Browsing by Title

Now showing items 51618-51637 of 92398

    • IP3 dependent Ca2+ signals in muscle cells are involved in regulation of gene expression 
      Jaimovich Pérez, Enrique; Carrasco, María Angélica (Society of Biology of Chile, 2002)
      Potassium depolarization of cultured muscle cells was employed to study cellular responses linked to calcium signaling. Events occurring after depolarization include i) A transient increase of the IP3 mass (2-10s); ii) A ...
    • IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice 
      Valladares, Denisse; Utreras Mendoza, Yildy; Campos, Cristian; Morales, Camilo; Díaz Vegas, Alexis; Contreras Ferrat, Ariel Eduardo; Westermeier, Francisco; Jaimovich Pérez, Enrique; Marchi, Saverio; Pinton, Paolo; Lavandero González, Sergio (Elsevier B.V., 2018)
      © 2018 Duchenne muscular dystrophy (DMD) is characterized by a severe and progressive destruction of muscle fibers associated with altered Ca2+ homeostasis. We have previously shown that the IP3 receptor (IP3R) plays a ...
    • IP3 receptors, IP3 transients, and nucleus-associated Ca2+ signals in cultured skeletal muscle 
      Jaimovich Pérez, Enrique; Reyes, Roberto; Liberona Leppe, José; Powell, Jeanne A. (Amer Physiological Soc, 2000)
      Inositol 1,4,5-trisphosphate (IP3) receptors (IP3R) and ryanodine receptors (RyR) were localized in cultured rodent muscle fractions by binding of radiolabeled ligands (IP3 and ryanodine), and IP3R were visualized in situ ...
    • IP3-dependent, post-tetanic calcium transients induced by electrostimulation of adult skeletal muscle fibers 
      Casas, Mariana; Figueroa, Reinaldo; Jorquera, Gonzalo; Escobar, Matías; Molgó, Jordi; Jaimovich Pérez, Enrique (2010)
      Tetanic electrical stimulation induces two separate calcium signals in rat skeletal myotubes, a fast one, dependent on Cav 1.1 or dihydropyridine receptors (DHPRs) and ryanodine receptors and related to contraction, and a ...
    • IPC : medicamentos, economía y salud pública 
      Cienfuegos Silva, Jorge Ignacio Esteban (Universidad de Chile, 2012)
      El medicamento es un elemento de alta complejidad, no sólo desde el punto de vista de la tecnología asociada y la repercusión que tienen estos en el tratamiento de las enfermedades, sino también es un bien transable en el ...
    • IPIDV: internado para la preparación a la integración de los discapacitados visuales en Talca 
      Gómez Carrasco, Juan Pablo (Universidad de Chile, 2008)
      El desafío de generar un proyecto arquitectónico profesionalizante o bien proyecto de titulación, a mi modo de ver en la Universidad de Chile se ha comprendido como una instancia en la que los alumnos convergen sus ...
    • IPNA clinical practice recommendations for the diagnosis and management of children with steroid-resistant ... 
      Trautmann, Agnes; Vivarelli, Marina; Samuel, Susan; Gipson, Debbie; Sinha, Aditi; Schaefer, Franz; Hui, Ng Kar; Boyer, Olivia; Saleem, Moin A.; Feltran, Luciana; Müller-Deile, Janina; Becker, Jan Ulrich; Cano Schuffeneger, Francisco; Xu, Hong; Lim, Yam Ngo; Smoyer, William; Anochie, Ifeoma; Nakanishi, Koichi; Hodson, Elisabeth; Haffner, Dieter (Springer, 2020)
      Idiopathic nephrotic syndrome newly affects 1-3 per 100,000 children per year. Approximately 85% of cases show complete remission of proteinuria following glucocorticoid treatment. Patients who do not achieve complete ...
    • The Iquique earthquake sequence of April 2014: Bayesian modeling accounting for prediction uncertainty 
      Duputel, Z.; Jiang, J.; Jolivet, R.; Simons, M.; Rivera, L.; Ampuero, J. P.; Riel, B.; Owen, S. E.; Moore, A. W.; Samsonov, S. V.; Ortega Culaciati, Francisco; Minson, S. E. (AGU Publications, 2015)
      The subduction zone in northern Chile is a well-identified seismic gap that last ruptured in 1877. On 1 April 2014, this region was struck by a large earthquake following a two week long series of foreshocks. This study ...
    • Iquique Glorioso Crónicas de la Tierra de Campeones 
      Palma Arriegada, Francisca (Universidad de Chile, 2013)
      “El que quiere saber sobre Iquique no debe ver los libros de historia, debe encontrarse y hacerse amigo de un iquiqueño”. Así comienza una conversación el investigador y poeta iquiqueño, Guillermo Ross Murray Lay Kim, ...
    • Iquique: orígenes de su arquitectura en madera del siglo XIX 
      Pizzi Kirschbaum, Marcela (Universidad de Chile. Facultad de Arquitectura y Urbanismo, 1990)
    • Ir & venir : objetos y recuerdos de viaje 
      Oroquieta Fairlie, Catalina (Universidad de Chile, 2019)
    • IR AND 13C-NMR SPECTRAL PROPERTIES OF THE LAYERED INCLUSION COMPOUND BIS(THIOUREA)HEXAMETHYLENETETRAMINE 
      Jara Vergara, Paul; González Moraga, Guillermo; Manríquez Castro, Víctor; Wittke, Oscar; Yutronic Sáez, Nicolás (Sociedad Química Chilena, 2003-10-02)
      The structure of the 1: 2 adduct of hexamethylenetetramine and thiaurea was reanalyzed reinterpreting X-ray diffractian data and providing additianal IR and NMRspectrascapic features. The praduct is thus described as ...
    • IR and NMR spectroscopic correlation of enterobactin by DFT 
      Moreno, M.; Zacarias, A.; Porzel, A.; Velásquez, L.; González Moraga, Guillermo; Alegría Arcos, M.; González Nilo, F.; Gross, E. K. U. (Elsevier, 2018-06)
      Emerging and re-emerging epidemic diseases pose an ongoing threat to global health. Currently, Enterobactin and Enterobactin derivatives have gained interest, owing to their potential application in the pharmaceutical ...
    • Ira, miedo y Reforma Agraria: las emociones en el discurso de la SNA entre las leyes de Reforma agraria : ... 
      Arriaza Peña, Rafael Alejandro (Universidad de Chile, 2019)
      Es conocida la importancia que posee el proceso de Reforma Agraria dentro de la historia reciente de Chile, porque buscó modificar la estructura de la sociedad agraria que había predominado, en no poca medida, desde la ...
    • IRAS 16547−4247: A New Candidate of a Protocluster Unveiled with ALMA 
      Higuchi, Aya; Saigo, Kazuya; Chibueze, James O.; Sanhueza, Patricio; Takakuwa, Shigehisa; Garay Brignardello, Guido (American Astronomical Society, 2015)
      We present the results of continuum and 12CO(3–2) and CH3OH(7–6) line observations of IRAS 16547−4247 made with the Atacama Large Millimeter/submillimeter Array (ALMA) at an angular resolution of ∼0. 5. The 12CO(3–2) ...
    • IRAS 16547−4247: a new candidate of a protocluster unveiled with ALMA 
      Higuchi, Aya; Saigo, Kazuya; Chibueze, James; Sanhueza, Patricio; Takakuwa, Shigehisa; Garay Brignardello, Guido (The American Astronomical Society, 2015-01-10)
      We present the results of continuum and 12CO(3–2) and CH3OH(7–6) line observations of IRAS 16547−4247 made with the Atacama Large Millimeter/submillimeter Array (ALMA) at an angular resolution of ∼0. 5. The 12CO(3–2) ...
    • Irán - Tercermundismo y contra-hegemonía. Elementos para entender el acercamiento iraní hacia Venezuela 
      Alvarez Cabello, Pablo Andrés (Universidad de Chile, 2011)
      Para comenzar con nuestra investigación debemos definir ciertos conceptos clave para comprender, desde nuestra óptica, el comportamiento internacional de Irán. En el primer capítulo, por lo tanto, nos encargamos de tratar ...
    • Irán y el poder atómico: Caracterización de un discurso político nuclear 
      Ortega Pérez, Diego Antonio (Universidad de Chile, 2021)
      La siguiente investigación tiene como propósito general explorar el poder atómico de una nación a través de la caracterización de un discurso político en su vertiente nuclear. Para ello se identifica a Irán como un ...
    • IRE1 alpha governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A 
      Urra, Hery; Henríquez, Daniel R.; Cánovas, José; Villarroel Campos, David; Carreras Sureda, Amado; Pulgar, Eduardo; Molina, Emiliano; Hazari, Younis M.; Limia, Celia M.; Álvarez Rojas, Sebastián; Figueroa, Ricardo; Vidal, René L.; Rodríguez, Diego A.; Rivera, Claudia A.; Court, Felipe A.; Couve Correa, Andrés; Qi, Ling; Chevet, Eric; Akai, Ryoko; Iwawaki, Takao; Concha, Miguel L.; Glavic Maurer, Álvaro; González Billault, Christian; Hetz Flores, Claudio (Nature, 2018)
      Maintenance of endoplasmic reticulum (ER) proteostasis is controlled by a signalling network known as the unfolded protein response (UPR). Here, we identified filamin A as a major binding partner of the ER stress transducer ...
    • IRE1 signaling exacerbates Alzheimer's disease pathogenesis 
      Durán Aniotz, Claudia; Cornejo, Victor Hugo; Espinoza, Sandra; Ardiles, Alvaro O.; Medinas Bilches, Danilo; Salazar, Claudia; Foley, Andrew; Gajardo, Ivana; Thielen, Peter; Iwawaki, Takao; Scheper, Wiep; Soto, Claudio; Palacios, Adrian G.; Hoozemans, Jeroen J. M.; Hetz Flores, Claudio (Springer, 2017)
      Altered proteostasis is a salient feature of Alzheimer's disease (AD), highlighting the occurrence of endoplasmic reticulum (ER) stress and abnormal protein aggregation. ER stress triggers the activation of the unfolded ...