Angiotensin receptor II is present in dopaminergic cell line of rat substantia nigra and it is down regulated by aminochrome

Dagnino Subiabre, Alexies; Marcelain Cubillos, Katherine; Arriagada, Christian; Paris Pizarro, Irmgard; Caviedes Fernández, Pablo; Caviedes, R.; Segura Aguilar, Juan

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2000

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Angiotensin receptor II is present in dopaminergic cell line of rat substantia nigra and it is down regulated by aminochromeFormato de cita

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Dagnino Subiabre, Alexies;
Marcelain Cubillos, Katherine;
Arriagada, Christian;
Paris Pizarro, Irmgard;
Caviedes Fernández, Pablo;
Caviedes, R.;
Segura Aguilar, Juan;

Abstract

Angiotensin receptor II mRNA was found to be expressed in dopaminergic neuronal cell line RCSN3 of rat substantia nigra using RT-PCR reaction. Aminochrome (150 μM), a metabolite of the dopamine oxidative pathway, was found to down regulate the expression of angiotensin receptor mRNA in RCSN3 cells by 83% (p < 0.05).

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URI: https://repositorio.uchile.cl/handle/2250/160125
ISSN: 03008177

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Molecular and Cellular Biochemistry 212: 131–134, 2000.

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