore Ahumada, Iskra; Jerez, Carolina; Figueroa, Diego; Suazo Sanhueza, José Lorenzo; Marcelain Cubillos, Katherine; Cerda Arancibia, Óscar; Colombo Flores, Alicia (Wiley, 2016)
      Background: Orofacial clefts (OFCs) are common birth defects, which include a range of disorders with a complex etiology affecting formation of craniofacial structures. Some forms of syndromic OFCs are produced by defects ...
    • Aracena, M.; Cares, C.; Arredondo, S.; Marcelain Cubillos, Katherine; González Hormazábal, Patricio (Wiley, 2018)
    • Urzúa Tobar, Ulises; Chacón, Carlos; Lizama, Luis; Sarmiento, Sebastián; Villalobos, Pía; Kroxato, Belén; Marcelain Cubillos, Katherine; González Burgos, María Julieta (International Society on Aging and Disease, 2017)
      Aging intersects with reproductive senescence in women by promoting a systemic low-grade chronic inflammation that predisposes women to several diseases including ovarian cancer (OC). OC risk at menopause is significantly ...
    • Obreque, Javiera; Vergara, Luis; Suárez, Felipe; García, Patricia; Marcelain Cubillos, Katherine; Toro, Jessica; Solange, Rivas; Rosa, Lorena; Roa, Juan Carlos; Nervi, Bruno; Viñuela, Eduardo; Aguayo, Gloria; Muniz Muñoz, Sabrina; Caire, Nicole; Escalante, Anrried; Mondaca, Sebastián; Nervi, Bruno (Lippincott Williams & Wilkins, 2020)
    • Scherer, Dominique; Dávila López, Marcela; Goeppert, Benjamín; Abrahamsson, Sanna; González Silos, Rosa; Nova, Igor; Marcelain Cubillos, Katherine; Roa, Juan C.; Ibberson, David; Umu, Sinan U.; Ballestad Rounge, Trine; Roessler, Stephanie; Bermejo, Justo Lorenzo (MDPI, 2020)
      Simple Summary Research on gallbladder cancer (GBC) has been largely neglected and molecular GBC data is underrepresented in public databases. Cancer cell lines constitute a valuable tool to examine the mechanisms of ...
    • Cappelli, Claudio; Sepúlveda, Hugo; Rivas Vera, Solange; Pola Véliz, Víctor; Urzúa Tobar, Ulises; Donoso Luna, Gerardo; Sagredo Campos, Eduardo; Carrero Zapata, David; Casanova Ortiz, Emmanuel; Sagredo Campos, Alfredo; González Vergara, Marisel; Manterola Zúñiga, Marcia; Nardocci, Gino; Armisén Yañez, Ricardo; Montecino, Martín; Marcelain Cubillos, Katherine (Elsevier, 2020)
      Several mechanisms directing a rapid transcriptional reactivation of genes immediately after mitosis have been described. However, little is known about the maintenance of repressive signals during mitosis. In this work, ...
    • Bermejo, Justo Lorenzo; Boekstegers, Félix; González Silos, Rosa; Marcelain Cubillos, Katherine; Báez Benavides, Pablo; Barahona Ponce, Carol; Mueller, Bettina; Ferreccio, Catterina; Koshiol, Jill; Fischer, Christine; Peil, Barbara; Sinsheimer, Janet; Fuentes Guajardo, Macarena; Barajas Barajas, Olga; González José, Rolando; Bedoya, Gabriel; Bortolini, María Catira; Canizales Quinteros, Samuel; Gallo, Carla; Ruiz Linares, Andrés; Rothhammer Engel, Francisco (Public Library Science, 2017)
      Latin Americans are highly heterogeneous regarding the type of Native American ancestry. Consideration of specific associations with common diseases may lead to substantial advances in unraveling of disease etiology and ...
    • Sagredo, Alfredo I.; Sagredo, Eduardo A.; Pola, Victor; Echeverría, César; Andaur, Rodrigo; Michea Acevedo, Luis; Stutzin Schottlander, Andrés; Simon, Felipe; Marcelain Cubillos, Katherine; Armisén, Ricardo (Wiley-Liss Inc., 2019)
      © 2018 Wiley Periodicals, Inc. Transient Receptor Potential Melastatin 4 (TRPM4) is a Ca 2+ -activated and voltage-dependent monovalent cation channel, which depolarizes the plasma cell membrane, thereby modulating Ca 2+ ...
    • Sagredo, A.; Sagredo, Eduardo A.; Cappelli, Claudio; Baez, Pablo; Andaur, Rodrigo E.; Blanco, Constanza; Tapia, Julio C.; Echeverría, César; Cerda, Oscar; Stutzin Schottlander, Andrés; Simon, Felipe; Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo (Febs Press Science Publishing by Scientist, 2018)
      Increased expression of the TRPM4 channel has been reported to be associated with the progression of prostate cancer. However, the molecular mechanism underlying its effect remains unknown. This work found that decreasing ...