Now showing items 1-13 of 13

    • Aránguiz Urroz, Pablo Daniel; Contreras Ferrat, Ariel Eduardo; Rojas Rivera, Diego; Troncoso Cotal, Rodrigo Hernán; Marambio Morales, Paola Angélica; Toro, Bárbara; Sanhueza Muñoz, Carlos Joaquín; Pennanen Saavedra, Christian; Díaz Elizondo, Jessica; Parra Ortíz, María Valentina; Chiong Lay, Mario; Díaz Araya, Guillermo; Lavandero González, Sergio (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2006)
      Históricamente, la apoptosis y la necrosis han sido consideradas como las dos formas fundamentales de muerte celular. Sin embargo, evidencias recientes sugieren que la muerte celular programada no está confinada sólo a ...
    • Vivar, Raúl; Humeres, Claudio; Varela, Marcelo; Ayala, Pedro; Guzmán, Nancy; Olmedo, Ivonne; Catalán, Mabel; Boza Fuentes, Pía; Muñoz, Claudia; Díaz Araya, Guillermo (2012)
      Cardiac fibroblast (CF) death by ischemia/reperfusion (I/R) has major implications for cardiac wound healing. Although IGF-1 has well-known cytoprotective effects, no study has been done on CF subjected to simulated ...
    • Yévenes, Gonzalo E.; Bravo, Javier A.; Díaz Araya, Guillermo; Sotomayor Zárate, Ramón; Fiedler Temer, Jenny; Reyes Parada, Miguel; Fuentealba, Jorge (Frontiers Media, 2020)
    • Muñoz Rodríguez, Claudia Muriel; Fernández, Samuel; Osorio, Jose Miguel; Olivares, Francisco; Anfossi, Renatto; Bolivar, Samir; Humeres, Claudio; Boza Fuentes, Pía; Vivar, Raúl; Pardo Jiménez, Viviana Gladys; Hemmings, Karen E.; Turner, Neil A.; Díaz Araya, Guillermo (Elsevier, 2018-07-15)
      Cardiac fibroblasts (CF) are key cells for maintaining extracellular matrix (ECM) protein homeostasis in the heart, and for cardiac repair through CF-to-cardiac myofibroblast (CMF) differentiation. Additionally, CF play ...
    • Muñoz Rodríguez, Claudia Muriel; Fernández, Samuel; Osorio, José Miguel; Ritchie Olivares, Francisco Antonio; Anfossi, Renatto; Bolivar, Samir; Humeres, Claudio; Boza Fuentes, Pía; Vivar, Raúl; Pardo Jiménez, Viviana Gladys; Hemmings, Karen E.; Turner, Neil A.; Díaz Araya, Guillermo (Elsevier, 2018-07-15)
      Cardiac fibroblasts (CF) are key cells for maintaining extracellular matrix (ECM) protein homeostasis in the heart, and for cardiac repair through CF-to-cardiac myofibroblast (CMF) differentiation. Additionally, CF play ...
    • Boza Fuentes, Pía; Ayala, Pedro; Vivar Sánchez, Raúl; Humeres Martínez, Claudio; Tapia Cáceres, Felipe; Muñoz, Claudia; García Nannig, Lorena; Hermoso Ramello, Marcela; Díaz Araya, Guillermo (Elsevier, 2016)
      Cardiac inflammation can be produced by pathogen-associated molecular patterns (PAMPs), from parasitic, bacterial or viral origin; or by danger-associated molecular patterns (DAMPs), released from dead cells after cardiac ...
    • Klionsky, Daniel J.; Troncoso Cotal, Rodrigo; Chiong Lay, Mario; Díaz Araya, Guillermo; Glavic Maurer, Álvaro; Corbalán, Ramón; Matus, Soledad; Segura Aguilar, Juan; Hetz Flores, Claudio (Taylor & Francis inc., 2016)
    • Olivares Silva, Francisco Javier; Landaeta, Rodolfo; Aránguiz, Pablo; Bolivar, Samir; Humeres Martínez, Claudio; Anfossi, Renatto; Vivar Sánchez, Raúl; Boza Fuentes, Pía; Muñoz Jofré, Claudia; Pardo Jiménez, Viviana Gladys; Peiro, Concepción; Sánchez Ferrer, Carlos; Díaz Araya, Guillermo (Elsevier, 2018)
      Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and growth factors released in cardiac tissue in cardiac injury events, such as myocardial infarction (MI). Cardiac injury involves the ...
    • Contreras Ferrat, Ariel Eduardo; Aránguiz Urroz, Pablo Daniel; Díaz Elizondo, Jessica; Chiong Lay, Mario; Muñoz, Juan Pablo; Parra Ortíz, María Valentina; Ibarra, Cristián; Rojas Rivera, Diego; Troncoso Cotal, Rodrigo; Eisner, Verónica; Salas, Daniela; Rodríguez Villarroel, Andrea Elizabeth; Carrasco Alarcón, Loreto del Pilar; Díaz Araya, Guillermo; Lavandero González, Sergio (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2006)
      El factor de crecimiento análogo a insulina tipo 1 (IGF-1) es un péptido relacionado estructural y funcionalmente con insulina que posee efectos mitogénicos y citoprotectores. Sus efectos biológicos dependen de la activación ...
    • Núñez Vergara, Luis; Squella Serrano, Juan; Bollo Dragnic, Soledad; Marín Catalán, Rigoberto; Pino, L.; Díaz Araya, Guillermo; Letelier Muñoz, María Eugenia (PERGAMON-ELSEVIER SCIENCE LTD, 1998-01)
      1. Isradipine and lacidipine, two new drugs that are members of the nitro-aryl-1,4-dihydropyridine family, produced inhibition of both growth cultures and oxygen consumption on epimastigotes of Trypanosoma cruzi Tulahuen ...
    • Bolivar, Samir; Santana, Roxana; Ayala, Pedro; Landaeta, Rodolfo; Boza Fuentes, Pía; Humeres Martínez, Claudio; Vivar Sánchez, Raúl; Muñoz Jofré, Claudia; Pardo, Viviana; Fernández, Samuel; Anfossi, Renatto; Díaz Araya, Guillermo (Springer, 2017)
      Bacterial lipopolysaccharide (LPS) is a known ligand of Toll-like receptor 4 (TLR4) which is expressed in cardiac fibroblasts (CF). Differentiation of CF to cardiac myofibroblasts (CMF) is induced by transforming growth ...
    • Vivar Sánchez, Raúl; Humeres, Claudio; Anfossi, Renatto; Bolívar, Samir; Catalán Díaz, Mabel; Hill, Joseph; Lavandero González, Sergio; Díaz Araya, Guillermo (Elsevier, 2020)
      Cardiac fibroblasts (CFs) are necessary to maintain extracellular matrix (ECM) homeostasis in the heart. Normally, CFs are quiescent and secrete small amounts of ECM components, whereas, in pathological conditions, they ...
    • Norambuena Soto, Ignacio; Núñez Soto, Constanza; Sanhueza Olivares, Fernanda; Cancino Arenas, Nicole; Mondaca Ruff, David; Vivar Sánchez, Raúl; Díaz Araya, Guillermo; Mellado, Rosemarie; Chiong Lay, Mario (IRCA-BSSA, 2017)
      Fibroblasts play several homeostatic roles, including electrical coupling, paracrine signaling and tissue repair after injury. Fibroblasts have low secretory activity. However, in response to injury, they differentiate to ...