Angiotensin receptor II is present in dopaminergic cell line of rat substantia nigra and it is down regulated by aminochrome
Author
dc.contributor.author
Dagnino Subiabre, Alexies
Author
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Marcelain Cubillos, Katherine
Author
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Arriagada, Christian
Author
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Paris Pizarro, Irmgard
Author
dc.contributor.author
Caviedes Fernández, Pablo
Author
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Caviedes, R.
Author
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Segura Aguilar, Juan
Admission date
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2019-01-29T14:12:11Z
Available date
dc.date.available
2019-01-29T14:12:11Z
Publication date
dc.date.issued
2000
Cita de ítem
dc.identifier.citation
Molecular and Cellular Biochemistry 212: 131–134, 2000.
Identifier
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03008177
Identifier
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https://repositorio.uchile.cl/handle/2250/160125
Abstract
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Angiotensin receptor II mRNA was found to be expressed in dopaminergic neuronal cell line RCSN3 of rat substantia nigra using RT-PCR reaction. Aminochrome (150 μM), a metabolite of the dopamine oxidative pathway, was found to down regulate the expression of angiotensin receptor mRNA in RCSN3 cells by 83% (p < 0.05).