Browsing by Author "Videla Cabrera, Luis"
Now showing items 21-40 of 48
-
Urbina Varela, Rodrigo; Castillo, Nataly; Videla Cabrera, Luis; Campo, Andrea del (MDPI, 2020)Mitochondria are the first-line defense of the cell in the presence of stressing processes that can induce mitochondrial dysfunction. Under these conditions, the activation of two axes is accomplished, namely, (i) the ...
-
Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (MDPI, 2020)Nonalcoholic fatty liver disease (NAFLD) is present in approximately 25% of the population worldwide. It is characterized by the accumulation of triacylglycerol in the liver, which can progress to steatohepatitis with ...
-
Araya, Julia; Rodrigo Salinas, Ramón; Videla Cabrera, Luis; Thielemann, Lilian; Orellana, Myriam; Pettinelli, Paulina; Poniachik Teller, Jaime (2004)Hepatic steatosis is a major feature associated with NAFLD (non-alcoholic fatty liver disease). The aims of the present study were to assess the levels of PUFA (polyunsaturated fatty acids) in liver total lipids, ...
-
Carrión, Yasna; Fernández Arancibia, Virginia; Videla Cabrera, Luis (1993)The effect of thyroid hormone administration on liver glutathione (GSH) content and γ-glutamyltransferase activity in the isolated perfused liver was studied for a period of 1-7 days in fed rats following a single dose of ...
-
Fernández, Virginia; Reyes, Solange; Bravo, Sergio; Sepúlveda, Rodrigo; Romanque, Pamela; Santander, Gonzalo; Castillo, Iván; Varela, Patricia; Tapia, Gladys; Videla Cabrera, Luis (2007)Thyroid hormone-induced calorigenesis triggers liver oxidative stress with concomitant TNF-α production by Kupffer cells and up-regulation of gene expression. Considering that cyclin-dependent kinase-2 (CDK-2) performs ...
-
Barrera Ramírez, Cynthia; Valenzuela Báez, Rodrigo; Rincón Cervera, Miguel Ángel; Espinosa, Alejandra; López Arana, Sandra; González Mañan, Daniel; Romero Palacios, Nalda; Vargas, Romina; Videla Cabrera, Luis (Elsevier, 2020)The administration of iron induces liver oxidative stress and depletion of long-chain polyunsaturated fatty acids (LCPUFAs), n-6/n-3 LCPUFA ratio enhancement and fat accumulation, which may be prevented by antioxidant-rich ...
-
Junqueira, Virginia; Simizu, Kiyoko; Van Halsema, Leonardo; Koch, Osvaldo R.; Barros, Silvia B.M.; Videla Cabrera, Luis (Informa Healthcare, 1988)1. Lindane (60 mg/kg) administered orally to rats increased liver cytochrome P-450 content and superoxide radical (O- 2) generation 24 h after treatment, while formation of thiobarbituric acid reactants and NADPH/ADP-supported ...
-
Barros, Silvia B.M.; Videla Cabrera, Luis; Simizu, Kiyoko; Van Halsema, Leonardo; Junqueira, Virginia B.C. (Informa Healthcare, 1988)1. Four hours after treatment of rats with lindane (60 mg/kg), hepatic GSH content was decreased (22% and GSSG was increased (20% while biliary concentration and excretion of both GSH and GSSG and bile flow were diminished. ...
-
Videla Cabrera, Luis; Simizu, Kiyoko; Barros, Silvia B.M.; Junqueira, Virginia (1989)The effects of lindane administration (25–60 mg kg−1 for 24 h) on hepatic oxygen consumption were studied in the isolated perfused rat liver, in the absence and presence of the iron‐chelator free‐radical scavenger ...
-
Videla Cabrera, Luis; Barros, Silvia B.M.; Simizu, Kiyoko; Junqueira, Virginia (1988)The i.p. administration of 60 mg kg−1 body weight of lindane, the γ‐isomer of hexachlorocyclohexane, to fed rats led to an enhancement of hepatic lipid peroxidation after 24 h of treatment. This was evidenced by significant ...
-
Videla Cabrera, Luis; Fernández Arancibia, Virginia; de Marinis, A.; Fernández N., Daniela; Valenzuela, A. (1982)Acetaldehyde administration (0.3 g/kg) to rats fasted overnight induces a reduction in liver reduced glutathione (GSH) content and stimulates lipid peroxidation. An additive effect in the decrease in liver GSH is observed ...
-
Videla Cabrera, Luis; Simizu, K.; Barros, S. B.M.; Junqueira, V. B.C. (Informa Healthcare, 1991)1. Lindane (25-60 mg/kg) at 24 h after dosage induced a dose-dependent increase in oxygen consumption by perfused rat livers, an effect not observed at early times (2-6 h) after administration. About 60% of the increase ...
-
Videla Cabrera, Luis; Fernández Arancibia, Virginia; Cornejo, Pamela; Vargas, Romina (2012)The liver is a major organ responsible for most functions of cellular metabolism and a mediator between dietary and endogenous sources of energy for extrahepatic tissues. In this context, adenosine-monophosphate- (AMP-) ...
-
Ortiz, Macarena; Echeverría González, Francisca; Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (2019-03)
-
Valenzuela Báez, Rodrigo; Illesca, Paola; Echeverría, Francisca; Espinosa, Alejandra; Rincón Cervera, Miguel Ángel; Ortíz, Macarena; Hernández Rodas, María Catalina; Valenzuela Bonomo, Carlos; Videla Cabrera, Luis (Royal Society of Chemistry, 2017)© 2017 The Royal Society of Chemistry.Scope: Non-alcoholic fatty liver disease (NAFLD) is a condition characterized by an increment in the liver fat content, with a concomitant reduction in the content of n-3-long chain ...
-
Haim, D.; Valenzuela, A.; Brañes, M. C.; Fuenzalida, M.; Videla Cabrera, Luis (Instituto de la Grasa, 2012-10)Policosanol comprises a mixture of long-chain aliphatic alcohols from sugarcane wax. More than 50 studies indicate that policosanol decreases serum cholesterol, while others failed to reproduce this effect. The objective ...
-
Lissi Gervaso, Eduardo A.; Cáceres, T.; Llesuy, Susana; Solari, L.; Boveris, Alberto; Videla Cabrera, Luis (Informa Healthcare, 1989)The characteristics of the visible luminescence that follows the lipid peroxidative process were investigated either in the autoxidation of rat brain homogenates or in the azo-bis-arnidinopropane initiated lipid peroxidation ...
-
Fernández Arancibia, Virginia; Videla Cabrera, Luis (Maney Publishing, 1996)Administration of single doses of 0.1 mg of L-3,3′,5-triiodothyronine (T3)/kg for 3 consecutive days to fed rats elicited a marked increase both in the opsonized zymosan-induced luminol-amplified integrated chemiluminescence ...
-
Vega Blanco, María Margarita; Castillo, Teresita; Retamales, Iván; Las Heras, Jorge; Devoto, Luigi; Videla Cabrera, Luis (1994)The steroidogenic capacity and oxidative stress-related parameters of the human corpus luteum (CL) at different stages of the luteal phase were studied under basal and human chorionic gonadotropin (hCG)-stimulated conditions. ...
-
Thielemann, L. E.; Oberhauser, E. W.; Rosenblut, G.; Videla Cabrera, Luis; Valenzuela, A. (1990)Papillary necrosis was observed in the kidneys of rats, 72 h after receiving a single injection of bromoethylamine (BEA). This effect was associated with renal glutathione (GSH) depletion 1 h after the administration of ...