Browsing by Author "95bc464d-a688-4a28-bcf0-839034cbfb79"
Now showing items 21-39 of 39
-
Marchand, Fabien; Alloui, Abdelkrim; Pelissier Serrano, Teresa; Hernández, Alejandro; Authier, Nicolas; Alvarez, Pedro; Eschalier, Alain; Ardid, Denis (Elsevier, 2003)Venlafaxine, a new antidepressant with fewer side effects, could be of interest to reduce neuropathic pain following antineoplasic drug treatment. In the present study, we demonstrated that venlafaxine inhibits hyperalgesia ...
-
Infante Fabres, Claudio; Díaz, Marcelo; Hernández, Alejandro; Constandil, Luis; Pelissier Serrano, Teresa (2007)Chronic pain is associated with N-methyl-D-aspartate (NMDA) receptor activation and downstream production of nitric oxide, which has a pivotal role in multisynaptic local circuit nociceptive processing in the spinal cord. ...
-
Barra, Rafael; Morgan, Carlos; Sáez Briones, Patricio; Reyes Parada, Miguel; Burgos, Héctor; Morales, Bernardo; Hernández, Alejandro (Oxford University Press, 2019)© The Author(s) 2018.Studies in rats have shown that a decrease in either protein content or total dietary calories results in molecular, structural, and functional changes in the cerebral cortex and hippocampus, among ...
-
Flores, Osvaldo; Pérez, Hernán; López Valladares, Luis; Morgan, Carlos; Gatica, Arnaldo; Burgos, Héctor; Olivares, Ricardo; Hernández, Alejandro (2011)Moderate reduction in the protein content of the mother's diet (hidden malnutrition) does not alter body and brain weights of rat pups at birth, but leads to dysfunction of neocortical noradrenaline systems together with ...
-
Constandil, Luis; Pelissier Serrano, Teresa; Soto Moyano, Rubén; Mondaca, Mauricio; Sáez, Hernán; Laurido, Claudio; Muñoz, Carlos; López, Nandy; Hernández, Alejandro (Elsevier Ireland Ltd, 2003)Cytokines produced by spinal cord glia after peripheral inflammation, infection or trauma have a relevant role in the maintenance of pain states. The effect of intrathecally administered interleukin-1β (IL-1β) on spinal ...
-
Hernández, Alejandro; Laurido, Claudio; Mondaca, Mauricio; Pelissier Serrano, Teresa; Burgos, Hector; Soto Moyano, Rubén (2001)Desipramine-induced inhibition of spinal cord nociceptive transmission was studied in rats with or without lesion of the bulbospinal noradrenergic system by recording the C-fiber evoked nociceptive reflex from a hind limb. ...
-
Pérez, Hernán; Hernández, Alejandro; Almli, C. Robert (1987)Field-evoked potentials from the main olfactory bulb in response to stimulation of the olfactory nerve and lateral olfactory tract were measured without and with conditioning stimulation of the locus coeruleus noradrenergic ...
-
Belmar, Jorge; Carreño, Paz; Hernández, Alejandro; Soto Moyano, Rubén (Elsevier Inc., 1996)Experimental studies have shown that malnutrition early in life results in enhanced release of noradrenaline (NA) in the brain. The disturbed mechanism underlying this neurochemical disorder is poorly understood. To test ...
-
Pérez, Hernán; Ruiz, Samuel; Hernández, Alejandro; Soto Moyano, Rubén (1985)Susceptibility to strychnine of somatosensory responses evoked in the prefrontal cortex was studied in normal and protein-malnourished rats in three groups. (a) The normal group was from mothers fed a 21% casein diet. (b) ...
-
Laurido, Claudio; Hernández, Alejandro; Constandil, Luis; Pelissier Serrano, Teresa (ELSEVIER, 2003-11-27)While increasing evidence points to a role for the nitric oxide (NO)/cyclic guanosine 3,5-monophosphate (GMPc) cascade in hyperalgesia and allodynia, participation of the NO/GMPc pathway in synaptic processing in the spinal ...
-
Bravo, David; Tello Ibarra, Paula; Retamal, Jeffri; Pelissier Serrano, Teresa; Laurido, Claudio; Hernández, Alejandro; Constandil, Luis (Elsevier B.V., 2014)© 2014 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.Pannexin 1 (panx1) is a large-pore membrane channel expressed in many tissues of mammals, including neurons and glial ...
-
Ruiz, Samuel; Pérez, Hernán; Hernández, Alejandro; Ramirez, Maritza; Fernandez, Monica; Soto Moyano, Rubén (Informa Healthcare, 1986)The effect of early postnatal malnutrition on the responsiveness of the rat prefrontal cortex was studied by determining excitability thresholds and fatigability to direct cortical stimulation. Malnutrition imposed during ...
-
Soto Moyano, Rubén; Alarcon, Sergio; Hernández, Alejandro; Pérez, Hernán; Ruiz, Samuel; Carreño, Paz; Kusch, Claudia; Belmar, Jorge (1998)Prenatal malnutrition results in increased concentration and release of central noradrenaline, a neurotransmitter that is an important regulator of normal regressive events such as axonal pruning and synaptic elimination. ...
-
Alvarez, Pedro; Hernández, Alejandro; Constandil, Luis; Infante, Claudio; Pelissier Serrano, Teresa (Blackwell Publishing Ltd, 2014)© 2014 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.Chronic arthritis (CA) is a common clinical entity associated with persistent pain and limited response to opioid analgesic therapy. However, ...
-
Lux, Sebastian; Lobos, Nicolas; Lespay Rebolledo, Carolyne; Salas Huenuleo, Edison; Kogan Bocian, Marcelo; Flores, Christian; Pinto, Mauricio; Hernández, Alejandro; Pelissier Serrano, Teresa; Constandil, Luis (Blackwell Publishing Ltd, 2019)© 2018 Royal Pharmaceutical SocietyObjectives: To study the antinociceptive effect of single and repeated doses of resveratrol in a bone cancer pain model, and whether this effect is prevented by the Silent Information ...
-
Mondaca, Mauricio; Hernández, Alejandro; Pérez, Hernán; López Valladares, Luis; Sierralta, Walter; Fernández, Victor; Soto Moyano, Rubén (Elsevier B.V., 2004)Pretreatment with the α2-adrenoceptor agonist clonidine (31.25, 62.5, or 125 μg/kg, i.p.) dose-dependently reduced long-term potentiation (LTP) elicited in vivo in the occipital cortex of anesthetized rats, whereas ...
-
Flores, Osvaldo; Núñez, Héctor; Pérez, Hernán; Morgan, Carlos; Soto Moyano, Rubén; Valladares Boasi, Luis; Burgos, Héctor; Olivares, Ricardo; Hernández, Alejandro (2010)β-Adrenergic receptor stimulation can significantly facilitate synaptic potentiation in the hippocampus and enhance memory processes, but its effect on neocortical plastic mechanisms is less conclusive. In the present study ...
-
Sáez Briones, Patricio; Soto Moyano, Rubén; Burgos, Héctor; Castillo, Amparo; Valladares Boasi, Luis; Morgan, Carlos; Pérez, Hernán; Barra, Rafael; Constandil, Luis; Laurido, Claudio; Hernández, Alejandro (Academic Press Inc., 2015)© 2014 Elsevier Inc.Moderate reduction in dietary protein composition of pregnant rats from 25% to 8% casein, calorically compensated by carbohydrates, has been described as a "hidden malnutrition" because it does not alter ...
-
Hernández, Alejandro; Paeile, Carlos; Pérez, Hernán; Pelissier Serrano, Teresa; Soto Moyano, Rubén (1990)The response of convergent dorsal horn cells to tonic and phasic noxiuos heating and to noxious pinching was studied and after topical application of a solution (30 nmol) of the κ agonist U-50,488H to the dorsal surface ...