Now showing items 20461-20480 of 92058

    • Cassels Niven, Bruce; Eckardt, G.; Kaussmann, E. U.; Tschesche, R. (Pergamon Press, 1974-02-20)
      The known alkaloids zizyphine-A (1) and -B (2), abyssinine-A (4) and -B (5), and the previously undescribed zizyphine-C (3), -D (6) and -E (7) have been isolated from the stem bark of Zizyphus oenoplia. The structures ...
    • Pino, Karina; Michea, Paula; Sauma Mahaluf, Daniela; Alba, Andrea; Morales, Jorge; Bono Merino, María Rosa; Fierro, Alberto; Rosemblatt Silber, Mario César (SOC BIOLGIA CHILE, 2010-08-12)
      One of the mechanisms for generation of tolerance involves immature dendritic cells (DCs) and a subpopulation of regulatory CD4+ CD25+ T lymphocytes (TREG). The purpose of this work was to analyze how Cyclosporine A (CsA), ...
    • Pino Lagos, Karina; Michea, Paula; Sauma Mahaluf, Daniela; Alba, Andrea; Morales, Jorge; Bono Merino, María Rosa; Fierro, Alberto; Rosemblatt Silber, Mario César (Society of Biology of Chile, 2010)
      One of the mechanisms for generation of tolerance involves immature dendritic cells (DCs) and a subpopulation of regulatory CD4+ CD25+ T lymphocytes (TREG). The purpose of this work was to analyze how Cyclosporine A (CsA), ...
    • Groenendyk, Jody; Paskevicius, Tautvydas; Urra, Hery; Viricel, Clement; Wang, Kui; Barakat, Khaled; Hetz Flores, Claudio; Kurgan, Lukasz; Agellon, Luis B.; Michalak, Marek (Nature Publishing Group, 2018)
      © 2018, The Author(s). Cyclosporine, a widely used immunosuppressant in organ transplantation and in treatment of various autoimmune diseases, activates the unfolded protein response (UPR), an ER stress coping response. ...
    • Sauma Mahaluf, Daniela; Fierro, Alberto; Mora, J.R.; Lennon Duménil, Ana María; Bono Merino, María Rosa; Rosemblatt Silber, Mario César; Morales Peña, José (ELSEVIER, 2003-11)
      The mode of action of cyclosporine (CsA) has been ascribed to its capacity to inhibit IL-2 and IFNgamma production by T cells, two cytokines implicated in allograft rejection. Recently, it has been reported that upon ...
    • Muñoz, R.; Espinoza, M.; Espinoza, Omar; Andrade, A.; Bravo, Eduardo; González, F. (ELSEVIER, 2006-04)
      Leukoencephalopathy is a structural alteration of cerebral white matter mainly involving damage to myelin. Several reports have linked cyclosporine (CsA) with this alteration. The clinical features vary from qualitative ...
    • Phan, Tung Gia; Luchsinger Farías, Vivian; Avendaño Carvajal, Luis; Deng, Xutao; Delwart, Eric (Society for General Microbiology, 2014)
      Some respiratory tract infections remain unexplained despite extensive testing for common pathogens. Nasopharyngeal aspirates (NPAs) from 120 Chilean infants from Santiago with acute lower respiratory tract infections were ...
    • Castander, F. J.; Treister, Ezequiel; Maza Sancho, José; Coppi, P. S.; Maccarone, Thomas J.; Zerpf, S. E.; Guzmán, R.; Ruiz González, María Teresa (2003)
      We present the Cal´an-Yale Deep Extragalactic Research (CYDER) Survey. The broad goals of the survey are the study of stellar populations, the star formation history of the universe and the formation and evolution of ...
    • Mandakovic Seyler, Dinka; Trigo, Carla; Andrade, Derly; Riquelme, Brenda; Gómez Lillo, Gabriela; Soto Liebe, Katia; Díez, Beatriz; Vásquez, Mónica (Frontiers Media S.A., 2016)
      Cell division in bacteria has been studied mostly in Escherichia coli and Bacillus subtilis, model organisms for Gram-negative and Gram-positive bacteria, respectively. However, cell division in filamentous cyanobacteria ...
    • Cortes, Maria de los Angeles; Campa, Raquel de la; Valenzuela, Maria Luisa; Díaz, Carlos; Carriedo, Gabino A.; Soto, Alejandro Presa (MDPI AG, 2019)
      During the last number of years a variety of crystallization-driven self-assembly (CDSA) processes based on semicrystalline block copolymers have been developed to prepare a number of different nanomorphologies in solution ...
    • Quiñones Sepúlveda, Luis; Lucas, D.; Godoy, J.; Cáceres Lillo, Dante; Berthou, F.; Varela Figueroa, Nelson; Lee, K.; Acevedo, C.; Martínez, L.; Aguilera, A. M.; Gil, Lionel (Elsevier, 2001)
      CYP1A1, CYP2E1 and GSTM1 polymorphisms were evaluated in Chilean healthy controls and lung cancer patients. In the Chilean healthy group, frequencies of CYP1A1 variant alleles for MspI (m2 or CYP1A1*2A) and ile/val (val ...
    • Krall Opazo, Paola; Yáñez, Dominique; Rojo, Angélica; Delucchi Bicocchi, María Angela; Córdova, Miguel; Morales, Jorge; Boza, Pía; Rivera, Alonso de la; Espinoza, Natalie; Armijo, Natalia; Castañeda, Luis E.; Farfán Urzúa, Mauricio; Salas, Carolina (Frontiers Media, 2021)
      Background: Tacrolimus (TAC) and mycophenolic acid (MPA) are the main immunosuppressive drugs used in pediatric kidney transplantation. Single nucleotide polymorphisms (SNPs) in metabolizing enzymes and transporters might ...
    • Espinoza Navarro, Omar; Arriaza Onel, Camilo; Cereceda, Carlos; Rodríguez Bustos, Héctor (Asociación Interciencia, 2016)
      Cypermethrin is a synthetic pyrethroid widely used as an agropesticide. The aim of this study was to determine the effect of cypermethrin on reproductive patterns of the planarian Dugesia gonocephala, a bioindicator ...
    • Toro, Patricia; Suazo, Constanza; Acuña, Alejandra; Fuentealba, Mauricio; Artigas, Vania; Arancibia, Rodrigo; Olea Azar, Claudio; Moncada, Mauricio; Wilkinson, Shane; Klahn, A. Hugo (Elsevier, 2018)
      A novel series of cyrhetrenyl (3a-4a) and ferrocenyl (3b-4b) Schiff bases were synthesized through a condensation reaction, between the known 4-ferrocenylaniline (2b) or the unreported 4-cyhretrenylaniline (2a) with 4-or ...
    • Valle, A.; López-Castilla, A.; Pedrera, L.; Martínez, D.; Tejuca, M.; Campos, J.; Fando, R.; Lissi, E.; Álvarez, C.; Lanio, M. E.; Pazos, F.; Schreier, S. (2011)
      Experimental evidence shows that the mechanism of pore formation by actinoporins is a multistep process, involving binding of the water-soluble monomer to the membrane and subsequent oligomerization on the membrane surface, ...
    • Wolff Fernández, Carlos; Durruty A., Pilar; Espinoza R., Jaime; Ripamonti Z., Soledad; Díaz C., Jaime (2009)
      Background: Patients with type 2 diabetes have a high incidence of coronary artery disease, which is even higher among those with renal failure. Serum levels of cystatin C are used to assess renal function and is a potential ...
    • Feijóo, Carmen Gloria; Sarrazín, Andrés F.; Allende Connelly, Miguel; Glavic Maurer, Álvaro (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2009-04-15)
      The CSRNP (cystein-serine-rich nuclear protein) family has been conserved from Drosophila to human. Although knockout mice for each of the mammalian proteins have been generated, their function during vertebrate development ...
    • Villagra, Nicolás A.; Valenzuela, L. Matías; Mora, Aracely Y.; Millanao, Ana R.; Saavedra, Claudia P.; Mora, Guido C.; Hidalgo, Alejandro A. (Elsevier B.V., 2019)
      Currently, Salmonella enterica serovar Typhimurium (S. Typhimurium), is a major global public health problem, which has caused food-borne illnesses in many countries. Today, with the extensive use of antimicrobials, ...
    • Saona, Luis A.; Campo Giraldo, Jessica L.; Anziani Ostuni, Giovanna; Órdenes Aenishanslins, Nicolás; Venegas, Felipe A.; Giordana, María F.; Díaz, Carlos; Isaacs, Mauricio; Bravo Rodríguez, Denisse Margarita; Pérez Donoso, José M. (MDPI, 2022)
      A one-pot green method for aqueous synthesis of fluorescent copper sulphide nanoparticles (NPs) was developed. The reaction was carried out in borax-citrate buffer at physiological pH, 37 degrees C, aerobic conditions and ...
    • Aretxabala, Xabier de; Roa, Iván; León, Jorge; Maluenda, Fernando (Sociedad Medica de Santiago, 2008)
      Cystic tumors of the pancreas are diagnosed with increasing frequency. The main problems associated with their dia gnosis a re to determine if they are benign of' malingnant and to decide their surgical excision or clinical ...