Browsing by Author "González Billault, Christian"

Now showing items 41-46 of 46

    • Regulation of Neuronal Cav3.1 Channels by Cyclin-Dependent Kinase 5 (Cdk5) 
      Calderón Rivera, Aída; Sandoval, Alejandro; González Ramírez, Ricardo; González Billault, Christian; Félix, Ricardo (Public Library of Science, 2015)
      Low voltage-activated (LVA) T-type Ca2+ channels activate in response to subthreshold membrane depolarizations and therefore represent an important source of Ca2+ influx near the resting membrane potential. In neurons, ...
    • Searching for Novel Cdk5 Substrates in Brain by Comparative Phosphoproteomics of Wild Type and Cdk5 -/- Mice 
      Contreras Vallejos, Erick; Utreras Puratich, Elías; Bórquez Muñoz, Daniel; Prochazkova, Michaela; Terse, Anita; Jaffe, Howard; Toledo, Andrea; Arruti, Cristina; Pant, Harish C.; Kulkarni, Ashok B.; González Billault, Christian (2014)
      Protein phosphorylation is the most common post-translational modification that regulates several pivotal functions in cells. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase which is mostly ...
    • Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice 
      Contreras Vallejos, Erick; Utreras Puratich, Elías; Bórquez, Daniel A.; Prochazkova, Michaela; Terse, Anita; Jaffe, Howard; Toledo, Andrea; Arruti, Cristina; Pant, Harish C.; Kulkarni, Ashok B.; González Billault, Christian (Public Library of Science, 2014)
      Protein phosphorylation is the most common post-translational modification that regulates several pivotal functions in cells. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase which is mostly ...
    • The Light Chain 1 Subunit of the Microtubule-Associated Protein 1B (MAP1B) Is Responsible for Tiam1 Binding ... 
      Henríquez, Daniel R.; Bodaleo, Felipe J.; Montenegro Venegas, Carolina; González Billault, Christian (2012)
      Microtubule-associated protein 1B (MAP1B) is a neuronal protein involved in the stabilization of microtubules both in the axon and somatodendritic compartments. Acute, genetic inactivation of MAP1B leads to delayed axonal ...
    • The role of small GTPases in neuronal morphogenesis and polarity 
      González Billault, Christian; Muñoz Llancao, Pablo; Henríquez, Daniel R.; Wojnacki, José; Conde, Cecilia; Cáceres, Alfredo (2012)
      The highly dynamic remodeling and cross talk of the microtubule and actin cytoskeleton support neuronal morphogenesis. Small RhoGTPases family members have emerged as crucial regulators of cytoskeletal dynamics. In this ...
    • TNF-α increases production of reactive oxygen species through Cdk5 activation in nociceptive neurons 
      Sandoval Guzmán, Rodrigo; Lazcano Sánchez, Pablo; Ferrari Soto, Franco; Pinto Pardo, Nicolás; González Billault, Christian; Utreras Puratich, Elías (Frontiers Media, 2018)
      The participation of reactive oxygen species (ROS) generated by NOX1 and NOX2/NADPH oxidase has been documented during inflammatory pain. However, the molecular mechanism involved in their activation is not fully understood. ...