Browsing by Title
Now showing items 78823-78842 of 92826
-
(American Society for Biochemistry and Molecular Biology Inc., 2017)© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.Allosteric modulators of pentameric ligand-gated ion channels are thought to act on elements of the pathways that couple agonist binding to channel ...
-
(Karger, 2014)Objective: To determine whether oral glucose tolerance tests (OGTT) play a role as predictors of preeclampsia (PET) in pregnant women. Methods: A retrospective case-control study was conducted in 2,002 singleton pregnancies ...
-
(Universidad de Chile, 2022)It has been described that both antiretroviral therapy and infection by the human immunodeficiency virus type-1 (HIV-1) causes mitochondrial dysfunction in CD4+ T cells. In large-scale proteomics studies, the HIV-1 Rev ...
-
(1986)The inner protein shell of human rotavirus consists of a single polypeptide called VP6 which was removed from the single-shelled virus by treatment with CaCl2, leaving the viral core. The core thus obtained was unable to ...
-
(Springer New York LLC, 2005)Recent studies show that inflammation has an active role in the onset of neurodegenerative diseases. It is known that in response to extracellular insults microglia and/or astrocytes produce inflammatory agents. These ...
-
(SOC CHILENA QUIMICA, 2008-03)Pyrolysis of the mixtures: [NP(O2C12H8)] // AuCl(PPh2) system (I) [NP(O2C2H8)(0.8)[NP(OC6H4CH2CN.{Ru})(2)](0.15) NP(OC6H5)1OC(6)H(4)CH(2)CN.[Ru](0.05)](n) // (BuSiMe2Cl)-Bu-1 system (II) and N3P3[NH(CH2)(3)Si(OEt)(3)](6) ...
-
(WILEY-BLACKWELL, 2012-01)Synaptic function is crucially dependent on the spatial organization of the presynaptic and postsynaptic apparatuses and the juxtaposition of both membrane compartments. This precise arrangement is achieved by a protein ...
-
(Society of Biology of Chile, 2005)The specific signaling connections between the mitogen-activated protein kinases (MAPK) such as c-Jun N-terminal kinase (JNK-1) and phosphatases PP4 and M3/6, affecting the family of early nuclear factors, is complex and ...
-
Role of the Planar Cell Polarity Pathway in the Morphogenesis of the Laterality Organ in Zebrafish (Universidad de Chile, 2009)A pesar de su aparente simetría bilateral, el plan corporal de los vertebrados presenta consitentes asimetrías en localización, estructura y función de diversos órganos internos como el corazón, los intestinos y el cerebro. ...
-
(Frontiers Media, 2022)Advances in our understanding of cancer biology have contributed to generating different treatments to improve the survival of cancer patients. However, although initially most of the therapies are effective, relapse and ...
-
(1971)Acute infusions of angiotensin II or dog renin into hypophysectomized nephrectomized dogs has no effect on the conversion of corticosterone to aldosterone. This conversion was measured in an isolated mitochondrial fraction ...
-
Role of the RhoA/ROCK pathway in high-altitude associated neonatal pulmonary hypertension in lambs (Amer Physiological Soc, 2016)Exposure to high-altitude chronic hypoxia during pregnancy may cause pulmonary hypertension in neonates, as a result of vasoconstriction and vascular remodeling. We hypothesized that susceptibility to pulmonary hypertension, ...
-
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 1998-12-04)We investigated the role of individual charged residues of the S4 region of a MaxiK channel (hSlo) in channel gating, We measured macroscopic currents induced by wild type (WT) and point mutants of hSlo in inside-out ...
-
(Wiley, 2017)BackgroundIntrathecal/intracisternal BDNF in rodents produces long-lasting hyperalgesia/allodynia, which implies BDNF plays a role in the establishment and maintenance of central sensitization. Both self-regeneration of ...
-
(BioScientifica Ltd., 2010)Fifty to seventy percent of patients with polycystic ovary syndrome (PCOS) present hyperinsulinemia. On the other hand, reports indicate that forkhead box class O 1 (FOXO1) and peroxisome proliferator-activated receptor-g ...
-
(Springer, 2015)Tree plantations may play a role in the conservation of global forest biodiversity. At the landscape scale, plantations with a complex understory may provide surrogate habitats for forest-dwelling organisms. This was tested ...
-
(2013)The endoplasmic reticulum (ER) is a key subcellular compartment involved in the folding and maturation of around one-third of the total proteome. Accumulation of misfolded proteins in the ER lumen engages a signal transduction ...
-
(2011)Using an integrative approach at the whole animal, isolated vessels, and molecular levels, we tested the hypothesis that the llama, a species that undergoes pregnancy under the influence of the chronic hypoxia of high ...
-
(SOC BIOLGIA CHILE, 2006)Thyroid hormone (TH; 3,3,,5-triiodothyronine, T-3) is required for the normal function of most tissues, with major effects on O-2 consumption and metabolic rate. These are due to transcriptional activation of respiratory ...