Browsing by Author "López Alarcón, Camilo"
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Valenzuela, V.; Santander, P.; Camargo Grandón, Rodrigo; Squella Serrano, Juan; López Alarcón, Camilo; Núñez Vergara, Luis (TAYLOR & FRANCIS, 2004-07)In the present paper, a direct quenching of radical species by a number of synthesized nitrosoaryl 1,4-dihydropyridines and their parent nitroaryl 1,4-dihydropyridines was determined in aqueous media at pH 7.4. These two ...
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Bridi, R.; Troncoso, M. J.; Folch Cano, Christian; Fuentes, J. Rodrigo; Speisky Cosoy, Hernán; López Alarcón, Camilo (Springer New York LLC, 2014)© 2014, Springer Science+Business Media New York. The use of a Folin–Ciocalteu (FC) assay to assess total phenolics in certain foods may be limited by the inability of this assay to discriminate between phenolics and ...
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Ortiz, Rocío; Antilén, Mónica; Speisky Cosoy, Hernán; Aliaga, Margarita E.; López Alarcón, Camilo (2011)The analytical parameters of the microplatebased oxygen radicals absorbance capacity (ORAC) method using pyrogallol red (PGR) as probe (ORAC-PGR) are presented. In addition, the antioxidant capacity of commercial beverages, ...
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Atala, E.; Aspée, Alexis; Speisky Cosoy, Hernán; Lissi Gervaso, Eduardo A.; López Alarcón, Camilo (2013)A novel ORAC (oxygen radical absorbance capacity) assay to assess antioxidant capacity of phenolic compounds in near-gastric conditions (pH 2.0) is presented. AAPH (2,2'-azo-bis(2-amidinopropane)dihydrochloride) was used ...
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López Alarcón, Camilo; Speisky Cosoy, Hernán; Lissi Gervaso, Eduardo (Society of Biology of Chile, 2007)The antioxidant effect of 5-Aminosalicylic acid (5-ASA) on copper-mediated LDL oxidation was followed either by the emitted chemiluminiscence (CL) or by UV-vis spectroscopy. 5-ASA addition extends the lag phase in a ...
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Speisky Cosoy, Hernán; Rocco, Claudia; Carrasco, Catalina; Lissi Gervaso, Eduardo A.; López Alarcón, Camilo (JOHN WILEY, 2006-06)Herbal tea consumption is deeply and widely rooted amongst South-American populations. In view of the involvement of oxygen- and nitrogen-reactive species in the ethiogenesis of several diseases, the antioxidant properties ...
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Ortiz, Rocío; Antilén, Mónica; Speisky Cosoy, Hernán; Aliaga, Margarita E.; López Alarcón, Camilo; Baugh, Steve (AOAC International, 2012)The method was approved by the Expert Review Panel on Strategic Foods Analytical Methods as First Action. See "Standards News," (2012) Inside Laboratory Management, March/April issue. The AOAC Stakeholder Panel on Strategic ...
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Atala, E.; Vásquez, L.; Speisky Cosoy, Hernán; Lissi Gervaso, Eduardo A.; López Alarcón, Camilo (2009)An oxygen radical absorbance capacity (ORAC) method based on pyrogallol red bleaching (ORAC-PGR) was used to evaluate the scavenging activity of berry extracts (blackberry, blueberry, and raspberry). Among berry extracts, ...
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Arenas, Andrea; López Alarcón, Camilo; Kogan Bocian, Marcelo; Lissi Gervaso, Eduardo A.; Davies, Michael J.; Silva, Eduardo (2013)Chemical and structural alterations to lysozyme (LYSO), glucose 6-phosphate dehydrogenase (G6PD), and bovine eye lens proteins (BLP) promoted by peroxyl radicals generated by the thermal decomposition of 2,2′-azobis(2- ...
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Arenas, Andrea; López Alarcón, Camilo; Kogan Bocian, Marcelo; Lissi Gervaso, Eduardo A.; Davies, Michael; Silva, Eduardo (2013)Chemical and structural alterations to lysozyme (LYSO), glucose 6-phosphate dehydrogenase (G6PD), and bovine eye lens proteins (BLP) promoted by peroxyl radicals generated by the thermal decomposition of 2,2′-azobis(2 ...
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Cruces, E.; Rojas Lillo, Y.; Ramírez Kushel, E.; Atala, E.; López Alarcón, Camilo; Lissi Gervaso, Eduardo A.; Gómez, I. (Springer Science+Business, 2016)Preservation, storage, and safe transport of samples are key factors affecting brown algal phlorotannin (phenolics) quantification, their extraction yield, and antioxidant activity. This is especially relevant when field ...
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Speisky Cosoy, Hernán; Gómez, Maritza; Carrasco Pozo, Catalina; Pastene, Edgar; López Alarcón, Camilo; Olea Azar, Claudio (2008)Cu(2+) ions and and GSH molecules interact swiftly to form the complex Cu(I)–glutathione. We investigated the potential capacity of such complex to reduce molecular oxygen. The addition of SOD to a solution containing ...
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Speisky Cosoy, Hernán; Gómez, Maritza; Carrasco Pozo, Catalina; Pastene, Edgar; López Alarcón, Camilo; Olea Azar, Claudio (PERGAMON-ELSEVIER SCIENCE LTD, 2008-07-01)Cu2+ ions and GSH molecules interact to swiftly form the complex Cu(I)–glutathione. We investigated the potential capacity of such complex to reduce molecular oxygen. The addition of SOD to a solution containing Cu(I)– ...
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Aliaga, Margarita E.; Carrasco Pozo, Catalina; López Alarcón, Camilo; Speisky Cosoy, Hernán (Springer, 2010)Cu2? ions and reduced glutathione (GSH) swiftly interact to form the physiologically occurring Cu(I)–[GSH]2 complex. Prompted by the recently reported ability of this complex to generate superoxide radicals from molecular ...
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Cu(II)–disulfide complexes display simultaneous superoxide dismutase- and catalase-like activities Aliaga, Margarita E.; Andrade Acuña, Daniela; López Alarcón, Camilo; Sandoval Acuña, Cristián; Speisky Cosoy, Hernán (Elsevier, 2013)Superoxide is a potentially toxic by-product of cellular metabolism.We have addressed here the in vitro ability of complexes formed between copper(II) ions and various biologically-occurring disulfides (RSSR: oxidized ...
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López Alarcón, Camilo; Squella Serrano, Juan; Núñez Vergara, Luis; Báez Guerrero, Hernán; Camargo Grandón, Rodrigo (JOHN WILEY, 2002)A gas chromatography/mass spectrometry (GC/MS) method for the qualitative and quantitative determination of the calcium-channel antagonists C-4-substituted 1,4-dihydropyridines, and their corresponding N-ethyl derivatives, ...
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Speisky Cosoy, Hernán; Gómez, Maritza; Burgos Bravo, Francesca; López Alarcón, Camilo; Jullian Matthaei, Carolina; Olea Azar, Claudio; Aliaga, Margarita E. (PERGAMON-ELSEVIER SCIENCE LTD, 2009-03-01)The interaction between Cu2+ ions and GSH molecules leads to the swift formation of the physiologically occurring Cu(I)-[GSH](2) complex. Recently, we reported that this complex is able to reduce molecular oxygen into ...
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Carrasco Pozo, Catalina; Álvarez Lueje, Alejandro; Olea Azar, Claudio; López Alarcón, Camilo; Speisky Cosoy, Hernán (SOC EXPERIMENTAL BIOLOGY MEDICINE, 2006-10)Homocysteine (Hcys) has been implicated in various oxidative stress–related disorders. The presence of a thiol on its structure allows Hcys to exert a double-edge redox action. Depending on whether Cu2þions occur ...
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Sandoval Acuña, Cristian; López Alarcón, Camilo; Aliaga, Margarita E.; Speisky Cosoy, Hernán (2012)Mitochondrial dysfunction plays a major role in the development of oxidative stress and cytotoxicity induced by non-steroidal anti-inflammatory drugs (NSAIDs). A major objective of the present study was to investigate ...
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López Alarcón, Camilo; Lissi, E.; Hoffmann, P.; Mella, J.; Pessoa Mahana, Carlos David; Speisky Cosoy, Hernán; Möller, M.; Ferrer-Sueta, G.; Denicola, A. (2011)The reaction of 5-aminosalicylic acid (5-ASA) with nitrous acid has been studied at low pH under conditions that simulate a gastric environment. The course of the reaction was followed by UV-visible and fluorescence ...