Browsing by Author "Contreras Ferrat, Ariel Eduardo"

Now showing items 21-31 of 31

    • Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through ... 
      Del Campo Sfeir, Andrea Estefanía; Parra Ortíz, María Valentina; Vásquez Trincado, César Alonso; Gutiérrez, Tomás; Morales, Pablo E.; López Crisosto, Camila; Bravo Sagua, Roberto; Navarro Márquez, Mario F.; Verdejo, Hugo E.; Contreras Ferrat, Ariel Eduardo; Troncoso Cotal, Rodrigo; Chiong Lay, Mario; Lavandero González, Sergio (American Physiological Society, 2014)
      Insulin is a major regulator of glucose metabolism, stimulating its mitochondrial oxidation in skeletal muscle cells. Mitochondria are dynamic organelles that can undergo structural remodeling in order to cope with these ...
    • Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through ... 
      Del Campo, Andrea; Parra, Valentina; Vásquez Trincado, César Alonso; Gutiérrez, Tomás; Morales, Pablo E.; López Crisosto, Camila; Bravo Sagua, Roberto; Navarro Márquez, Mario F.; Verdejo, Hugo E.; Contreras Ferrat, Ariel Eduardo; Troncoso, Rodrigo; Chiong Lay, Mario; Lavandero González, Sergio (2014)
      Insulin is a major regulator of glucose metabolism, stimulating its mitochondrial oxidation in skeletal muscle cells. Mitochondria are dynamic organelles that can undergo structural remodeling in order to cope with these ...
    • Modulación del calcio intracelular por insulina en el cardiomiocito de rata adulta 
      Pivet Silva, Deisy Carolina (Universidad de ChileCyberDocs, 2010)
      El cardiomiocito adulto es una célula terminalmente diferenciada con escasa capacidad replicativa y responsable de la contracción del miocardio. El ión calcio en conjunto con el AMP cíclico son los segundos mensajeros que ...
    • NOX2-Dependent ROS Production is Essential for the Response to Endurance Exercise in Skeletal Muscle 
      Henríquez Olguín, Carlos; Valladares Ide, Denisse; Díaz Vegas, Alexis; Utreras Mendoza, Yildy; Campos, Cristian; Llanos Vidal, Paola; Contreras Ferrat, Ariel Eduardo; Espinosa Escalona, Alejandra; Altamirano, Francisco; Arias Calderón, Manuel (Federation of American Societies for Experimental Biology, 2015)
    • Nuevas vías de transducción en la captación de glucosa dependiente de insulina en cultivos de cardiomiocitos ... 
      Carrillo Ballesteros, Constanza Carolina (Universidad de Chile, 2010)
      A pesar de que el Ca+2 posee un papel fundamental en regular la función contráctil del cardiomiocito adulto, se desconoce si este ión media las acciones metabólicas de insulina, especialmente aquellas relacionadas con el ...
    • Participación de la vía transduccional IP3-Receptor de IP3-Calcio en la acción de insulina en células ... 
      Vásquez Trincado, César Alonso (Universidad de Chile, 2011)
      El músculo esquelético, uno de los principales tejidos sensibles a insulina, es el principal encargado del mantenimiento de la homeostasis de la glucosa, disponiendo de alrededor de un 80% de la glucosa circulante postprandial, ...
    • Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability 
      Pedrozo Cibils, Zully; Criollo Céspedes, Alfredo; Battiprolu, Pavan K.; Morales, Cyndi R.; Contreras Ferrat, Ariel Eduardo; Fernández, Carolina; Jiang, Nan; Luo, Xiang; Caplan, Michael J.; Somlo, Stefan; Rothermel, Beverly A.; Gillette, Thomas G.; Lavandero González, Sergio; Hill, Joseph A. (Lippicott Williams & Wilkins, 2015)
      Background-L-type calcium channel activity is critical to afterload-induced hypertrophic growth of the heart. However, the mechanisms governing mechanical stress-induced activation of L-type calcium channel activity are ...
    • Potential role of skeletal muscle glucose metabolism on the regulation of insulin secretion 
      Mizgier, María Luisa; Casas Atala, Mariana; Contreras Ferrat, Ariel Eduardo; Llanos Vidal, Paola; Galgani Fuentes, José (2014)
      Pancreatic beta cells sense glucose flux and release as much insulin as required in order to maintain glycaemia within a narrow range. Insulin secretion is regulated by many factors including glucose, incretins, and ...
    • Regulatory volume decrease in cardiomyocytes is modulated by calcium influx and reactive oxygen species 
      Rojas Rivera, Andrés; Díaz Elizondo, Jessica; Parra Ortíz, María Valentina; Salas, Daniela; Contreras Ferrat, Ariel Eduardo; Toro, Barbra; Chiong Lay, Mario; Olea Azar, Claudio; Lavandero González, Sergio (ELSEVIER SCIENCE BV, 2009-11-03)
      We investigated the role of Ca2+ in generating reactive oxygen species (ROS) induced by hyposmotic stress (Hypo) and its relationship to regulatory volume decrease (RVD) in cardiomyocytes. Hypo-induced increases in cytoplasmic ...
    • ROS Production via P2Y(1)-PKC-NOX2 Is Triggered by Extracellular ATP after Electrical Stimulation of Skeletal ... 
      Díaz Vegas, Alexis; Campos, Cristian A.; Contreras Ferrat, Ariel Eduardo; Casas Atala, Mariana; Buvinic Radic, Sonja; Jaimovich Pérez, Enrique; Espinosa Escalona, Alejandra (Public Library Science, 2015)
      During exercise, skeletal muscle produces reactive oxygen species (ROS) via NADPH oxidase (NOX2) while inducing cellular adaptations associated with contractile activity. The signals involved in this mechanism are still a ...
    • ROS production via P2Y1-PKC-NOX2 is triggered by extracellular ATP after electrical stimulation of skeletal ... 
      Díaz Vegas, Alexis; Campos, Cristian A.; Contreras Ferrat, Ariel Eduardo; Casas, Mariana; Buvinic, Sonja; Jaimovich Pérez, Enrique; Espinosa, Alejandra (Public Library of Science, 2015)
      © 2015 Díaz-Vegas et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...