Now showing items 61689-61708 of 77349

    • Griliches, Zvi (Universidad de Chile. Facultad de Economía y Negocios, 1998-12)
      Recent work on the relationship of productivity growth to expenditures on R&D is discussed with special reference to ""unfinished business"": unsolved conceptual and econometric problems. The standard ""R&D as a capital"" ...
    • Vatter, Jaime E. (Universidad de Chile. Facultad de Economía y Negocios, 1995-06)
      This paper is based on the notion that R&D investment and innovation are the result of decisions taken by optimizing agents. Therefore, the premise is that the economic and institutional environments playa role in their ...
    • Crespi, Gustavo; Katz Sliapnic, Jorge (Universidad de Chile. Departamento de Economía, 1999-12)
      This research submits evidence on the nature of the accumulation of knowledge in Chilean manufacturing industry. Microeconomic data shows that factors which are both firm and the industry specific are relevant to the ...
    • Bebczuk, Ricardo N. (Universidad de Chile. Facultad de Economía y Negocios, 2002-06)
      The goal of this paper is to conduct an empirical investigation on the macroeconomic determinants of research and development (R&D) expenditures and to assess the role of government in the light of recent developments ...
    • Asencio,; Cassels Niven, Bruce; Speisky Cosoy, Hernán; Valenzuela, (1993)
    • Asencio, Marcelo; Cassels Niven, Bruce; Speisky Cosoy, Hernán; Valenzuela Bonomo, Carlos (Elsevier, 1992-10-16)
      The Stem bark of P. boldus, in addition to the previously reported benzylisoquinoline alkaloids. sensu lato, accumulates small amounts of their common precursor (R)- aud (to a lesser extent) (S )-coclaurine.The ...
    • Quintanilla González, María Elena; Rivera Meza, Mario; Berríos Cárcamo, Pablo; Cassels Niven, Bruce; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Wiley-Blackwell, 2016)
      Ethanol is oxidized in the brain to acetaldehyde, which can condense with dopamine to generate (R/S)-salsolinol [(RS)-SAL]. Racemic salsolinol [(RS)-SAL] is self-infused by rats into the posterior ventral tegmental area ...
    • R.O.L.T.A 
      Cortés Márquez, rancisco Javier (Universidad de Chile, 2016)
      El objetivo de la presente investigación es proponer una matriz de representación que permite formular construcciones teóricas en torno al fenómeno de los diferentes grados de posibles procesos de interpretación y persuasión ...
    • Villarroel Campos, David Leonardo; Bronfman, Francisca; González Billault, Christian (John Wiley and Sons Inc., 2016)
      © 2016 Wiley Periodicals, Inc. Neurons are highly polarized cells that contain specialized subcellular domains involved in information transmission in the nervous system. Specifically, the somatodendritic compartment ...
    • Villarroel Campos, David Leonardo; Gastaldi, Laura; Conde, Cecilia; Cáceres, Alfredo; González Billault, Christian (International Society for Neurochemistry, 2014)
      Neuronal cells are characterized by the presence of two confined domains, which are different in their cellular properties, biochemical functions and molecular identity. The generation of asymmetric domains in neurons ...
    • Villarroel Campos, David Leonardo; Henríquez, Daniel R.; Bodaleo, Felipe J.; Oguchi, Mai E.; Bronfman, Francisca; Fukuda, Mitsunori; González Billault, Christian (Society for Neuroscience, 2016)
      © 2016 the authors. Rab35 is a key protein for cargo loading in the recycling endosome. In neuronal immortalized cells, Rab35 promotes neurite differentiation. Here we describe that Rab35 favors axon elongation in rat ...
    • Díaz, Jorge; Mendoza, Pablo; Ortiz, Rina; Díaz, Natalia; Leyton Campos, Lisette; Stupack, Dwayne; Quest, Andrew F. G.; Torres, Vicente A. (Company of Biologists Ltd, 2014)
      Rab5 is a small GTPase that regulates early endosome trafficking and other cellular processes, including cell adhesion and migration. Specifically, Rab5 promotes Rac1 activation and cancer cell migration, but little is ...
    • Halabi, María Teresa; Bahamondes, Francisca; Cattaneo, Gino; Adaro, Luis; Flores, Estefanía (2012)
      Experimental veterinary surgery on small animals -particularly dogs- has restrictions, mainly regarding affect; therefore it is necessary to have a model of the animal to perform such procedures. This model must have ...
    • Casanueva Ruiz, Gabriela (Universidad de Chile, 2012)
      El siguiente trabajo de investigación está centrado en el análisis comparado entre Rabia, la novela de Sergio Bizzio, y Rabia, la película dirigida por Sebastián Cordero. La comparación tiene como sustento las voluntades ...
    • Tobar, Nicolás; Cáceres, Mónica; Santibáñez, Juan Francisco; Smith, Patricio C.; Martínez, Jorge (Elsevier Inc., 2008-08-18)
      modulate the migratory properties in MCF-7 and T47D human mammary cell lines. We also described that the NFjB pathway exerts a downstream control on the expression of the ROS-dependent cellular migratory potential. These ...
    • Santibáñez, Juan Francisco; Kocic, Jelena; Fabra, Angels; Cano, Amparo; Quintanilla, Miguel (ELSEVIER, 2010)
      Transforming growth factor-b1 (TGF-b1) activates Rac1 GTPase in mouse transformed keratinocytes. Expression of a constitutively active Q61LRac1 mutant induced an epithelial to mesenchymal transition (EMT) linked to ...
    • Correa Ávalos, Danae (Universidad de Chile, 2019)
    • Mirizio Pertile, Gerardo Gabriel; Muñoz, Rodrigo; Muñoz, Leandro; Ahumada, Facundo; Coso, Juan del (MDPI, 2021)
      Cross-country mountain biking is an Olympic sport discipline with high popularity among elite and amateur cyclists. However, there is a scarcity of data regarding the key determinants of performance, particularly in young ...
    • Berríos Cárcamo, Pablo; Quintanilla González, María Elena; Herrera-Marschitz Muller, Mario; Vasiliou, Vasilis; Zapata Torres, Gerald; Rivera Meza, Mario (Frontiers Media S.A., 2017)
      © 2017 Berríos-Cárcamo, Quintanilla, Herrera-Marschitz, Vasiliou, Zapata-Torres and Rivera-Meza. Background: Several studies have shown that the ethanol-derived metabolite salsolinol (SAL) can activate the mesolimbic system, ...